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RNA polymerase 3D structures
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**[[1go3]] – MjRNAP subunit RPB4, RPB7 - ''Methanocaldococcus jannaschii''<br /> | **[[1go3]] – MjRNAP subunit RPB4, RPB7 - ''Methanocaldococcus jannaschii''<br /> | ||
**[[1iw7]], [[1smy]], [[6asg]] - TtRNAP subunits α,β,β',ω ''Thermus thermophilus''<br /> | **[[1iw7]], [[1smy]], [[6asg]] - TtRNAP subunits α,β,β',ω ''Thermus thermophilus''<br /> | ||
| + | **[[8hsh]] - TtRNAP subunits α,β,β',ω - Cryo EM<br /> | ||
**[[1doq]] - TtRNAP subunit α<br /> | **[[1doq]] - TtRNAP subunit α<br /> | ||
**[[3lti]]– EcRNAP subunit β fragment – ''Escherichia coli''<br /> | **[[3lti]]– EcRNAP subunit β fragment – ''Escherichia coli''<br /> | ||
**[[4iqz]] - EcRNAP subunit β’<br /> | **[[4iqz]] - EcRNAP subunit β’<br /> | ||
| - | **[[3k4g]], [[1coo]] - EcRNAP subunit | + | **[[3k4g]], [[1coo]] - EcRNAP subunit α<br /> |
**[[1bdf]] - EcRNAP subunit α mutant) <br /> | **[[1bdf]] - EcRNAP subunit α mutant) <br /> | ||
**[[3lu0]] - EcRNAP subunits α,β,β',ω – Electron diffraction<br /> | **[[3lu0]] - EcRNAP subunits α,β,β',ω – Electron diffraction<br /> | ||
| Line 21: | Line 22: | ||
**[[1qyp]] – RNAP II C terminal – ''Thermococcus celer'' – NMR<br /> | **[[1qyp]] – RNAP II C terminal – ''Thermococcus celer'' – NMR<br /> | ||
**[[4kbj]] – MtuRNAP β subunit – ''Mycobacterium tuberculosis''<br /> | **[[4kbj]] – MtuRNAP β subunit – ''Mycobacterium tuberculosis''<br /> | ||
| - | **[[5uh7]] - MtuRNAP subunit | + | **[[5uh7]] - MtuRNAP subunit β’<br /> |
| + | **[[7z8q]] - MtuRNAP subunits α,β,β’,ω – Cryo EM<br /> | ||
**[[4noi]] – RNAP α subunit – ''Campylobacter jejuni''<br /> | **[[4noi]] – RNAP α subunit – ''Campylobacter jejuni''<br /> | ||
**[[1hqm]] – TaRNAP subunits α,β,β',ω ''Thermus aquaticus''<br /> | **[[1hqm]] – TaRNAP subunits α,β,β',ω ''Thermus aquaticus''<br /> | ||
| Line 36: | Line 38: | ||
**[[4qjv]] - TkRNAP subunits d+l<br /> | **[[4qjv]] - TkRNAP subunits d+l<br /> | ||
**[[6eyd]], [[6f6w]] – MsRNAP subunits α,β,β',ω - ''Mycobacterium smegmatis'' – Cryo EM<br /> | **[[6eyd]], [[6f6w]] – MsRNAP subunits α,β,β',ω - ''Mycobacterium smegmatis'' – Cryo EM<br /> | ||
| - | **[[6vr4]] – RNAP – Cellulophaga phage | + | **[[6vr4]] – RNAP – Cellulophaga phage φ<br /> |
**[[7ccg]] - RNAP subunit δ - ''Streptomyces albulus''<br /> | **[[7ccg]] - RNAP subunit δ - ''Streptomyces albulus''<br /> | ||
| + | **[[7ok0]], [[7oqy]] – SaRNAP – ''Sulfolobus acidocaldarius'' – Cryo EM<br /> | ||
| + | **[[8h02]] – SeRNAP subunit – ''Synechococcus elongatus''<br /> | ||
| + | **[[8emb]] – RNAP subunit ’ si3 domain – ''Thermosynechococcus vestitus''<br /> | ||
| + | **[[8dkc]] – RNAP subunits α,β,β',ω - ''Porphyromonas gingivalis'' – Cryo EM<br /> | ||
| - | *Prokaryotic DNA-dependent RNAP complex with DNA/RNA | + | *Prokaryotic DNA-dependent RNAP complex with DNA/RNA or elongation complex |
**[[4v8s]] – SsRNAP + DNA<br /> | **[[4v8s]] – SsRNAP + DNA<br /> | ||
**[[3q22]], [[3q23]], [[3q24]], [[4ff1]], [[4ff2]], [[4ff3]], [[4ff4]] – RNAP + DNA – Enterobacteria phage N4<br /> | **[[3q22]], [[3q23]], [[3q24]], [[4ff1]], [[4ff2]], [[4ff3]], [[4ff4]] – RNAP + DNA – Enterobacteria phage N4<br /> | ||
| - | **[[2o5i]], [[2o5j]], [[4gzy]], [[4gzz]], [[4xln]], [[4xlr]] | + | **[[2o5i]], [[2o5j]], [[4gzy]], [[4gzz]], [[4xln]], [[4xlr]] – TtRNAP subunits α,β,β',ω + DNA +RNA<br /> |
| - | **[[6m6c]] - TtRNAP | + | **[[6m6c]], [[8hsg]], [[8hsr]] - TtRNAP in elongation complex – Cryo EM<br /> |
**[[5x22]] - TtRNAP subunits α,β,β',ω + DNA + RNA + CMPCPP<br /> | **[[5x22]] - TtRNAP subunits α,β,β',ω + DNA + RNA + CMPCPP<br /> | ||
**[[5x21]] - TtRNAP subunits α,β,β',ω + DNA + RNA + antibiotic<br /> | **[[5x21]] - TtRNAP subunits α,β,β',ω + DNA + RNA + antibiotic<br /> | ||
**[[4wqs]], [[4xlp]], [[4xlq]], [[4xls]], [[5tjg]] - TtRNAP subunits α,β,β',ω + DNA<br /> | **[[4wqs]], [[4xlp]], [[4xlq]], [[4xls]], [[5tjg]] - TtRNAP subunits α,β,β',ω + DNA<br /> | ||
**[[2ppb]] - TtRNAP subunits α,β,β',ω + antibiotic + DNA + RNA + substrate analog<br /> | **[[2ppb]] - TtRNAP subunits α,β,β',ω + antibiotic + DNA + RNA + substrate analog<br /> | ||
| - | **[[4yg2]], [[4jk1]], [[4jk2]], [[4jkr]], [[4kmu]] - EcRNAP subunits α,β,β',ω RNA<br /> | + | **[[4yg2]], [[4jk1]], [[4jk2]], [[4jkr]], [[4kmu]] - EcRNAP subunits α,β,β',ω + RNA<br /> |
| - | **[[6flp]], [[6bjs]], [[6asx]], [[6alh]], [[6alf]], [[6rip]], [[6ri9]] - EcRNAP subunits α,β,β',ω RNA + DNA – Cryo EM<br /> | + | **[[8aby]], [[8ac0]], [[8acp]], [[8ad1]] - EcRNAP in elongation complex + RNA putL – Cryo EM<br /> |
| - | **[[ | + | **[[6flp]], [[6bjs]], [[6asx]], [[6alh]], [[6alf]], [[6rip]], [[6ri9]], [[7q0j]], [[7q0k]], [[7tyb]], [[7xue]], [[7xug]], [[7yp9]], [[8abz]], [[8ac1]], [[8ac2]], [[8eg7]], [[8eg8]], [[8egb]], [[8eh8]] , [[8eh9]], [[8eha]], [[8ehf]], [[8ehi]], [[8f1i]], [[8f1k]], [[8f3c]], [[8fix]], [[8fiy]], [[8fvr]], [[8fvw]], [[8g00]], [[8g1s]], [[8g2w]], [[8g7e]], [[8pbl]] - EcRNAP in elongation complex – Cryo EM<br /> |
| - | **[[ | + | **[[7ypa]] - EcRNAP in transcription-termination complex – Cryo EM<br /> |
| + | **[[6rh3]] - EcRNAP subunits α,β,β',ω + RNA + DNA + GMP + CTP – Cryo EM<br /> | ||
| + | **[[4kn4]], [[4kn7]] - EcRNAP subunits α,β,β',ω + RNA + antibiotic<br /> | ||
| + | **[[6vvv]] – MsRNAP in translation initiation complex <br /> | ||
| + | **[[7p5x]] – MsRNAP in translation initiation complex + PafBC – Cryo EM<br /> | ||
| + | **[[6vvx]], [[6vvy]], [[6vvs]], [[6vvt]], [[6vvz]] – MsRNAP subunits α,β,β',ω + DNA + antibiotic<br /> | ||
| + | **[[7l7b]] – RNAP subunits α,β,β',ω + sigma factor SIGA + antibiotic – ''Clostridia difficalis'' – Cryo EM<br /> | ||
| + | **[[8gzg]], [[8gzh]] – RNAP elongation complex + sigma factor SIGA – ''Synechocystic'' – Cryo EM<br /> | ||
*''Prokaryotic DNA-dependent RNAP complex with protein'' | *''Prokaryotic DNA-dependent RNAP complex with protein'' | ||
| - | **[[3p8b]] – PfRNAP subunit ε’’ + | + | **[[3p8b]] – PfRNAP subunit ε’’ + NusG <br /> |
| - | **[[3qqc]] - PfRNAP subunits β, ε’’ + | + | **[[3qqc]] - PfRNAP subunits β, ε’’ + NusG<br /> |
**[[2be5]]- TtRNAP subunits α,β,β’,ω + σ factor + inhibitor <br /> | **[[2be5]]- TtRNAP subunits α,β,β’,ω + σ factor + inhibitor <br /> | ||
**[[2cw0]], [[5tmf]] - TtRNAP subunits α,β,β’,ω + σ factor<br /> | **[[2cw0]], [[5tmf]] - TtRNAP subunits α,β,β’,ω + σ factor<br /> | ||
| Line 66: | Line 79: | ||
**[[5xj0]] - TtRNAP subunits α,β,β’,ω + σ factor + GP39 + GP76<br /> | **[[5xj0]] - TtRNAP subunits α,β,β’,ω + σ factor + GP39 + GP76<br /> | ||
**[[4wqt]] - TtRNAP subunits α,β,β’,ω + RNA cleavage stimulating factor<br /> | **[[4wqt]] - TtRNAP subunits α,β,β’,ω + RNA cleavage stimulating factor<br /> | ||
| + | **[[8hsl]] - TtRNAP subunits α,β,β’,ω + transcription termination factor rho – Cryo EM<br /> | ||
**[[3mlq]] - TtRNAP subunit β + transcription-repair coupling factor<br /> | **[[3mlq]] - TtRNAP subunit β + transcription-repair coupling factor<br /> | ||
**[[3woe]], [[3wof]] - TtRNAP subunit β + GP39<br /> | **[[3woe]], [[3wof]] - TtRNAP subunit β + GP39<br /> | ||
**[[2lmc]] - EcRNAP subunit β + RNAP inhibitor <br /> | **[[2lmc]] - EcRNAP subunit β + RNAP inhibitor <br /> | ||
**[[3mmp]] - EcRNAP subunit β + EF-TU<br /> | **[[3mmp]] - EcRNAP subunit β + EF-TU<br /> | ||
| - | **[[4ljz]], [[4lk1]], [[4mey]], [[4xsx]], [[4xsy]], [[4xsz]], [[4zh2]], [[4zh3]] , [[4zh4 | + | **[[7egs]] - EcRNAP subunit β + DNA helicase II 654-720<br /> |
| + | **[[4ljz]], [[4lk1]], [[4mey]], [[4xsx]], [[4xsy]], [[4xsz]], [[4zh2]], [[4zh3]] , [[4zh4]], [[5nwt]], [[5uag]], [[5uah]], [[5uaj]], [[5ual]], [[5uaq]], [[5ui8]] - EcRNAP subunits α,β,β’,ω + σ factor <br /> | ||
**[[6c9y]] - EcRNAP subunits α,β,β’,ω + σ factor – Cryo EM<br /> | **[[6c9y]] - EcRNAP subunits α,β,β’,ω + σ factor – Cryo EM<br /> | ||
**[[4mex]] - EcRNAP subunits α,β,β’,ω + σ factor + salinamide<br /> | **[[4mex]] - EcRNAP subunits α,β,β’,ω + σ factor + salinamide<br /> | ||
| Line 78: | Line 93: | ||
**[[5w1s]] - EcRNAP subunits α,β,β’,ω + σ factor + TRAR<br /> | **[[5w1s]] - EcRNAP subunits α,β,β’,ω + σ factor + TRAR<br /> | ||
**[[6p1k]] - EcRNAP subunits α,β,β’,ω + RPOD – Cryo EM<br /> | **[[6p1k]] - EcRNAP subunits α,β,β’,ω + RPOD – Cryo EM<br /> | ||
| + | **[[7xui]] – EcRNAP in elongation complex + RPOD – Cryo EM<br /> | ||
**[[6vjs]] - EcRNAP subunits α,β,β’,ω + RPOD + inhibitor<br /> | **[[6vjs]] - EcRNAP subunits α,β,β’,ω + RPOD + inhibitor<br /> | ||
**[[6r9b]], [[6r9g]] - EcRNAP subunits α,β,β’,ω + OCR – Cryo EM<br /> | **[[6r9b]], [[6r9g]] - EcRNAP subunits α,β,β’,ω + OCR – Cryo EM<br /> | ||
**[[6n57]], [[6n58]] - EcRNAP subunits α,β,β’,ω + RPOD + TRAR – Cryo EM<br /> | **[[6n57]], [[6n58]] - EcRNAP subunits α,β,β’,ω + RPOD + TRAR – Cryo EM<br /> | ||
| - | **[[ | + | **[[7w5y]] - EcRNAP subunits α,β,β’,ω + RPOD + SoxS – Cryo EM<br /> |
