6h2s
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6h2s is ON HOLD until Paper Publication Authors: Crennell, S.J., Danson, M.J., Royer, S. Description: Sulfolobus solfataricus 2-keto-3-deoxyglucona...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/D181Q/A198L variant, pyruvate complex== | |
| + | <StructureSection load='6h2s' size='340' side='right'caption='[[6h2s]], [[Resolution|resolution]] 2.17Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6h2s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6H2S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6H2S FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.17Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=IPA:ISOPROPYL+ALCOHOL'>IPA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PYR:PYRUVIC+ACID'>PYR</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6h2s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6h2s OCA], [https://pdbe.org/6h2s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6h2s RCSB], [https://www.ebi.ac.uk/pdbsum/6h2s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6h2s ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KDGA_SACS2 KDGA_SACS2] Involved in the degradation of glucose and galactose via the Entner-Doudoroff pathway. Catalyzes the reversible cleavage of 2-keto-3-deoxy-6-phosphogluconate (KDPG) and 2-keto-3-deoxygluconate (KDG) forming pyruvate and glyceraldehyde 3-phosphate or glyceraldehyde, respectively. It is also able to catalyze the reversible cleavage of 2-keto-3-deoxy-6-phosphogalactonate (KDPGal) and 2-keto-3-deoxygalactonate (KDGal).<ref>PMID:15869466</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Aldolase 3D structures|Aldolase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Crennell | + | __TOC__ |
| - | [[Category: Danson | + | </StructureSection> |
| - | [[Category: Royer | + | [[Category: Large Structures]] |
| + | [[Category: Saccharolobus solfataricus]] | ||
| + | [[Category: Crennell SJ]] | ||
| + | [[Category: Danson MJ]] | ||
| + | [[Category: Royer S]] | ||
Current revision
Sulfolobus solfataricus 2-keto-3-deoxygluconate aldolase T157V/D181Q/A198L variant, pyruvate complex
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