7zmw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==14-3-3s binding to non-natural peptide 2c== | |
| - | + | <StructureSection load='7zmw' size='340' side='right'caption='[[7zmw]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7zmw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZMW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZMW FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B3S:(3R)-3-AMINO-4-HYDROXYBUTANOIC+ACID'>B3S</scene>, <scene name='pdbligand=BAL:BETA-ALANINE'>BAL</scene>, <scene name='pdbligand=KCJ:3-(1,3-thiazol-4-yl)-L-alanine'>KCJ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=PPN:PARA-NITROPHENYLALANINE'>PPN</scene>, <scene name='pdbligand=SEP:PHOSPHOSERINE'>SEP</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zmw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zmw OCA], [https://pdbe.org/7zmw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zmw RCSB], [https://www.ebi.ac.uk/pdbsum/7zmw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zmw ProSAT]</span></td></tr> |
| - | [[Category: Craenmehr | + | </table> |
| - | [[Category: Ottmann | + | == Function == |
| + | [https://www.uniprot.org/uniprot/1433S_HUMAN 1433S_HUMAN] Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity). p53-regulated inhibitor of G2/M progression. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Craenmehr FWB]] | ||
| + | [[Category: Ottmann C]] | ||
| + | [[Category: Somsen BA]] | ||
Current revision
14-3-3s binding to non-natural peptide 2c
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