| + | **[[7w5w]] - EcRNAP subunits α,β,β’,ω + RPOD + SoxS + micF DNA – Cryo EM<br /> | ||
| + | **[[7w5x]] - EcRNAP subunits α,β,β’,ω + RPOD + SoxS + zwf DNA – Cryo EM<br /> | ||
**[[5tbz]] - EcRNAP subunits α,β,β’ + NusG – Cryo EM<br /> | **[[5tbz]] - EcRNAP subunits α,β,β’ + NusG – Cryo EM<br /> | ||
| + | **[[6xln]], [[7mko]] - EcRNAP in elongation complex – Cryo EM<br /> | ||
| + | **[[7mkp]] - EcRNAP core – Cryo EM<br /> | ||
| + | **[[7m8e]], [[7mkn]], [[7mkq]] - EcRNAP subunits α,β,β’,ω + RapA – Cryo EM<br /> | ||
**[[6fbv]] - MtuRNAP subunits α,β,β’,ω + σ factor – single particle EM<br /> | **[[6fbv]] - MtuRNAP subunits α,β,β’,ω + σ factor – single particle EM<br /> | ||
| - | **[[ | + | **[[7u22]] - MtuRNAP subunits α,β,β’,ω + σ factor SIGA<br /> |
| - | **[[ | + | **[[7pp4]], [[7q4u]], [[7q59]], [[7zf2]] - MtuRNAP subunits α,β,β’,ω + σ factor SIGB – Cryo EM<br /> |
| - | **[[ | + | **[[5zx3]] - MtuRNAP subunits α,β,β’,ω + σ factor SIGH<br /> |
**[[3ihq]], [[1z3e]], [[3gfk]] - BsRNAP subunit α + regulatory protein SPX<br /> | **[[3ihq]], [[1z3e]], [[3gfk]] - BsRNAP subunit α + regulatory protein SPX<br /> | ||
**[[1l9u]] - TaRNAP subunits α,β,β’,ω + σ factor<br /> | **[[1l9u]] - TaRNAP subunits α,β,β’,ω + σ factor<br /> | ||
| - | **[[2jzb]] – RNAP subunit α + NusA | + | **[[2jzb]] – RNAP subunit α + NusA – ''Yersinia pseudotuberculosis''<br /> |
**[[3tbi]] - RNAP subunit β + GP33 – Enterobacteria phage T4<br /> | **[[3tbi]] - RNAP subunit β + GP33 – Enterobacteria phage T4<br /> | ||
| - | **[[3lpe ]]- MjRNAP subunit ε’’ + | + | **[[3lpe]] - MjRNAP subunit ε’’ + NusG<br /> |
**[[6eyd]] - MsRNAP subunits α,β,β’,ω + σ factor – Cryo EM<br /> | **[[6eyd]] - MsRNAP subunits α,β,β’,ω + σ factor – Cryo EM<br /> | ||
| + | **[[6yxu]], [[6yys]], [[6z11]] - MsRNAP subunits α,β,β’,ω + HelD – Cryo EM<br /> | ||
**[[6kf4]] – TkRNAP subunits a’+d+e’+f+h+k+l+n+p + transcription factor E – Cryo EM<br /> | **[[6kf4]] – TkRNAP subunits a’+d+e’+f+h+k+l+n+p + transcription factor E – Cryo EM<br /> | ||
| - | **[[6zfb]] - BsRNAP subunits α,β,β’, | + | **[[6wvk]], [[6zca]], [[6zfb]] - BsRNAP subunits α,β,β’,d + HelD – Cryo EM<br /> |
| + | **[[7oq4]] - SaRNAP + viral RNAP inhibitory protein – Cryo EM<br /> | ||
*''Prokaryotic DNA-dependent RNAP complex with σ factor + DNA/RNA'' | *''Prokaryotic DNA-dependent RNAP complex with σ factor + DNA/RNA'' | ||
| - | **[[6lts]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA<br /> | + | **[[6lts]] - TtRNAP subunits α,β,β’,ω + σ factor SIGA + DNA<br /> |
| + | **[[7qxi]] - TtRNAP subunits α,β,β’,ω + σ factor-54 + DNA – Cryo EM<br /> | ||
| + | **[[7mlb]], [[7mli]], [[7mlj]], [[7rdq]] - TtRNAP in elongation complex + σ factor SIGA – Cryo EM<br /> | ||
**[[4oin]], [[4oio]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA<br /> | **[[4oin]], [[4oio]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA<br /> | ||
**[[4oip]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + nucleotide<br /> | **[[4oip]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + nucleotide<br /> | ||
**[[4oiq]], [[4oir]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + antibiotic<br /> | **[[4oiq]], [[4oir]] - TtRNAP subunits α,β,β’,ω + σ factor + GE23077 + DNA + antibiotic<br /> | ||
**[[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[5d4d]], [[5d4e]], [[5voi]], [[6p70]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA<br /> | **[[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[5d4d]], [[5d4e]], [[5voi]], [[6p70]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA<br /> | ||
| - | **[[4q5s]], [[5d4c]], [[5e17]], [[5e18]], [[5vo8]], [[6p71]], [[6oy7]], [[6oy6]], [[6oy5]], [[6ow3]], [[6ovy]], [[6ovr]], [[6kqd]], [[6kqe]], [[6kqf]], [[6kqg]], [[6kqh]], [[6kql]], [[6kqm]], [[6kqn]], [[6l74]] - TtRNAP | + | **[[4q5s]], [[5d4c]], [[5e17]], [[5e18]], [[5vo8]], [[6p71]], [[6oy7]], [[6oy6]], [[6oy5]], [[6ow3]], [[6ovy]], [[6ovr]], [[6kqd]], [[6kqe]], [[6kqf]], [[6kqg]], [[6kqh]], [[6kql]], [[6kqm]], [[6kqn]], [[6l74]] - TtRNAP in elongation complex<br /> |
**[[5i2d]] - TtRNAP subunits α,β,β’,ω + σ factor + transcriptional regulator + DNA + RNA<br /> | **[[5i2d]] - TtRNAP subunits α,β,β’,ω + σ factor + transcriptional regulator + DNA + RNA<br /> | ||
**[[6cuu]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA + antibiotic<br /> | **[[6cuu]] - TtRNAP subunits α,β,β’,ω + σ factor + DNA + antibiotic<br /> | ||
| Line 109: | Line 134: | ||
**[[6n61]] - EcRNAP subunits α,β,β’,ω + σ factor + DNA + capistruin peptide<br /> | **[[6n61]] - EcRNAP subunits α,β,β’,ω + σ factor + DNA + capistruin peptide<br /> | ||
**[[6n60]] - EcRNAP subunits α,β,β’,ω + σ factor + DNA + microcin peptide<br /> | **[[6n60]] - EcRNAP subunits α,β,β’,ω + σ factor + DNA + microcin peptide<br /> | ||
| - | **[[5nsr]], [[5nss]], [[6gh6]], [[6gh5]], [[6ca0]], [[6omf]] - EcRNAP subunits α,β,β’,ω + σ factor + DNA – Cryo EM<br /> | + | **[[5nsr]], [[5nss]], [[6gh6]], [[6gh5]], [[6ca0]], [[6omf]], [[7mkd]], [[7mke]], [[7mki]], [[7mkj]] - EcRNAP subunits α,β,β’,ω + σ factor + DNA – Cryo EM<br /> |
**[[5vt0]] - EcRNAP subunits α,β,β’,ω + σ factor + RNA – Cryo EM<br /> | **[[5vt0]] - EcRNAP subunits α,β,β’,ω + σ factor + RNA – Cryo EM<br /> | ||
**[[4yln]], [[4ylo]], [[4ylp]], [[5ipl]], [[5ipm]], [[5ipn]], [[6gfw]] - EcRNAP subunits α,β,β’,ω + σ factor + DNA + RNA<br /> | **[[4yln]], [[4ylo]], [[4ylp]], [[5ipl]], [[5ipm]], [[5ipn]], [[6gfw]] - EcRNAP subunits α,β,β’,ω + σ factor + DNA + RNA<br /> | ||
**[[6b6h]] - EcRNAP subunits α,β,β’,ω + σ factor + CAP + DNA + RNA – Cryo EM<br /> | **[[6b6h]] - EcRNAP subunits α,β,β’,ω + σ factor + CAP + DNA + RNA – Cryo EM<br /> | ||
| - | **[[6k4y]] - EcRNAP subunits α,β,β’,ω + σ factor + | + | **[[8hkc]] - EcRNAP subunits α,β,β’ + σ factor RPOH + DNA – Cryo EM<br /> |
| + | **[[6k4y]] - EcRNAP subunits α,β,β’,ω + σ factor + MTOH + DNA – Cryo EM<br /> | ||
| + | **[[7qwp]], [[8f1j]] - EcRNAP subunits α,β,β’,ω + σ factor-54 + DNA – Cryo EM<br /> | ||
| + | **[[7q9v]] - EcRNAP subunits α,β,β’,ω + σ factor-54 + PspF + DNA – Cryo EM<br /> | ||
**[[3iyd]] - EcRNAP subunits α,β,β’,ω + σ factor + catabolite gene activator + DNA<br /> | **[[3iyd]] - EcRNAP subunits α,β,β’,ω + σ factor + catabolite gene activator + DNA<br /> | ||
**[[4s20]] - EcRNAP subunits α,β,β’,ω + σ factor + RAPA + DNA<br /> | **[[4s20]] - EcRNAP subunits α,β,β’,ω + σ factor + RAPA + DNA<br /> | ||
| - | **[[5ms0]] - EcRNAP subunits α,β,β’,ω + σ factor + NusB + NusG + NusA | + | **[[5ms0]] - EcRNAP subunits α,β,β’,ω + σ factor + NusB + NusG + NusA + RS10 + DNA – Cryo EM<br /> |
| - | **[[5uha]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA <br /> | + | **[[5uha]], [[6vw0]], [[7rwi]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA <br /> |
**[[5uh9]], [[5uh8]], [[6jcy]], [[6jcx]], [[6jbq]], [[6kon]], [[6koo]], [[6kop]], [[6koq]], [[6tye]], [[6tyf]], [[6tyg]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA <br /> | **[[5uh9]], [[5uh8]], [[6jcy]], [[6jcx]], [[6jbq]], [[6kon]], [[6koo]], [[6kop]], [[6koq]], [[6tye]], [[6tyf]], [[6tyg]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA <br /> | ||
| + | **[[8e8m]], [[8e95]] - MtuRNAP in elongation complex <br /> | ||
| + | **[[8hih]] - MtuRNAP in elongation complex + GlnR – Cryo EM<br /> | ||
**[[5uhg]], [[5uhc]], [[5uh6]], [[5uh5]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA + antibiotic<br /> | **[[5uhg]], [[5uhc]], [[5uh6]], [[5uh5]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA + antibiotic<br /> | ||
**[[5uhd]], [[5uhb]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + antibiotic<br /> | **[[5uhd]], [[5uhb]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + antibiotic<br /> | ||
**[[5uhf]], [[5uhe]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA + inhibitor<br /> | **[[5uhf]], [[5uhe]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA + inhibitor<br /> | ||
**[[1l9z]] - TaRNAP subunits α,β,β’,ω + σ factor + DNA<br /> | **[[1l9z]] - TaRNAP subunits α,β,β’,ω + σ factor + DNA<br /> | ||
| + | **[[8i23]], [[8i24]] - RNAP subunits α,β,β’,ω + σ factor SIGI1 + DNA – ''Clostridium thermocellum'' - Cryo EM<br /> | ||
*''Prokaryotic DNA-dependent RNAP complex with protein + DNA/RNA'' | *''Prokaryotic DNA-dependent RNAP complex with protein + DNA/RNA'' | ||
