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5nc6

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==Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with (E)-N-hydroxy-3-(naphthalen-1-yl)prop-2-enamide==
==Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with (E)-N-hydroxy-3-(naphthalen-1-yl)prop-2-enamide==
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<StructureSection load='5nc6' size='340' side='right' caption='[[5nc6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='5nc6' size='340' side='right'caption='[[5nc6]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5nc6]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NC6 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5nc6]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NC6 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=8SQ:3-naphthalen-1-yl-~{N}-oxidanyl-propanamide'>8SQ</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5nc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nc6 OCA], [http://pdbe.org/5nc6 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5nc6 RCSB], [http://www.ebi.ac.uk/pdbsum/5nc6 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5nc6 ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8SQ:3-naphthalen-1-yl-~{N}-oxidanyl-propanamide'>8SQ</scene>, <scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5nc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5nc6 OCA], [https://pdbe.org/5nc6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5nc6 RCSB], [https://www.ebi.ac.uk/pdbsum/5nc6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5nc6 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PGDA2_BACCR PGDA2_BACCR] Catalyzes the deacetylation of N-acetylglucosamine (GlcNAc) residues in peptidoglycan.<ref>PMID:29983281</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Andreou, A]]
 
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[[Category: Balomenou, S]]
 
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[[Category: Bouriotis, V]]
 
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[[Category: Eliopoulos, E E]]
 
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[[Category: Giastas, P]]
 
[[Category: Bacillus cereus]]
[[Category: Bacillus cereus]]
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[[Category: Ce4 fold]]
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[[Category: Large Structures]]
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[[Category: Hydrolase]]
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[[Category: Andreou A]]
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[[Category: Hydroxamate ligand]]
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[[Category: Balomenou S]]
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[[Category: Pgda]]
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[[Category: Bouriotis V]]
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[[Category: Polysaccharide deacetylase]]
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[[Category: Eliopoulos EE]]
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[[Category: Giastas P]]

Current revision

Crystal structure of the polysaccharide deacetylase Bc1974 from Bacillus cereus in complex with (E)-N-hydroxy-3-(naphthalen-1-yl)prop-2-enamide

PDB ID 5nc6

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