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5now

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==Structure of cyclophilin A in complex with pyridine-3,4-diamine==
==Structure of cyclophilin A in complex with pyridine-3,4-diamine==
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<StructureSection load='5now' size='340' side='right' caption='[[5now]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
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<StructureSection load='5now' size='340' side='right'caption='[[5now]], [[Resolution|resolution]] 1.48&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5now]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NOW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5NOW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5now]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5NOW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5NOW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=L89:pyridine-3,4-diamine'>L89</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.48&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peptidylprolyl_isomerase Peptidylprolyl isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.2.1.8 5.2.1.8] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=L89:pyridine-3,4-diamine'>L89</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5now FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5now OCA], [http://pdbe.org/5now PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5now RCSB], [http://www.ebi.ac.uk/pdbsum/5now PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5now ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5now FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5now OCA], [https://pdbe.org/5now PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5now RCSB], [https://www.ebi.ac.uk/pdbsum/5now PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5now ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN]] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
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[https://www.uniprot.org/uniprot/PPIA_HUMAN PPIA_HUMAN] PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5now" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5now" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Cyclophilin 3D structures|Cyclophilin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Peptidylprolyl isomerase]]
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[[Category: Homo sapiens]]
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[[Category: Georgiou, C]]
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[[Category: Large Structures]]
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[[Category: Ioannidis, H]]
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[[Category: Georgiou C]]
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[[Category: Julien, M]]
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[[Category: Ioannidis H]]
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[[Category: Mcnae, I W]]
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[[Category: Julien M]]
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[[Category: Walkinshaw, M D]]
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[[Category: Mcnae IW]]
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[[Category: Beta barrel]]
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[[Category: Walkinshaw MD]]
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[[Category: Cytosolic]]
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[[Category: Isomerase]]
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[[Category: Ligand complex]]
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[[Category: Prolyl cis/trans isomerase]]
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Current revision

Structure of cyclophilin A in complex with pyridine-3,4-diamine

PDB ID 5now

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