**[[3aoh]], [[3aoi]] - TtRNAP subunits α,β,β’,ω + DNA + RNA + GFH1<br /> | **[[3aoh]], [[3aoi]] - TtRNAP subunits α,β,β’,ω + DNA + RNA + GFH1<br /> | ||
| - | **[[6wox]], [[6woy]] - TtRNAP subunits α,β,β’,ω in transcription complex<br /> | + | **[[6wox]], [[6woy]], [[7eh0]], [[7eh1]], [[7eh2]] - TtRNAP subunits α,β,β’,ω in transcription complex<br /> |
**[[6m6a]], [[6m6b]] - TtRNAP subunits α,β,β’,ω + transcription-repair-coupling factor + DNA – Cryo EM<br /> | **[[6m6a]], [[6m6b]] - TtRNAP subunits α,β,β’,ω + transcription-repair-coupling factor + DNA – Cryo EM<br /> | ||
**[[3t72]] - EcRNAP subunit β + Pho box DNA + PhoB<br /> | **[[3t72]] - EcRNAP subunit β + Pho box DNA + PhoB<br /> | ||
| Line 134: | Line 165: | ||
**[[5ciz]] - EcRNAP subunit α + DNA + CRP<br /> | **[[5ciz]] - EcRNAP subunit α + DNA + CRP<br /> | ||
**[[3n97]] - EcRNAP subunit α C terminal + DNA + σ factor<br /> | **[[3n97]] - EcRNAP subunit α C terminal + DNA + σ factor<br /> | ||
| + | **[[6z9p]], [[6z9q]], [[6z9r]], [[6z9s]], [[6z9t]], [[7add]], [[7ade]] - EcRNAP in termination transcription complex<br /> | ||
| + | **[[6vyu]] - EcRNAP in transcription initiation complex + mRNA<br /> | ||
**[[6c6u]] - EcRNAP subunits α,β,β’,ω + NusG + DNA – Cryo EM<br /> | **[[6c6u]] - EcRNAP subunits α,β,β’,ω + NusG + DNA – Cryo EM<br /> | ||
| + | **[[6vu3]], [[6vz3]] - EcRNAP transcription translation complex + mRNA – Cryo EM<br /> | ||
| + | **[[6vzj]] - EcRNAP transcription translation complex + mRNA + tRNA – Cryo EM<br /> | ||
| + | **[[6vyz]] - EcRNAP transcription translation complex + NusA + mRNA + tRNA – Cryo EM<br /> | ||
| + | **[[6vyq]], [[6vyr]], [[6vys]], [[6vyt]], [[6vyw]], [[6vyx]], [[6vyy]], [[6vz2]], [[6vz5]], [[6vz7]], [[6xdr]], [[6xgf]], [[6xij]], [[6xii]] - EcRNAP transcription translation complex + NusG + mRNA + tRNA – Cryo EM<br /> | ||
| + | **[[6x6t]], [[6x7f]], [[6x7k]], [[6x9q]], [[6xdq]] - EcRNAP transcription translation complex + NusA + NusG + mRNA + tRNA – Cryo EM<br /> | ||
**[[6c6t]], [[6c6s]] - EcRNAP subunits α,β,β’,ω + RFAH + DNA – Cryo EM<br /> | **[[6c6t]], [[6c6s]] - EcRNAP subunits α,β,β’,ω + RFAH + DNA – Cryo EM<br /> | ||
| - | **[[6gov]] - EcRNAP subunits α,β,β’,ω + NusB + | + | **[[6gov]] - EcRNAP subunits α,β,β’,ω + NusB + NusG + RS10 + DNA – Cryo EM<br /> |
**[[6flq]] - EcRNAP subunits α,β,β’,ω + NusA + DNA + RNA – Cryo EM<br /> | **[[6flq]] - EcRNAP subunits α,β,β’,ω + NusA + DNA + RNA – Cryo EM<br /> | ||
| + | **[[6xas]] - EcRNAP subunits α,β,β’,ω + NusA + helicase rho + DNA + RNA – Cryo EM<br /> | ||
| + | **[[6xav]], [[7adb]], [[7adc]] - EcRNAP subunits α,β,β’,ω + NusG + helicase rho + DNA + RNA – Cryo EM<br /> | ||
**[[6alg]] - EcRNAP subunits α,β,β’,ω + NUN + DNA + RNA – Cryo EM<br /> | **[[6alg]] - EcRNAP subunits α,β,β’,ω + NUN + DNA + RNA – Cryo EM<br /> | ||
**[[6p19]] - EcRNAP subunits α,β,β’,ω + protein Q + DNA + RNA – Cryo EM<br /> | **[[6p19]] - EcRNAP subunits α,β,β’,ω + protein Q + DNA + RNA – Cryo EM<br /> | ||
| Line 143: | Line 183: | ||
**[[6p18]] - EcRNAP subunits α,β,β’,ω + protein Q + σ factor + DNA + RNA – Cryo EM<br /> | **[[6p18]] - EcRNAP subunits α,β,β’,ω + protein Q + σ factor + DNA + RNA – Cryo EM<br /> | ||
**[[6kj6]] - EcRNAP subunits α,β,β’,ω + RPOS + σ factor-binding protein CRL + DNA + RNA – Cryo EM<br /> | **[[6kj6]] - EcRNAP subunits α,β,β’,ω + RPOS + σ factor-binding protein CRL + DNA + RNA – Cryo EM<br /> | ||
| - | **[[6n4c]], [[6oul]], [[ | + | **[[7chw]], [[8igs]] - EcRNAP subunits α,β,β’,ω + σ factor-binding protein PROD + DNA – Cryo EM<br /> |
| + | **[[6x26]], [[6x2f]], [[6x2n]], [[6x43]], [[6x4w]], [[6x4y]], [[6x50]] - EcRNAP in elongation complex + TRCF – Cryo EM<br /> | ||
| + | **[[8e3f]], [[8e6x]], [[8e6z]] - EcRNAP in elongation complex + NusG - Cryo EM<br /> | ||
| + | **[[8g4w]], [[8g8z]] - EcRNAP in elongation complex + preQ1 – Cryo EM<br /> | ||
| + | **[[7uwe]] - EcRNAP in elongation complex + RNase HII – Cryo EM<br /> | ||
| + | **[[8igr]] - EcRNAP in transcription activation complex + phage regulatory protein CII - Cryo EM<br /> | ||
| + | **[[7vwz]] - EcRNAP in transcription activation complex + NusA + antitermination protein - Cryo EM<br /> | ||
| + | **[[7ubm]], [[7ubn]] - EcRNAP in transcription antitermination complex + right origin binding protein - Cryo EM<br /> | ||
| + | **[[7khb]], [[7khc]], [[7khe]], [[7khi]] - EcRNAP subunits α,β,β’,ω + σ factor RPOD + DNAK suppressor protein + DNA – Cryo EM<br /> | ||
| + | **[[7bef]], [[7beg]] - EcRNAP subunits α,β,β’,ω + σ factor RPOD + RAMA + DNA – Cryo EM<br /> | ||
| + | **[[6xh7]], [[7c17]] - EcRNAP subunits α,β,β’,ω + σ factor RPOD + CueR + DNA – Cryo EM<br /> | ||
| + | **[[6xh8]] - EcRNAP subunits α,β,β’,ω + σ factor RPOD + CueR + DNA + RNA – Cryo EM<br /> | ||
| + | **[[6xl5]], [[6xl9]], [[6xlj]], [[6xll]], [[6xlm]] - EcRNAP subunits α,β,β’,ω + σ factor RPOD + DNA + RNA – Cryo EM<br /> | ||
| + | **[[6wmu]], [[7c97]], [[7dy6]] - EcRNAP subunits α,β,β’,ω + σ factor RPOD + starvation protein + DNA - Cryo EM<br /> | ||
| + | **[[7d7c]] - EcRNAP subunits α,β,β’,ω + GP55 + DNA - Cryo EM<br /> | ||
| + | **[[7d7d]] - EcRNAP subunits α,β,β’,ω + DNAP clamp + GP55 + DNA - Cryo EM<br /> | ||
| + | **[[6n4c]], [[6oul]], [[7khc]], [[7khb]], [[7n4e]] - EcRNAP subunits α,β,β’,ω + RPOD + DNA – Cryo EM<br /> | ||
| + | **[[7szj]], [[7szk]] - EcRNAP subunits α,β,β’,ω + RPOD + DNA + drug – Cryo EM<br /> | ||
**[[6ldi]] - EcRNAP subunits α,β,β’,ω + RPOD + CUER + DNA + RNA – Cryo EM<br /> | **[[6ldi]] - EcRNAP subunits α,β,β’,ω + RPOD + CUER + DNA + RNA – Cryo EM<br /> | ||
**[[6pb4]], [[6pb5]], [[6pb6]] - EcRNAP subunits α,β,β’,ω + RPOD + CRP + DNA + RNA – Cryo EM<br /> | **[[6pb4]], [[6pb5]], [[6pb6]] - EcRNAP subunits α,β,β’,ω + RPOD + CRP + DNA + RNA – Cryo EM<br /> | ||
| Line 151: | Line 208: | ||
**[[6tqn]], [[6tqo]] - EcRNAP subunits α,β,β’,ω in anti-termination complex – Cryo EM<br /> | **[[6tqn]], [[6tqo]] - EcRNAP subunits α,β,β’,ω in anti-termination complex – Cryo EM<br /> | ||
**[[7c17]] - EcRNAP subunits α,β,β’,ω in transcription complex – Cryo EM<br /> | **[[7c17]] - EcRNAP subunits α,β,β’,ω in transcription complex – Cryo EM<br /> | ||
| + | **[[7py3]], [[7pyj]], [[7pyk]] - EcRNAP in elongation complex + NusA - Cryo EM<br /> | ||
| + | **[[7py0]], [[7py1]], [[7py8]] - EcRNAP in elongation complex + NusG - Cryo EM<br /> | ||
| + | **[[7py5]], [[7py6]], [[7py7]] - EcRNAP in elongation complex + NusG + NusA - Cryo EM<br /> | ||
| + | **[[8e5k]], [[8e5o]] - EcRNAP in transcription pre-termination complex + NusG - Cryo EM<br /> | ||
**[[7c97]], [[7chw]] - EcRNAP subunits α,β,β’,ω in promoter-open complex – Cryo EM<br /> | **[[7c97]], [[7chw]] - EcRNAP subunits α,β,β’,ω in promoter-open complex – Cryo EM<br /> | ||
**[[6j9f]] - XoRNAP subunits α,β,β’,ω + P7 + DNA + RNA – Xanthomonas oryzae - Cryo EM<br /> | **[[6j9f]] - XoRNAP subunits α,β,β’,ω + P7 + DNA + RNA – Xanthomonas oryzae - Cryo EM<br /> | ||
| Line 157: | Line 218: | ||
**[[6dve]], [[6dvd]], [[6dvc]], [[6dvb]], [[6dv9]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA<br /> | **[[6dve]], [[6dvd]], [[6dvc]], [[6dvb]], [[6dv9]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA<br /> | ||
**[[5zx2]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA<br /> | **[[5zx2]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RNA<br /> | ||
| + | **[[7kin]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RBPA – Cryo EM<br /> | ||
| + | **[[7kif]], [[7kim]] - MtuRNAP subunits α,β,β’,ω + σ factor + DNA + RBPA + CARD + Whib7 – Cryo EM<br /> | ||
| + | **[[6wmp]] - FtRNAP subunits α,β,β’,ω + RNA + DNA – ''Francisella tularensis'' - Cryo EM<br /> | ||
| + | **[[6wmr]], [[6wmt]] - FtRNAP subunits α,β,β’,ω + σ factor-binding protein PROD + starvation protein + macrophage growth locus + DNA - Cryo EM<br /> | ||
| + | **[[6wvj]] - BsRNAP in elongation complex - Cryo EM<br /> | ||
| + | **[[7ckq]] - BsRNAP subunits α,β,β’,ω + σ factor-binding protein SIGA + multidrug regulator + YkzG + DNA - Cryo EM<br /> | ||
| + | **[[7f75]] - BsRNAP subunits α,β,β’,ω + σ factor-binding protein SIGA + regulator Spx + RNA + DNA - Cryo EM<br /> | ||
| + | **[[7ye2]] - CavRNAP in transcription activation complex – Caulobacter vibrioides - Cryo EM<br /> | ||
| + | **[[7ye1]] - CavRNAP in transcription activation complex + GCRA - Cryo EM<br /> | ||
| + | **[[7xya]], [[7xyb]] – PaRNAP subunits α,β,β’,ω + AlpA peptide + RNA + DNA – ''Pseudomonas aeruginosa'' <br /> | ||
| + | **[[7xyb]] – PaRNAP subunits α,β,β’,ω + sigma factor RPOS – Cryo EM<br /> | ||
| + | **[[7f0r]], [[7xl3]], [[7xl4]] – PaRNAP subunits α,β,β’,ω + sigma factor RPOS + SutA – Cryo EM<br /> | ||
| + | **[[8e79]] - BsRNAP in elongation complex + NusG - Cryo EM<br /> | ||
| + | **[[8e74]], [[8e82]], [[8ehq]], [[8ej3]], [[8eoe]], [[8eof]], [[8eos]], [[8eot]], [[8exy]] - MtuRNAP in elongation complex + NusG - Cryo EM<br /> | ||
| + | **[[8h3v]] - RNAP in transcription activation complex + NusG + NTCA + NTCB + VF1- Cryo EM<br /> | ||
| + | **[[8dy7]], [[8dy9]] - RNAP subunits α,β,β’,ω + σ factor + DNA + RBPA + WHIA + WHIB – Streptococcus venezuelae - Cryo EM<br /> | ||
| + | **[[8syi]] - SeRNAP in elongation complex + NusG - Cryo EM<br /> | ||
| + | **[[7vpd]], [[7vpz]], [[7x74]], [[7x75]], [[7x76]] - RNAP in elongation complex + ZUR – Streptococcus coelicolor - Cryo EM<br /> | ||
*''Prokaryotic DNA-dependent RNAP complex with small molecule'' | *''Prokaryotic DNA-dependent RNAP complex with small molecule'' | ||
| Line 165: | Line 244: | ||
*Viral DNA-dependent RNAP | *Viral DNA-dependent RNAP | ||
| - | **[[6ric]] – VvRNAP – vaccinia virus – Cryo EM<br /> | + | **[[6ric]], [[7amv]], [[7aoz]], [[7ap8]], [[7ap9]], [[7aof]], [[7aoh]] – VvRNAP – vaccinia virus – Cryo EM<br /> |
**[[6rid]] – VvRNAP + RNA + DNA – Cryo EM<br /> | **[[6rid]] – VvRNAP + RNA + DNA – Cryo EM<br /> | ||
**[[6rie]] – VvRNAP + mRNA capping enzyme + RNA + DNA – Cryo EM<br /> | **[[6rie]] – VvRNAP + mRNA capping enzyme + RNA + DNA – Cryo EM<br /> | ||
| + | **[[8fm9]], [[8fma]], [[8fmb]] – RNAP – flock house virus – Cryo EM<br /> | ||
*Eukaryotic DNA-dependent RNAP I | *Eukaryotic DNA-dependent RNAP I | ||
| + | **[[8a43]] – hRNAP I – human - Cryo EM<br /> | ||
| + | **[[7oba]] – hRNAP I + TIF-IA - Cryo EM<br /> | ||
| + | **[[7obb]] – hRNAP I + DNA – Cryo EM<br /> | ||
| + | **[[7ob9]], [[7vba]], [[7vbb]], [[7vbc]] – hRNAP I in elongation complex – Cryo EM<br /> | ||
**[[1a1d]] – yRNAP subunit RPB8 – yeast - NMR<br /> | **[[1a1d]] – yRNAP subunit RPB8 – yeast - NMR<br /> | ||
**[[2rf4]] - yRNAP I subunit RPA4<br /> | **[[2rf4]] - yRNAP I subunit RPA4<br /> | ||
| Line 178: | Line 262: | ||
**[[5w66]], [[5w65]], [[5w64]], [[5w5y]] – yRNAP I + transcription initiation factor + DNA + RNA – Cryo EM<br /> | **[[5w66]], [[5w65]], [[5w64]], [[5w5y]] – yRNAP I + transcription initiation factor + DNA + RNA – Cryo EM<br /> | ||
**[[6tps]] – yRNAP I in pre-initiation complex – Cryo EM<br /> | **[[6tps]] – yRNAP I in pre-initiation complex – Cryo EM<br /> | ||
| + | **[[7aoc]], [[7aod]], [[7aoe]] – fyRNAP I – fission yeast – Cryo EM<br /> | ||
*Eukaryotic DNA-dependent RNAP II | *Eukaryotic DNA-dependent RNAP II | ||
| - | **[[1qkl]] - hRNAP II subunit RPB6 - | + | **[[1qkl]] - hRNAP II subunit RPB6 <br /> |
| + | **[[7dth]] - hRNAP II subunit RPB6 - NMR<br /> | ||
**[[2c35]] - hRNAP II subunits RPB4 RPB7 (mutant) – NMR<br /> | **[[2c35]] - hRNAP II subunits RPB4 RPB7 (mutant) – NMR<br /> | ||
**[[2f3i]] - hRNAP II subunits RPB8 RPB17 RPABC3 – NMR<br /> | **[[2f3i]] - hRNAP II subunits RPB8 RPB17 RPABC3 – NMR<br /> | ||
**[[2ghq]], [[2ght]] - hRNAP II subunits RPB1 + hRNAP II C terminal<br /> | **[[2ghq]], [[2ght]] - hRNAP II subunits RPB1 + hRNAP II C terminal<br /> | ||
**[[2q5e]], [[3l0b]], [[3l0c]] - hRNAP II C terminal<br /> | **[[2q5e]], [[3l0b]], [[3l0c]] - hRNAP II C terminal<br /> | ||
| + | **[[7ozn]], [[8b3d]], [[8b3f]] – pRNAP II – Cryo EM<br /> | ||
| + | **[[7w82]] – cRNAP II - maize<br /> | ||
| + | **[[7w88]] – cRNAP II – Cryo EM<br /> | ||
| + | **[[7rqs]] - AtRNAP II – ''Arabidopsis thaliana'' - Cryo EM<br /> | ||
| + | **[[8h40]] – RNAP II + NtcA – ''anabaena'' – Cryo EM<br /> | ||
**[[1nik]], [[1nt9]], [[1wcm]], [[2b8k]], [[3fki]], [[3qt1]], [[1i3q]], [[1i50]], [[1dzf]], [[5ip7]], [[5ip9]], [[5u5q]] – yRNAP II<br /> | **[[1nik]], [[1nt9]], [[1wcm]], [[2b8k]], [[3fki]], [[3qt1]], [[1i3q]], [[1i50]], [[1dzf]], [[5ip7]], [[5ip9]], [[5u5q]] – yRNAP II<br /> | ||
| - | **[[ | + | **[[3j1n]], [[4v1n]], [[5fmf]], [[5x51]], [[5x50]], [[5x4z]], [[7ozo]], [[7ozp]] – yRNAP II – Cryo EM<br /> |
| - | + | **[[7ked]], [[7kee]], [[7kef]] – yRNAP II <br /> | |
| - | **[[ | + | |
**[[1y14]] - yRNAP II subunits RPB4 RPB7<br /> | **[[1y14]] - yRNAP II subunits RPB4 RPB7<br /> | ||
| - | + | **[[3ef0]], [[3ef1]] - fyRNAP II subunit α C terminal <br /> | |
| - | + | ||
| - | **[[3ef0]], [[3ef1]] - fyRNAP II subunit α C terminal | + | |
**[[3h0g]] – fyRNAP II<br /> | **[[3h0g]] – fyRNAP II<br /> | ||
| - | **[[5u0s]] – fyRNAP II + mediator complex – Cryo EM<br /> | ||
*''Eukaryotic DNA-dependent RNAP II complex with DNA/RNA'' | *''Eukaryotic DNA-dependent RNAP II complex with DNA/RNA'' | ||
| + | **[[8p4e]] - hRNAP II + RNA + DNA – Cryo EM<br /> | ||
**[[4boc]] – hRNAP + DNA<br /> | **[[4boc]] – hRNAP + DNA<br /> | ||
| + | **[[5flm]] – bRNAP II in elongation complex - bovine<br /> | ||
| + | **[[5oik]] – bRNAP II + SPT4 + SPT5 + DNA + RNA <br /> | ||
**[[1i6h]], [[4a3i]] - yRNAP II + DNA<br /> | **[[1i6h]], [[4a3i]] - yRNAP II + DNA<br /> | ||
| - | **[[4v1m]] - yRNAP II + DNA – Cryo EM<br /> | + | **[[4v1m]], [[7mka]] - yRNAP II + DNA – Cryo EM<br /> |
| - | **[[1r9s]], [[2ja5]], [[2ja6]], [[2ja7]], [[2ja8]], [[2nvq]], [[2nvt]], [[2nvx]], [[2nvy]], [[2nvz]], [[3gtg]], [[3gtj]], [[3gtk]], [[3gtl]], [[3gtm]], [[3gto]], [[3gtp]], [[3gtq]], [[3hov]], [[3how]], [[3hox]], [[3hoy]], [[3hoz]], [[3po2]], [[3po3]], [[3m3y]], [[3m4o]], [[4a3g]], [[4a93]], [[4a3b]], [[4a3c]], [[4a3d]], [[4a3e]], [[4a3f]], [[4a3j]], [[4a3k]], [[4a3l]], [[4a3m]] - yRNAP II + RNA + DNA<br /> | + | **[[1r9s]], [[2ja5]], [[2ja6]], [[2ja7]], [[2ja8]], [[2nvq]], [[2nvt]], [[2nvx]], [[2nvy]], [[2nvz]], [[3gtg]], [[3gtj]], [[3gtk]], [[3gtl]], [[3gtm]], [[3gto]], [[3gtp]], [[3gtq]], [[3hov]], [[3how]], [[3hox]], [[3hoy]], [[3hoz]], [[3po2]], [[3po3]], [[3m3y]], [[3m4o]], [[4a3g]], [[4a93]], [[4a3b]], [[4a3c]], [[4a3d]], [[4a3e]], [[4a3f]], [[4a3j]], [[4a3k]], [[4a3l]], [[4a3m]], [[4x67]], [[4x6a]], [[4y52]], [[4y7n]], [[5c3e]], [[5c44]], [[5c4a]], [[5c4j]], [[5c4x]], [[6bqf]], [[6bm4]], [[6bm2]], [[6blp]], [[6blo]], [[5w51]], [[5w4u]] - yRNAP II + RNA + DNA<br /> |
**[[5vvs]] - yRNAP II + RNA + DNA – Cryo EM<br /> | **[[5vvs]] - yRNAP II + RNA + DNA – Cryo EM<br /> | ||
**[[1y1w]], [[1y77]], [[2r7z]], [[2r92]], [[2r93]], [[3h3v]], [[3rzd]], [[3rzo]], [[3s15]], [[3s16]], [[3s17]], [[3s1m]], [[3s1n]], [[3s1q]], [[3s1r]], [[3s2d]], [[3s2h]] - yRNAP II + RNA | **[[1y1w]], [[1y77]], [[2r7z]], [[2r92]], [[2r93]], [[3h3v]], [[3rzd]], [[3rzo]], [[3s15]], [[3s16]], [[3s17]], [[3s1m]], [[3s1n]], [[3s1q]], [[3s1r]], [[3s2d]], [[3s2h]] - yRNAP II + RNA | ||
| Line 214: | Line 304: | ||
**[[3o2q]], [[3o2s]] – hRNAP II subunit α C-terminal + symplekin <br /> | **[[3o2q]], [[3o2s]] – hRNAP II subunit α C-terminal + symplekin <br /> | ||
**[[3j0k]], [[5iy6]], [[5iy7]], [[5iy8]], [[5iy9]], [[5iya]], [[5iyb]], [[5iyc]], [[5iyd]] – hRNAP II + TFIIF – Cryo EM <br /> | **[[3j0k]], [[5iy6]], [[5iy7]], [[5iy8]], [[5iy9]], [[5iya]], [[5iyb]], [[5iyc]], [[5iyd]] – hRNAP II + TFIIF – Cryo EM <br /> | ||
| + | **[[7dti]] – hRNAP II subunit RPB6 + TFIIH – NMR <br /> | ||
| + | **[[6xre]] – hRNAP II + p53 – Cryo EM <br /> | ||
**[[2lto]] - hRNAP II subunit RPB1 + Tudor domain containing protein 3<br /> | **[[2lto]] - hRNAP II subunit RPB1 + Tudor domain containing protein 3<br /> | ||
| + | **[[8jal]], [[8jaq]], [[8jar]], [[8jas]], [[8jau]], [[8jav]] – hRNAP II in cullin-RING E3 ubiquitin ligase – Cryo EM <br /> | ||
| + | **[[7xt7]], [[7xtd]], [[7xti]] – hRNAP II in elongation complex + nucleosome – Cryo EM <br /> | ||
| + | **[[8bvw]], [[8byq]] – hRNAP II in pre-initiation complex + nucleosome – Cryo EM<br /> | ||
| + | **[[8p4f]] – hRNAP II in co-transcriptional capping complex – Cryo EM<br /> | ||
| + | **[[7nvu]], [[7nvt]], [[7nvu]] - pRNAP II + DNA + TFIIA + TFIIF + TATA-box-binding protein – pig - Cryo EM<br /> | ||
| + | **[[7edx]], [[7eg7]], [[7eg8]], [[7eg9]], [[7ega]], [[7egb]], [[7egc]] - pRNAP II + DNA + TFIIA + TFIIB + TFIIE + TFIIF + TATA-box-binding protein - Cryo EM<br /> | ||
| + | **[[7nw0]] - pRNAP II + DNA + TFIIB + TFIIH + MAT1 + TATA-box-binding protein - Cryo EM<br /> | ||
| + | **[[8a40]] - pRNAP II in elongation complex + TFIIS - Cryo EM<br /> | ||
| + | **[[7und]] – pRNAP II + nucleosome – Cryo EM<br /> | ||
| + | **[[7okx]], [[7oky]] – pRNAP II + RNA + DNA + SPT5 + ELL2 – Cryo EM<br /> | ||
| + | **[[7ol0]] – pRNAP II + RNA + DNA + SPT5 – Cryo EM<br /> | ||
| + | **[[7oo3]] – pRNAP II + RNA + CSA + CSB + DDB1 + UVSSA – Cryo EM<br /> | ||
| + | **[[7oop]], [[7opc]], [[7opd]] – pRNAP II + RNA + CSA + CSB + DDB1 + UVSSA – Cryo EM<br /> | ||
| + | **[[7oob]] – pRNAP II + RNA + CSA + CSB + SPT6 + UVSSA + PAF – Cryo EM<br /> | ||
| + | **[[6gml]] – pRNAP II + RNA + DNA + DSIF + NELF – Cryo EM<br /> | ||
| + | **[[6gmh]], [[6ted]] – pRNAP II + RNA + DNA + DSIF + PAF + SPT6 – Cryo EM<br /> | ||
| + | **[[6exv]] – pRNAP II + RNA + DNA + amatoxin – Cryo EM<br /> | ||
| + | **[[8oew]] – pRNAP II + RNA + DNA + elongin A,B,C – Cryo EM<br /> | ||
| + | **[[8oeu]] – pRNAP II + RNA + DNA + SPT6 – Cryo EM<br /> | ||
| + | **[[8oev]], [[8of0]] – pRNAP II + RNA + DNA + elongin A,B,C + SPT6 – Cryo EM<br /> | ||
| + | **[[8p4b]], [[8p4c]] – pRNAP II in co-transcriptional capping complex – Cryo EM<br /> | ||
| + | **[[7b7u]], [[7f4g]] – pRNAP II + hRPAP2 – Cryo EM<br /> | ||
| + | **[[7nvs]], [[7nvy]], [[7nvz]] – pRNAP II in pre-initiation complex – Cryo EM<br /> | ||
| + | **[[7nvr]] – pRNAP II in pre-initiation complex + hmediator – Cryo EM<br /> | ||
| + | **[[7b0y]] – pRNAP II in transcription complex + U1 SNRNP – Cryo EM<br /> | ||
**[[1pqv]], [[1y1v]], [[4bbr]], [[4bbs]] - yRNAP II + TFIIS<br /> | **[[1pqv]], [[1y1v]], [[4bbr]], [[4bbs]] - yRNAP II + TFIIS<br /> | ||
**[[1y1y]] - yRNAP II + TFIIS + DNA +RNA <br /> | **[[1y1y]] - yRNAP II + TFIIS + DNA +RNA <br /> | ||
**[[1r5u]], [[3k7a]], [[3k1f]] - yRNAP II + TFIIB <br /> | **[[1r5u]], [[3k7a]], [[3k1f]] - yRNAP II + TFIIB <br /> | ||
| + | **[[7mk9]] - yRNAP II + DNA + TIIF – Cryo EM<br /> | ||
**[[4v1o]], [[5fyw]], [[5fz5]], [[5sva]] - yRNAP II + DNA + TIIF + TBP + mediator – Cryo EM<br /> | **[[4v1o]], [[5fyw]], [[5fz5]], [[5sva]] - yRNAP II + DNA + TIIF + TBP + mediator – Cryo EM<br /> | ||
**[[2l0i]] – yRNAP C-terminal + RTT103 – NMR<br /> | **[[2l0i]] – yRNAP C-terminal + RTT103 – NMR<br /> | ||
**[[4bxx]], [[4bxz]], [[4by1]], [[4by7]] – yRNAP II + RNA + DNA + transcription factor Bye1<br /> | **[[4bxx]], [[4bxz]], [[4by1]], [[4by7]] – yRNAP II + RNA + DNA + transcription factor Bye1<br /> | ||
**[[5vvr]] - yRNAP II + DNA + RNA + Rad26 – Cryo EM<br /> | **[[5vvr]] - yRNAP II + DNA + RNA + Rad26 – Cryo EM<br /> | ||
| - | **[[6upx]], [[6upy]], [[6upz]], [[6uq0]], [[6uq1]], [[6uq2]], [[6uq3]] - yRNAP II in elongation complex<br /> | + | **[[6upx]], [[6upy]], [[6upz]], [[6uq0]], [[6uq1]], [[6uq2]], [[6uq3]], [[7rim]], [[7rip]], [[7riq]] [[7riw]], [[7rix]], [[7riy]] - yRNAP II in elongation complex<br /> |
| - | **[[ | + | **[[6inq]], [[6a5u]], [[6a5t]], [[6a5r]], [[6a5p]], [[6a5o]], [[6a5l]], [[7nkx]], [[7nky]] – yRNAP II + DNA + RNA + nucleosome – Cryo EM<br /> |
| - | **[[ | + | **[[7ml0]], [[7ml1]], [[7ml2]], [[7ml4]], [[7o4i]], [[7o4j]], [[7o4k]], [[7o4l]], [[7o72]], [[7o73]], [[7o75]] - yRNAP II + DNA + TFIIH + TBP – Cryo EM<br /> |
| - | **[[ | + | **[[7kpv]] – yRNAP II cyclin-like subunit in Cdk8 kinase module – Cryo EM<br /> |
| + | **[[8cen]] – yRNAP II in pre-initiation complex + mediator – Cryo EM<br /> | ||
| + | **[[7zs9]], [[7zsa]], [[7zsb]] – yRNAP II in pre-initiation complex + nucleosome – Cryo EM<br /> | ||
| + | **[[8ceo]] – yRNAP II in pre-initiation complex + nucleosome + mediator – Cryo EM<br /> | ||
| + | **[[8h0v]], [[8h0w]] – KpRNAP II in chromatosome – Komagataella phaffii - Cryo EM<br /> | ||
| + | **[[7xse]], [[7xsx]], [[7xsz]] – KpRNAP II in elongation complex + nucleosome - Cryo EM<br /> | ||
| + | **[[8he5]] – KpRNAP II in elongation complex + nucleosome + Rad26 + Elf1- Cryo EM<br /> | ||
| + | **[[7wbv]], [[7wbw]], [[7wbx]] – KpRNAP II in elongation complex + Elf1 + Spt4/5 - Cryo EM<br /> | ||
| + | **[[7xn7]] – KpRNAP II in elongation complex + Elf1 + Spt4/5 + Spt6 + Spn1 + Paf1C - Cryo EM<br /> | ||
*''Eukaryotic DNA-dependent RNAP II complex with small molecule'' | *''Eukaryotic DNA-dependent RNAP II complex with small molecule'' | ||
| Line 235: | Line 361: | ||
*Eukaryotic DNA-dependent RNAP III | *Eukaryotic DNA-dependent RNAP III | ||
| - | **[[2xub]], [[2xv4]] - hRNAP III | + | **[[7a6h]], [[7ae1]], [[7ae3]], [[7aea]], [[7ast]], [[7d58]], [[7d59]], [[7dn3]], [[7du2]], [[7fji]], [[7fjj]] - hRNAP III – Cryo EM<br /> |
| - | **[[5afq]] - hRNAP III subunits | + | **[[8ity]], [[8iuh]] - hRNAP III in pre-initiation complex – Cryo EM<br /> |
| - | **[[ | + | **[[2xub]], [[2xv4]] - hRNAP III subunit Rpc3<br /> |
| + | **[[5afq]] - hRNAP III subunits Rpc3 + Rpc32B<br /> | ||
| + | **[[7asu]], [[7asv]] - hRNAP III subunit Rpc5<br /> | ||
**[[2dk5]] – hRNAP III winged helix domain (mutant) – NMR<br /> | **[[2dk5]] – hRNAP III winged helix domain (mutant) – NMR<br /> | ||
**[[2yu3]] - hRNAP III winged helix domain<br /> | **[[2yu3]] - hRNAP III winged helix domain<br /> | ||
| + | **[[2dk8]] – RNAP III RPC34 domain - mouse – NMR<br /> | ||
**[[2ckz]], [[5fj9]], [[5fja]], [[6eu3]], [[6eu2]] - yRNAP III - Cryo EM<br /> | **[[2ckz]], [[5fj9]], [[5fja]], [[6eu3]], [[6eu2]] - yRNAP III - Cryo EM<br /> | ||
| - | **[[5fj8]], [[6f41]] - yRNAP III | + | **[[5fj8]], [[6f41]], [[7z1m]], [[7z1n]], [[7z1o]], [[8bws]] - yRNAP III in elongation complex - Cryo EM<br /> |
**[[6f44]], [[6f42]], [[6f40]], [[6eu1]] - yRNAP III + DNA – Cryo EM<br /> | **[[6f44]], [[6f42]], [[6f40]], [[6eu1]] - yRNAP III + DNA – Cryo EM<br /> | ||
**[[6cnf]], [[6cnd]], [[6cnc]], [[6cnb]] - yRNAP III + DNA + TFIIIB – Cryo EM<br /> | **[[6cnf]], [[6cnd]], [[6cnc]], [[6cnb]] - yRNAP III + DNA + TFIIIB – Cryo EM<br /> | ||
| Line 248: | Line 377: | ||
**[[6eu0]] - yRNAP III + DNA + TFIIIB + TATA-box-binding protein – Cryo EM<br /> | **[[6eu0]] - yRNAP III + DNA + TFIIIB + TATA-box-binding protein – Cryo EM<br /> | ||
**[[6tut]] - yRNAP III complex + MAF1 – Cryo EM<br /> | **[[6tut]] - yRNAP III complex + MAF1 – Cryo EM<br /> | ||
| + | **[[7z0h]], [[7z2z]], [[7z30]], [[7z31]] - yRNAP III complex + Ty1 integrase – Cryo EM<br /> | ||
| + | **[[7z1l]] - yRNAP III pre-termination complex – Cryo EM<br /> | ||
**[[3ayh]] - fyRNAP III subunit Rpc8+Rpc9<br /> | **[[3ayh]] - fyRNAP III subunit Rpc8+Rpc9<br /> | ||
| Line 255: | Line 386: | ||
**[[6rwe]], [[6ruo]], [[6rui]], [[6rrd]], [[6rqt]], [[6rql]], [[6rqh]], [[6o6c]], [[6hls]] - yRNAP – Cryo EM<br /> | **[[6rwe]], [[6ruo]], [[6rui]], [[6rrd]], [[6rqt]], [[6rql]], [[6rqh]], [[6o6c]], [[6hls]] - yRNAP – Cryo EM<br /> | ||
**[[6hlr]], [[6hlq]], [[6hko]] - yRNAP + nucleotide analog – Cryo EM<br /> | **[[6hlr]], [[6hlq]], [[6hko]] - yRNAP + nucleotide analog – Cryo EM<br /> | ||
| - | **[[6j51]], [[6j50]], [[6j4z]], [[6j4y]], [[6j4x]], [[6j4w]], [[6ir9]] - yRNAP + Elf1 + Spt4 + Spt5 + | + | **[[6j51]], [[6j50]], [[6j4z]], [[6j4y]], [[6j4x]], [[6j4w]], [[6ir9]] - yRNAP + Elf1 + Spt4 + Spt5 + nucleosome – Cryo EM<br /> |
| - | **[[6i84]] - yRNAP + DNA + | + | **[[6i84]] - yRNAP + DNA + nucleosome – Cryo EM<br /> |
| - | **[[6gyl]], [[6gym]], [[6gyk]] - yRNAP + DNA + TBP + | + | **[[6gyl]], [[6gym]], [[6gyk]], [[7mei]] - yRNAP + DNA + TBP + TFIIH – Cryo EM<br /> |
| - | *Eukaryotic DNA-dependent RNAP μ or DNA-directed DNA/RNA polymerase | + | *Eukaryotic DNA-dependent RNAP IV |
| + | |||
| + | **[[7eu0]], [[7eu1]] - AtRNAP - Cryo EM<br /> | ||
| + | |||
| + | *Eukaryotic DNA-dependent RNAP V | ||
| + | |||
| + | **[[8hyj]] - AtRNAP + KTF1 - Cryo EM<br /> | ||
| + | |||
| + | *Eukaryotic DNA-dependent RNAP I+II+III+IV+V | ||
| + | |||
| + | **[[8hil]], [[8him]] - RNAP in elongation complex – cabbage - Cryo EM<br /> | ||
| + | |||
| + | *Eukaryotic DNA-dependent RNAP μ or DNA-directed DNA/RNA polymerase mu | ||
**[[4lzd]] – hRNAP μ<br /> | **[[4lzd]] – hRNAP μ<br /> | ||
| Line 267: | Line 410: | ||
**[[6ipn]], [[6ipm]], [[6ipl]], [[6ipk]], [[6ipj]], [[6ipi]], [[6iph]], [[6ak6]], [[6ak5]], [[6aeh]], [[6aec]] – hRNAP μ (mutant) + nucleotide<br /> | **[[6ipn]], [[6ipm]], [[6ipl]], [[6ipk]], [[6ipj]], [[6ipi]], [[6iph]], [[6ak6]], [[6ak5]], [[6aeh]], [[6aec]] – hRNAP μ (mutant) + nucleotide<br /> | ||
| - | *Eukaryotic DNA-dependent RNAP mitochondrial | + | *Eukaryotic DNA-dependent RNAP mitochondrial or MTRPOL |
| + | **[[7pzp]], [[7pzr]] – hRNAP – Cryo EM<br /> | ||
**[[4boc]] – hRNAP + DNA<br /> | **[[4boc]] – hRNAP + DNA<br /> | ||
**[[6erq]], [[6erp]] – hRNAP + DNA + MTTFA + dimethyladenosine transferase<br /> | **[[6erq]], [[6erp]] – hRNAP + DNA + MTTFA + dimethyladenosine transferase<br /> | ||
**[[3spa]] - hRNAP + polypeptide <br /> | **[[3spa]] - hRNAP + polypeptide <br /> | ||
| + | **[[7a8p]] - hRNAP + inhibitor <br /> | ||
| + | **[[8att]], [[8atv]], [[8atw]], [[8c5s]], [[8c5u]], [[8q63]] – yRNAP in transcription initiation complex + RNA – Cryo EM<br /> | ||
| + | **[[8ap1]] – yRNAP in transcription initiation complex + GTP – Cryo EM<br /> | ||
*''Eukaryotic DNA primase'' | *''Eukaryotic DNA primase'' | ||
| Line 286: | Line 433: | ||
**[[3lgb]], [[6di6]], [[6dhw]] - yDNAP large subunit Fe-S domain<br /> | **[[3lgb]], [[6di6]], [[6dhw]] - yDNAP large subunit Fe-S domain<br /> | ||
**[[6du0]], [[6dtz]], [[6dtv]], [[6di2]] - yDNAP large subunit Fe-S domain (mutant)<br /> | **[[6du0]], [[6dtz]], [[6dtv]], [[6di2]] - yDNAP large subunit Fe-S domain (mutant)<br /> | ||
| + | **[[7tl2]] - yDNAP large subunit C-terminal domain (mutant)<br /> | ||
*''Eukaryotic DNA primase complex'' | *''Eukaryotic DNA primase complex'' | ||
| Line 296: | Line 444: | ||
**[[4bpx]] - hDNAP small (mutant) + DNA polymerase α catalytic subunit<br /> | **[[4bpx]] - hDNAP small (mutant) + DNA polymerase α catalytic subunit<br /> | ||
**[[5exr]] - hDNAP small + large subunits + DNA polymerase α catalytic subunit<br /> | **[[5exr]] - hDNAP small + large subunits + DNA polymerase α catalytic subunit<br /> | ||
| + | **[[8d96]] - hDNAP large subunit + DNA polymerase α catalytic subunit + DNA - Cryo EM<br /> | ||
| + | **[[8d0k]] [[8d9d]] - hDNAP small + large subunits + CST + DNA polymerase α catalytic subunit + DNA – Cryo EM<br /> | ||
| + | **[[7u5c]], [[8d0b]] - hDNAP small + large subunits + CST + DNA polymerase α catalytic+B subunits + DNA – Cryo EM<br /> | ||
| + | **[[7opl]] - hDNAP small + large subunits + Nsp1 + DNA polymerase α catalytic+B subunits – Cryo EM<br /> | ||
| + | **[[7tl3]], [[7tl4]] – yDNAP large subunit C terminal (mutant)<br /> | ||
| + | **[[8foc]], [[8fod]], [[8foe]], [[8foh]], [[8foj]], [[8fok]] - yDNAP small + large subunits + DNA polymerase α catalytic+B subunits – Cryo EM<br /> | ||
| + | **[[8g99]] - fDNAP large subunit + DNA polymerase α catalytic+B subunits – frog - Cryo EM<br /> | ||
| + | **[[8ucv]] - fDNAP large subunit + DNA polymerase α catalytic subunit + DNA - Cryo EM<br /> | ||
| + | **[[8g9f]] - fDNAP small+large subunits + DNA polymerase α catalytic subunit + DNA - Cryo EM<br /> | ||
| + | **[[8g9o]] - fDNAP large subunit + DNA polymerase α catalytic+B subunits + DNA - Cryo EM<br /> | ||
| + | **[[8g9l]] - fDNAP large subunit + DNA polymerase α catalytic+B subunits + DNA + RNA - Cryo EM<br /> | ||
*''Bacterial DNA primase'' | *''Bacterial DNA primase'' | ||
| Line 306: | Line 465: | ||
**[[5w33]] - MtudnaG RPD 112-432<br /> | **[[5w33]] - MtudnaG RPD 112-432<br /> | ||
**[[5z51]] - MtudnaG helicase-binding domain 482-637<br /> | **[[5z51]] - MtudnaG helicase-binding domain 482-637<br /> | ||
| - | **[[5vaz]] – | + | **[[5vaz]] – PadnaG <br /> |
**[[4im9]] – VcdnaG C-terminal<br /> | **[[4im9]] – VcdnaG C-terminal<br /> | ||
**[[3m1m]] – DNAP RNA polymerase domain – ''Sulfolobus islandicus''<br /> | **[[3m1m]] – DNAP RNA polymerase domain – ''Sulfolobus islandicus''<br /> | ||
| Line 314: | Line 473: | ||
**[[1g71]] - PfDNAP small subunit<br /> | **[[1g71]] - PfDNAP small subunit<br /> | ||
**[[4e2k]] – SaDNAP – ''Staphylococcus aureus''<br /> | **[[4e2k]] – SaDNAP – ''Staphylococcus aureus''<br /> | ||
| + | **[[7ola]], [[7om0]] – SaDNAP – Cryo EM<br /> | ||
**[[2lzn]] – SaDNAP C terminal – NMR<br /> | **[[2lzn]] – SaDNAP C terminal – NMR<br /> | ||
**[[5guj]] – BsdnaG RNAP domain <br /> | **[[5guj]] – BsdnaG RNAP domain <br /> | ||
| Line 325: | Line 485: | ||
**[[4m4w]] - GsdnaG helicase binding domain + helicase + DnaI<br /> | **[[4m4w]] - GsdnaG helicase binding domain + helicase + DnaI<br /> | ||
**[[3b39]] – EcdnaG catalytic domain + DNA<br /> | **[[3b39]] – EcdnaG catalytic domain + DNA<br /> | ||
| + | **[[7t22]], [[7t23]] – EcdnaG C-terminal (mutant) + helicase + DNA – Cryo EM<br /> | ||
**[[5w36]], [[5w35]], [[5w34]] - MtudnaG + DNA<br /> | **[[5w36]], [[5w35]], [[5w34]] - MtudnaG + DNA<br /> | ||
**[[1v34]] - PhDNAP small subunit + UTP<br /> | **[[1v34]] - PhDNAP small subunit + UTP<br /> | ||
**[[4edg]], [[4edk]], [[4edr]], [[4edt]], [[4edv]], [[4ee1]] – SaDNAP + nucleotide<br /> | **[[4edg]], [[4edk]], [[4edr]], [[4edt]], [[4edv]], [[4ee1]] – SaDNAP + nucleotide<br /> | ||
**[[5of3]] - SsDNAP small + large subunit + protein<br /> | **[[5of3]] - SsDNAP small + large subunit + protein<br /> | ||
| + | **[[7uy8]] - DNAP small + large subunits + DNA polymerase α catalytic+B subunits – ''Tetrahymena thermophile'' - Cryo EM<br /> | ||
| + | |||
*''Phage DNA primase'' | *''Phage DNA primase'' | ||
| Line 335: | Line 498: | ||
**[[6k9c]], [[6k9e]], [[6lrb]] - NrsDNAP C terminal 305-718 <br /> | **[[6k9c]], [[6k9e]], [[6lrb]] - NrsDNAP C terminal 305-718 <br /> | ||
**[[6jon]], [[6jop]], [[6joq]], [[6k9a]] - NrsDNAP N terminal + nucleotide<br /> | **[[6jon]], [[6jop]], [[6joq]], [[6k9a]] - NrsDNAP N terminal + nucleotide<br /> | ||
| + | **[[8dwj]] – T4DNAP + RNA + DNA – Escherichia phage T4 – Cryo EM<br /> | ||
| + | **[[8dvf]], [[8dvi]], [[8dw6]] – T4DNAP + helicase + DNA – Cryo EM<br /> | ||
| + | **[[8gao]] – T4DNAP + helicase + DNA + RNA – Cryo EM<br /> | ||
*''RNA polymerase from Bacteriophage T7 or DNA primase/helicase or GP4'' | *''RNA polymerase from Bacteriophage T7 or DNA primase/helicase or GP4'' | ||
| Line 346: | Line 512: | ||
**[[1cez]], [[1h38]], [[1qln]], [[2pi4]], [[2pi5]] - T7RNAP + DNA<br /> | **[[1cez]], [[1h38]], [[1qln]], [[2pi4]], [[2pi5]] - T7RNAP + DNA<br /> | ||
**[[6n7v]], [[6n7t]], [[6n7s]], [[6n7n]], [[6n7i]] - T7RNAP (mutant) + DNA + TTP – Cryo EM<br /> | **[[6n7v]], [[6n7t]], [[6n7s]], [[6n7n]], [[6n7i]] - T7RNAP (mutant) + DNA + TTP – Cryo EM<br /> | ||
| - | **[[1msw]], [[1s0v]], [[1s76]], [[1s77]], [[3e2e]], [[3e3j]] - T7RNAP | + | **[[1msw]], [[1s0v]], [[1s76]], [[1s77]], [[3e2e]], [[3e3j]], [[8dh0]], [[8dh1]], [[8dh2]], [[8dh3]], [[8dh4]], [[8dh5]] - T7RNAP in elongation complex<br /> |
**[[6n9x]], [[6n9w]], [[6n9v]], [[6n9u]] - T7RNAP (mutant) + GP5 + DNA + RNA – Cryo EM<br /> | **[[6n9x]], [[6n9w]], [[6n9v]], [[6n9u]] - T7RNAP (mutant) + GP5 + DNA + RNA – Cryo EM<br /> | ||
**[[5ikn]] - T7RNAP (mutant) + GP5 + thioredoxin<br /> | **[[5ikn]] - T7RNAP (mutant) + GP5 + thioredoxin<br /> | ||
| - | *RNA-dependent RNAP | + | *RNA-dependent RNAP or cap-snatching endonuclease |
| + | **[[7roz]] – AtRNAP 2 – Cryo EM<br /> | ||
**[[3phu]], [[1khv]], [[1khw]] – HfRNAP L RNA-directed – Hemorrhagic fever virus<br /> | **[[3phu]], [[1khv]], [[1khw]] – HfRNAP L RNA-directed – Hemorrhagic fever virus<br /> | ||
**[[5v5i]], [[5v5h]], [[5v5g]] – HfRNAP L + ubiquitin<br /> | **[[5v5i]], [[5v5h]], [[5v5g]] – HfRNAP L + ubiquitin<br /> | ||
| Line 361: | Line 528: | ||
**[[1tql]], [[2ijd]], [[2ijf]], [[4nlo]], [[4nlp]], [[4nlq]], [[4nlr]], [[4nls]], [[4nlt]], [[4nlu]], [[4nlv]], [[4nlw]], [[4nlx]], [[4nly]], [[4r0e]] - PoRNAP (mutant) <br /> | **[[1tql]], [[2ijd]], [[2ijf]], [[4nlo]], [[4nlp]], [[4nlq]], [[4nlr]], [[4nls]], [[4nlt]], [[4nlu]], [[4nlv]], [[4nlw]], [[4nlx]], [[4nly]], [[4r0e]] - PoRNAP (mutant) <br /> | ||
**[[2xi5]], [[2xi7]] – BvRNAP L N-terminal – Bunyavirus<br /> | **[[2xi5]], [[2xi7]] – BvRNAP L N-terminal – Bunyavirus<br /> | ||
| - | **[[3jsb]] – | + | **[[7x6s]] – LcvRNAP L– Lymphocytic choriomengitis virus - Cryo EM<br /> |
| + | **[[3jsb]] – LcvRNAP L (mutant) <br /> | ||
**[[2wk4]], [[2uut]], [[2uuw]] – SvRNAP (mutant) – Sapporo virus<br /> | **[[2wk4]], [[2uut]], [[2uuw]] – SvRNAP (mutant) – Sapporo virus<br /> | ||
**[[2ckw]] - SvRNAP residues 1135-1649 <br /> | **[[2ckw]] - SvRNAP residues 1135-1649 <br /> | ||
**[[3nky]], [[4wyl]], [[4wyw]], [[6gvv]] - FmRNAP (mutant) - Foot-and-mouth virus<br /> | **[[3nky]], [[4wyl]], [[4wyw]], [[6gvv]] - FmRNAP (mutant) - Foot-and-mouth virus<br /> | ||
**[[1hhs]], [[4a8o]], [[4b02]], [[1hi8]], [[5fj6]] – P6RNAP – Bacteriophage φ-6<br /> | **[[1hhs]], [[4a8o]], [[4b02]], [[1hi8]], [[5fj6]] – P6RNAP – Bacteriophage φ-6<br /> | ||
| + | **[[7ogp]], [[7ogr]] – RNAP – Bacteriophage φ-kz – Cryo EM<br /> | ||
| + | **[[7s00]], [[7um1]] – AR9RNAP – Bacteriophage AR9 – Cryo EM<br /> | ||
| + | **[[7s01]], [[7um0]] – AR9RNAP + DNA – Cryo EM<br /> | ||
**[[2jl9]], [[2jlf]], [[1wac]] – P6RNAP (mutant) <br /> | **[[2jl9]], [[2jlf]], [[1wac]] – P6RNAP (mutant) <br /> | ||
**[[5fj7]] – P6RNAP + major inner protein P1 <br /> | **[[5fj7]] – P6RNAP + major inner protein P1 <br /> | ||
| Line 389: | Line 560: | ||
**[[3ddk]] – CvRNAP residues 1724-2185 <br /> | **[[3ddk]] – CvRNAP residues 1724-2185 <br /> | ||
**[[3nah]], [[3nai]], [[3qid]], [[3uqs]] – MnvRNAP – Murine norovirus<br /> | **[[3nah]], [[3nai]], [[3qid]], [[3uqs]] – MnvRNAP – Murine norovirus<br /> | ||
| - | **[[4wfx]], [[4wfy]], [[4wfz]] – CvRNAP | + | **[[4wfx]], [[4wfy]], [[4wfz]] – CvRNAP RdrP domain (mutant)<br /> |
| - | **[[2j7n]], [[2j7o]] – | + | **[[2j7n]], [[2j7o]] – NcRNAP residues 381-1402 – Neurospora crassa<br /> |
**[[4gzk]], [[4ieg]] – RNAP – cystovirus 12<br /> | **[[4gzk]], [[4ieg]] – RNAP – cystovirus 12<br /> | ||
**[[4i1t]] – RNAP L – Pichinde virus <br /> | **[[4i1t]] – RNAP L – Pichinde virus <br /> | ||
**[[5chs]] – VsivRNAP L N-terminal – Vescicular stomatitis Indiana virus <br /> | **[[5chs]] – VsivRNAP L N-terminal – Vescicular stomatitis Indiana virus <br /> | ||
| - | **[[4xha]], [[4xhi]] – TavRNAP – Thosea asigna virus <br /> | + | **[[4xha]], [[4xhi]], [[7om2]], [[7om9]] – TavRNAP RdRP – Thosea asigna virus <br /> |
**[[6l42]] – RNAP L – Phlebovirus – Cryo EM<br /> | **[[6l42]] – RNAP L – Phlebovirus – Cryo EM<br /> | ||
**[[6l4r]] – RNAP – Enterovirus <br /> | **[[6l4r]] – RNAP – Enterovirus <br /> | ||
| Line 400: | Line 571: | ||
**[[6ntv]] – SftvRNAP endonuclease domain 1-226<br /> | **[[6ntv]] – SftvRNAP endonuclease domain 1-226<br /> | ||
**[[6lkx]] – RNAP – Porcine respiratory virus <br /> | **[[6lkx]] – RNAP – Porcine respiratory virus <br /> | ||
| - | **[[6kld]] – | + | **[[6kld]], [[7vh2]], [[7vh3]] – MavRNAP L – Machupo virus – Cryo EM<br /> |
| - | **[[6klc]] – LvRNAP L – Lassa virus – Cryo EM<br /> | + | **[[6klc]], [[7och]], [[7oe3]], [[7oe7]] – LvRNAP L – Lassa virus – Cryo EM<br /> |
| - | **[[4miw]], [[5izh]], [[5j1n]], [[5j1p]] – | + | **[[4miw]], [[5izh]], [[5j1n]], [[5j1p]] – LvRNAP L N terminal <br /> |
| - | **[[4mtp]] – | + | **[[4mtp]], [[7d6n]] – EnvRNAP RdrP module – Encephalitis virus <br /> |
**[[4cgx]], [[4chc]] – TvRNAP N terminal – Thogoto virus <br /> | **[[4cgx]], [[4chc]] – TvRNAP N terminal – Thogoto virus <br /> | ||
**[[4chd]] – TvRNAP 627 domain <br /> | **[[4chd]] – TvRNAP 627 domain <br /> | ||
**[[4che]], [[4chf]] – TvRNAP cap-binding domain <br /> | **[[4che]], [[4chf]] – TvRNAP cap-binding domain <br /> | ||
| - | **[[5fsw]] - | + | **[[5fsw]] - RNAP C terminal – ''Thielavia terrestris''<br /> |
**[[6q99]] – RNAP – Andes virus<br /> | **[[6q99]] – RNAP – Andes virus<br /> | ||
| - | **[[5ize]] – | + | **[[5ize]] – HavRNAP L – Hantaan virus<br /> |
| + | **[[8c4s]] – HavRNAP L – Cryo EM<br /> | ||
**[[5ltf]] – LcmvRNAP L – Lymphocytic choriomeningitis mammarenavirus<br /> | **[[5ltf]] – LcmvRNAP L – Lymphocytic choriomeningitis mammarenavirus<br /> | ||
**[[5lts]] - LcmvRNAP (mutant)<br /> | **[[5lts]] - LcmvRNAP (mutant)<br /> | ||
| Line 418: | Line 590: | ||
**[[6dx2]] - RNAP OTU domain – Dera Ghazi khan virus<br /> | **[[6dx2]] - RNAP OTU domain – Dera Ghazi khan virus<br /> | ||
**[[6dx1]], [[6dwx]] - RNAP OTU domain – Qulybus virus<br /> | **[[6dx1]], [[6dwx]] - RNAP OTU domain – Qulybus virus<br /> | ||
| + | **[[7eei]] – RNAP (mutant) – Rift valley fever virus – Cryo EM<br /> | ||
*''RNA-dependent RNAP complex with RNA'' | *''RNA-dependent RNAP complex with RNA'' | ||
| Line 424: | Line 597: | ||
**[[3ol6]], [[2jlg]], [[4k4s]], [[4k4t]], [[4k4u]], [[4k4v]], [[4k4w]] – PoRNAP (mutant) + RNA <br /> | **[[3ol6]], [[2jlg]], [[4k4s]], [[4k4t]], [[4k4u]], [[4k4v]], [[4k4w]] – PoRNAP (mutant) + RNA <br /> | ||
**[[3ol7]], [[3ol8]], [[3ol9]], [[3ola]], [[3olb]] - PoRNAP (mutant) + RNA + nucleotide<br /> | **[[3ol7]], [[3ol8]], [[3ol9]], [[3ola]], [[3olb]] - PoRNAP (mutant) + RNA + nucleotide<br /> | ||
| + | **[[1wne]] – FmRNAP + RNA <br /> | ||
**[[3klv]], [[3kmq]], [[3kms]], [[3kna]], [[3nl0]], [[3nma]], [[4iqx]], [[4wzm]], [[4wzq]], [[4x2b]], [[5jxs]] – FmRNAP (mutant) + RNA<br /> | **[[3klv]], [[3kmq]], [[3kms]], [[3kna]], [[3nl0]], [[3nma]], [[4iqx]], [[4wzm]], [[4wzq]], [[4x2b]], [[5jxs]] – FmRNAP (mutant) + RNA<br /> | ||
**[[3koa]] - FmRNAP (mutant) + RNA + nucleotide<br /> | **[[3koa]] - FmRNAP (mutant) + RNA + nucleotide<br /> | ||
| - | **[[1wne]] – FmRNAP + RNA <br /> | ||
**[[2e9r]], [[2e9t]], [[2e9z]], [[2ec0]] - FmRNAP + RNA + inhibitor<br /> | **[[2e9r]], [[2e9t]], [[2e9z]], [[2ec0]] - FmRNAP + RNA + inhibitor<br /> | ||
| - | **[[1uvi]], [[1uvl]], [[1uvm]], [[1uvn]], [[4a8f]], [[4a8k]], [[4a8m]], [[4a8q]], [[4a8s]], [[4a8w]], [[4a8y – P6RNAP + RNA<br /> | + | **[[1uvi]], [[1uvl]], [[1uvm]], [[1uvn]], [[4a8f]], [[4a8k]], [[4a8m]], [[4a8q]], [[4a8s]], [[4a8w]], [[4a8y]] – P6RNAP + RNA<br /> |
| - | **[[3bsn, [[3bso]], [[3h5x]], [[3h5y]] - NvRNAP + RNA + nucleotide<br /> | + | **[[3bsn]], [[3bso]], [[3h5x]], [[3h5y]] - NvRNAP + RNA + nucleotide<br /> |
**[[2r7r]], [[2r7s]], [[2r7t]], [[2r7u]], [[2r7v]], [[2r7w]], [[2r7x]] – SrRNAP + RNA<br /> | **[[2r7r]], [[2r7s]], [[2r7t]], [[2r7u]], [[2r7v]], [[2r7w]], [[2r7x]] – SrRNAP + RNA<br /> | ||
**[[5amq]], [[5amr]] – BvRNAP + RNA<br /> | **[[5amq]], [[5amr]] – BvRNAP + RNA<br /> | ||
| + | **[[7ork]], [[7orl]], [[7orj]], [[7orm]] – BvRNAP + RNA – Cryo EM<br /> | ||
**[[4k50]] – RNAP + RNA – Human rhinovirus<br /> | **[[4k50]] – RNAP + RNA – Human rhinovirus<br /> | ||
**[[3c2p]], [[3c3l]], [[3c46]], [[3q0a]] - N4RNAP polymerase domain + promoter DNA<br /> | **[[3c2p]], [[3c3l]], [[3c46]], [[3q0a]] - N4RNAP polymerase domain + promoter DNA<br /> | ||
| Line 442: | Line 616: | ||
**[[6kle]], [[6klh]] – MvRNAP L + RNA – Cryo EM<br /> | **[[6kle]], [[6klh]] – MvRNAP L + RNA – Cryo EM<br /> | ||
**[[6z6g]], [[6z8k]] – RNAP L + RNA – La crosse orthobunyavirus - Cryo EM<br /> | **[[6z6g]], [[6z8k]] – RNAP L + RNA – La crosse orthobunyavirus - Cryo EM<br /> | ||
| + | **[[8ci5]] – RNAP L + RNA – sin nombre orthohantavirus - Cryo EM<br /> | ||
| + | **[[7y7q]] – NcRNAP + RNA + GTP<br /> | ||
| + | **[[7y7p]] – NcRNAP + RNA + AMPNPP<br /> | ||
| + | **[[7y7r]] – NcRNAP + RNA + DNA + GTP<br /> | ||
| + | **[[7ela]], [[7oea]], [[7oeb]], [[7ojj]], [[7ojk]], [[7ojl]], [[7ojn]] – LvRNAP + RNA – Cryo EM<br /> | ||
| + | **[[8c4t]], [[8c4u]], [[8c4v]] – HavRNAP L + RNA – Cryo EM<br /> | ||
| + | **[[8as6]], [[8as7]], [[8asb]], [[8asd]], [[8asg]] – RNAP L + RNA – SFTS virus - Cryo EM<br /> | ||
| + | **[[7om7]], [[7oma]] – TavRNAP RdrP domain + RNA<br /> | ||
*''RNA-dependent RNAP complex with protein'' | *''RNA-dependent RNAP complex with protein'' | ||
| Line 448: | Line 630: | ||
**[[3phx]], [[3pse]] – HfRNAP + ISG15<br /> | **[[3phx]], [[3pse]] – HfRNAP + ISG15<br /> | ||
**[[6u5o]] – HmpvRNAP L + phosphoprotein – Cryo EM<br /> | **[[6u5o]] – HmpvRNAP L + phosphoprotein – Cryo EM<br /> | ||
| - | **[[6pzk]], [[6uen]] – RNAP L + phosphoprotein – Human respiratory syncytial virus - Cryo EM<br /> | + | **[[8fpj]] – HmpvRNAP L + MRK-1 – Cryo EM<br /> |
| + | **[[6pzk]], [[6uen]], [[8fpi]], [[8fu3]] – RNAP L + phosphoprotein – Human respiratory syncytial virus - Cryo EM<br /> | ||
**[[6v85]], [[6v86]] – RNAP L + phosphoprotein – Parainfluenza virus <br /> | **[[6v85]], [[6v86]] – RNAP L + phosphoprotein – Parainfluenza virus <br /> | ||
**[[6po2]], [[6pns]] – RNAP + VP3 – Bluetongue virus - Cryo EM<br /> | **[[6po2]], [[6pns]] – RNAP + VP3 – Bluetongue virus - Cryo EM<br /> | ||
| - | **[[2d7s]], [[2f8e]] – FmRNAP + VPG <br /> | + | **[[2d7s]], [[2f8e]], [[8c1n]] – FmRNAP + VPG <br /> |
| + | **[[8c2p]] – FmRNAP + protein 3B-3 <br /> | ||
**[[5y3d]] – MnvRNAP + VPG <br /> | **[[5y3d]] – MnvRNAP + VPG <br /> | ||
**[[3cdw]] - CvRNAP + POP + VPG<br /> | **[[3cdw]] - CvRNAP + POP + VPG<br /> | ||
| Line 465: | Line 649: | ||
**[[6k32]] – RvARNAP + Vp1 + Vp4 + RNA – Cypovirus 1 - Cryo EM<br /> | **[[6k32]] – RvARNAP + Vp1 + Vp4 + RNA – Cypovirus 1 - Cryo EM<br /> | ||
**[[6oar]], [[6oat]] – RNAP OUT domain + ISG17 – Kupe virus <br /> | **[[6oar]], [[6oat]] – RNAP OUT domain + ISG17 – Kupe virus <br /> | ||
| - | **[[6xqb]], [[7bzf]], [[7c2k]] – | + | **[[7yer]], [[7yes]], [[8jsl]], [[8jsm]], [[8jsn]] – EbvRNAP + Vp35 – Ebola virus – Cryo EM<br /> |
| + | **[[7yet]] – EbvRNAP + Vp35+ drug – Cryo EM<br /> | ||
| + | **[[7ckl]], [[7ckm]], [[7elb]], [[7vgq]], [[7vh1]] – MavRNAP L + matrix protein Z – Cryo EM<br /> | ||
| + | **[[7el9]], [[7elc]] – MavRNAP L + matrix protein Z + RNA – Cryo EM<br /> | ||
| + | **[[7x6v]] – LcvRNAP L + matrix protein Z – Cryo EM<br /> | ||
| + | **[[7eju]] – RNAP L + matrix protein Z – Junin virus - Cryo EM<br /> | ||
| + | **[[7yot]], [[7yov]], [[7you]] – RNAP + P protein – Newcastle disease virus – Cryo EM<br /> | ||
| + | |||
| + | *''RNA-dependent RNAP from SARS-COV2” | ||
| + | |||
| + | **[[7btf]], [[7bw4]] – SCRNAP + non-structural proteins – SARS-COV-2 - Cryo EM<br /> | ||
| + | **[[6xqb]], [[7bzf]], [[7c2k]], [[7uo7]], [[7uo9]], [[7uob]], [[7uoe]], [[8gwb]], [[8gwe]] – SCRNAP + non-structural proteins + RNA - Cryo EM<br /> | ||
| + | **[[7aap]], [[7b38]], [[7b3c]], [[7ctt]], [[7d4f]], [[7dfg]], [[7dfh]], [[7doi]], [[7dok]], [[7l1f]], [[7p35]], [[7uo4]] – SCRNAP + non-structural proteins + RNA + drug - Cryo EM<br /> | ||
| + | **[[7ed5]], [[8gwn]], [[8gwo]] – SCRNAP + non-structural proteins + RNA + inhibitor - Cryo EM<br /> | ||
| + | **[[7krn]], [[7rdx]], [[7rdy]], [[7rdz]], [[7re0]], [[7re1]], [[7re2]], [[7re3]] – SCRNAP + non-structural proteins + RNA + helicase - Cryo EM<br /> | ||
| + | **[[7cxm]], [[7cxn]], [[7cyq]] – SCRNAP 4393-5324 (mutant)+ non-structural proteins + RNA + helicase - Cryo EM<br /> | ||
| + | **[[7oyg]] – SCRNAP + non-structural proteins + RNA + PP1AB - Cryo EM<br /> | ||
| + | **[[8gy6]] – SCRNAP + non-structural proteins + RNA + toxin - Cryo EM<br /> | ||
| + | **[[8gwf]], [[8gwg]] – SCRNAP + non-structural proteins + RNA + helicase + inhibitor - Cryo EM<br /> | ||
| + | **[[7eiz]] – SCRNAP + non-structural proteins + RNA + methyltransferase + exoribonuclease - Cryo EM<br /> | ||
*''RNA-dependent RNAP complex with small molecule'' | *''RNA-dependent RNAP complex with small molecule'' | ||
| - | **[[2xwy]], [[3mf5]], [[3hkw]], [[3hky]], [[3lkh]], [[3gnv]], [[3gnw]], [[3h98]], [[3g86]], [[3h59]], [[1nhu]], [[1nhv]], [[2brk]], [[2brl]], [[2gc8]], [[2giq]], 2gir]], [[2hai]], [[2hwh]], [[2hwi]], [[2i1r]], [[2ijn]], [[2jc0]], [[2jc1]], [[2qe2]], [[2qe5]], [[2wcx]], [[2who]], [[3ciz]], [[3cj0]], [[3cj2]], [[3cj3]], [[3cj4]], [[3cj5]], [[3cso]], [[3cvk]], [[3fqk]], [[3fql]], [[3gol]], [[3h5s]], [[3h5u]], [[3q0z]], [[3qgd]], [[3qge]], [[3qgf]], [[3qgg]], [[3qgh]], [[3qgi]], [[3ska]], [[3ske]], [[3skh]], 3uph]], [[3upi]], [[4dru]], [[3vqs]], [[3udl]], [[4eo6]], [[4eo8]], [[4eaw]], [[4gmc]], [[4ih5]], [[4ih6]], [[4ih7]], [[4iz0]], [[4jtz]], [[4jtw]], [[4jty]], [[4ju1]], [[4ju2]], [[4jjs]], [[4jju]], [[4j02]], [[4j04]], [[4j06]], [[4j08]], [[2yoj]], [[3tuq]], [[3tuv]], [[3u4o]], [[3u4r]], [[4mk7]], [[4mk8]], [[4mk9]], [[4mka]], [[4mkb]], [[4mz4]], [[4nld]], [[3tyq]], [[3tyv]], [[4mia]], [[4mib]], [[4oow]], [[4tlr]], [[5pzk]], [[5pzl]], [[5pzm]], | + | **[[2xwy]], [[3mf5]], [[3hkw]], [[3hky]], [[3lkh]], [[3gnv]], [[3gnw]], [[3h98]], [[3g86]], [[3h59]], [[1nhu]], [[1nhv]], [[2brk]], [[2brl]], [[2gc8]], [[2giq]], [[2gir]], [[2hai]], [[2hwh]], [[2hwi]], [[2i1r]], [[2ijn]], [[2jc0]], [[2jc1]], [[2qe2]], [[2qe5]], [[2wcx]], [[2who]], [[3ciz]], [[3cj0]], [[3cj2]], [[3cj3]], [[3cj4]], [[3cj5]], [[3cso]], [[3cvk]], [[3fqk]], [[3fql]], [[3gol]], [[3h5s]], [[3h5u]], [[3q0z]], [[3qgd]], [[3qge]], [[3qgf]], [[3qgg]], [[3qgh]], [[3qgi]], [[3ska]], [[3ske]], [[3skh]], [[3uph]], [[3upi]], [[4dru]], [[3vqs]], [[3udl]], [[4eo6]], [[4eo8]], [[4eaw]], [[4gmc]], [[4ih5]], [[4ih6]], [[4ih7]], [[4iz0]], [[4jtz]], [[4jtw]], [[4jty]], [[4ju1]], [[4ju2]], [[4jjs]], [[4jju]], [[4j02]], [[4j04]], [[4j06]], [[4j08]], [[2yoj]], [[3tuq]], [[3tuv]], [[3u4o]], [[3u4r]], [[4mk7]], [[4mk8]], [[4mk9]], [[4mka]], [[4mkb]], [[4mz4]], [[4nld]], [[3tyq]], [[3tyv]], [[4mia]], [[4mib]], [[4oow]], [[4tlr]], [[5pzk]], [[5pzl]], [[5pzm]], [[5pzn]], [[5pzo]], [[5pzp]], [[5trh]], [[5tri]], [[5trj]] - HvRNAP Ns5b domain + inhibitor<br /> |
**[[3gyn]], [[1os5]], [[3br9]], [[3bsa]], [[3bsc]], [[3cde]], [[3co9]], [[3cwj]], [[3d28]], [[3d5m]], [[3e51]], [[3frz]], [[3igv]], [[3hvo]], [[3h2l]], [[4kai]], [[4kb7]], [[4kbi]], [[4ke5]], [[4khm]], [[4khr]], [[5twm]], [[5twn]] - HvRNAP Ns5b domain (mutant) + inhibitor<br /> | **[[3gyn]], [[1os5]], [[3br9]], [[3bsa]], [[3bsc]], [[3cde]], [[3co9]], [[3cwj]], [[3d28]], [[3d5m]], [[3e51]], [[3frz]], [[3igv]], [[3hvo]], [[3h2l]], [[4kai]], [[4kb7]], [[4kbi]], [[4ke5]], [[4khm]], [[4khr]], [[5twm]], [[5twn]] - HvRNAP Ns5b domain (mutant) + inhibitor<br /> | ||
**[[2xi3]] - HvRNAP Ns5b domain (mutant) + GTP<br /> | **[[2xi3]] - HvRNAP Ns5b domain (mutant) + GTP<br /> | ||
| Line 490: | Line 693: | ||
**[[6mvo]] – RNAP (mutant) + inhibitor – Hepacivirus C<br /> | **[[6mvo]] – RNAP (mutant) + inhibitor – Hepacivirus C<br /> | ||
**[[6xya]] – SftvRNAP cap-binding domain 1695-1810 + GTP <br /> | **[[6xya]] – SftvRNAP cap-binding domain 1695-1810 + GTP <br /> | ||
| + | **[[8gwi]] – SCRNAP + inhibitor - Cryo EM<br /> | ||
| + | *Influenza virus polymerase acidic protein (or PA or subunit P2) N terminal 1-256; C-terminal 257-716 | ||
| - | + | **[[2w69]], [[3ebj]], [[4p9a]], [[4nfz]], [[4avq]], [[4e5e]], [[4zqq]], [[5jht]], [[5jhv]], [[5des]], [[7xgc]] - IvRNAP PA N terminal – Influenza virus<br /> | |
| - | + | ||
| - | **[[4p9a]], [[4nfz]], [[4avq]], [[4e5e]], [[4zqq]], [[5jht]], [[5jhv]], [[5des]] - IvRNAP PA N terminal – Influenza virus<br /> | + | |
**[[5d2o]], [[5czn]], [[3hw6]], [[6fsb]] - IvRNAP PA N terminal (mutant) <br /> | **[[5d2o]], [[5czn]], [[3hw6]], [[6fsb]] - IvRNAP PA N terminal (mutant) <br /> | ||
| - | + | **[[3hw3]], [[3hw4]], [[3hw5]] - IvRNAP PA residues N-terminal (mutant) + Mn + nucleotide <br /> | |
| - | + | **[[4w9s]], [[5fdd]], [[5fdg]], [[5i13]], [[5ieq]], [[5if2]], [[5if5]], [[5if7]], [[5if8]], [[5ifb]], [[5ifc]], [[5ifd]], [[5wa6]], [[5wa7]], [[5wb3]], [[5wap]], [[5w9g]], [[5w92]], [[5w44]], [[5v0u]], [[6nem]], [[6nel]], [[6e6x]], [[6e6w]], [[6e6v]], [[6dcz]], [[6dcy]], [[5ega]], [[5cl0]], [[5cgv]], [[5ccy]], [[4mk5]], [[4mk2]], [[4mk1]], [[4awm]], [[4awk]], [[4awh]], [[4awg]], [[4awf]], [[4e5f]], [[4e5g]], [[4e5h]], [[4e5i]], [[4e5j]], [[4e5l]], [[4yyl]], [[4zhz]], [[4zi0]], [[6fs7]], [[6fs6]], [[6fs8]], [[4avl]], [[4avg]], [[6yem]], [[7mty]], [[7mx0]], [[7n55]], [[7n68]], [[7v04]], [[8ctf]] – IvRNAP PA N terminal + inhibitor<br /> | |
| - | **[[3hw3]], [[3hw4]], [[3hw5]] - IvRNAP PA residues | + | **[[5wg9]], [[5wfz]], [[5wfw]], [[5wfm]], [[5wf3]], [[5wei]], [[5wef]], [[5web]], [[5we9]], [[5we7]], [[5wdw]], [[5wdn]], [[5wdc]], [[5wct]], [[5wcs]], [[5w73]], [[5w7u]], [[5w3i]], [[5vrj]], [[5vqn]], [[5vpx]], [[5vpt]], [[5vp8]], [[6e4c]], [[6e3p]], [[6e3o]], [[6e3n]], [[6e3m]], [[6e0q]], [[6dzq]], [[5deb]], [[5dbs]], [[5d9j]], [[5d8u]], [[5d4g]], [[5d42]], [[6fs9]], [[7ml8]], [[7rkp]] – IvRNAP PA N terminal (mutant) + inhibitor<br /> |
| - | **[[4w9s]], [[5fdd]], [[5fdg]], [[5i13]], [[5ieq]], [[5if2]], [[5if5]], [[5if7]], [[5if8]], [[5ifb]], [[5ifc]], [[5ifd]], [[5wa6]], [[5wa7]], [[5wb3]], [[5wap]], [[5w9g]], [[5w92]], [[5w44]], [[5v0u]], [[6nem]], [[6nel]], [[6e6x]], [[6e6w]], [[6e6v]], [[6dcz]], [[6dcy]], [[5ega]], [[5cl0]], [[5cgv]], [[5ccy]], [[4mk5]], [[4mk2]], [[4mk1]], [[4awm]], [[4awk]], [[4awh]], [[4awg]], [[4awf]], [[4e5f]], [[4e5g]], [[4e5h]], [[4e5i]], [[4e5j]], [[4e5l]], [[4yyl]], [[4zhz]], [[4zi0]], [[6fs7]], [[6fs6]], [[6fs8]], [[4avl]], [[4avg]], [[6yem]] – IvRNAP PA N terminal + inhibitor<br /> | + | **[[4iuj]] - IvRNAP PA C-terminal<br /> |
| - | **[[5wg9]], [[5wfz]], [[5wfw]], [[5wfm]], [[5wf3]], [[5wei]], [[5wef]], [[5web]], [[5we9]], [[5we7]], [[5wdw]], [[5wdn]], [[5wdc]], [[5wct]], [[5wcs]], [[5w73]], [[5w7u]], [[5w3i]], [[5vrj]], [[5vqn]], [[5vpx]], [[5vpt]], [[5vp8]], [[6e4c]], [[6e3p]], [[6e3o]], [[6e3n]], [[6e3m]], [[6e0q]], [[6dzq]], [[5deb]], [[5dbs]], [[5d9j]], [[5d8u]], [[5d4g]], [[5d42]], [[6fs9]] – IvRNAP PA N terminal (mutant) + inhibitor<br /> | + | **[[7zpy]] – IvRNAP PA C terminal + inhibitor<br /> |
| Line 507: | Line 710: | ||
**[[4enf]], [[4u6o]], [[4j2r]], [[2vqz]], [[5ef9]], [[5eg9]] – IvRNAP PB2 cap-binding domain<br /> | **[[4enf]], [[4u6o]], [[4j2r]], [[2vqz]], [[5ef9]], [[5eg9]] – IvRNAP PB2 cap-binding domain<br /> | ||
**[[3wi0]] – IvRNAP PB2 cap-binding domain (mutant)<br /> | **[[3wi0]] – IvRNAP PB2 cap-binding domain (mutant)<br /> | ||
| + | **[[7as2]], [[7as3]] – IvRNAP PB2 cap-binding domain (mutant) + VX<br /> | ||
| + | **[[7nft]] – IvRNAP PB2 cap-binding domain + nanobody<br /> | ||
**[[3cw4]] - IvRNAP PB2 627 + NLS domains <br /> | **[[3cw4]] - IvRNAP PB2 627 + NLS domains <br /> | ||
**[[2gmo]] - IvRNAP PB2 627 + NLS domains - NMR<br /> | **[[2gmo]] - IvRNAP PB2 627 + NLS domains - NMR<br /> | ||
**[[4eqk]], [[5efa]], [[5efc]] – IvRNAP PB2 cap-binding domain + GTP<br /> | **[[4eqk]], [[5efa]], [[5efc]] – IvRNAP PB2 cap-binding domain + GTP<br /> | ||
**[[4nce]], [[3wi1]] – IvRNAP PB2 cap-binding domain (mutant) + GTP derivative<br /> | **[[4nce]], [[3wi1]] – IvRNAP PB2 cap-binding domain (mutant) + GTP derivative<br /> | ||
| - | + | **[[4p1u]], [[4yd0]], [[5buh]], [[5jun]], [[5jur]], [[7as0]], [[7xme]] - IvRNAP PB2 cap-binding domain + inhibitor<br /> | |
| - | **[[4p1u]], [[4yd0]], [[5buh]], [[5jun]], [[5jur]] - IvRNAP PB2 cap-binding domain + inhibitor<br /> | + | **[[4ncm]], [[7as1]] – IvRNAP PB2 cap-binding domain (mutant) + inhibitor<br /> |
**[[6euy]], [[6eux]], [[6euv]] - IvRNAP PB2 cap-binding + midlink domains + inhibitor<br /> | **[[6euy]], [[6eux]], [[6euv]] - IvRNAP PB2 cap-binding + midlink domains + inhibitor<br /> | ||
**[[5wl0]] - IvRNAP PB2 cap-binding + midlink + 627 + NLS domains + inhibitor<br /> | **[[5wl0]] - IvRNAP PB2 cap-binding + midlink + 627 + NLS domains + inhibitor<br /> | ||
| Line 534: | Line 739: | ||
**[[2ztt]], [[3a1g]] - IvRNAP PB1 C terminal + RNAP PB2 N terminal<br /> | **[[2ztt]], [[3a1g]] - IvRNAP PB1 C terminal + RNAP PB2 N terminal<br /> | ||
**[[3j9b]] - IvRNAP PB1+PB2 N terminal + RNA<br /> | **[[3j9b]] - IvRNAP PB1+PB2 N terminal + RNA<br /> | ||
| + | |||
| + | *Influenza virus RNAP PB1+P2+P3 | ||
| + | |||
| + | **[[7zpm]] - IvRNAP PB1+P2+P3 – Cryo EM<br /> | ||
| + | **[[7nha]], [[7nhc]], [[7nhx]], [[7zpl]], [[8h69]] - IvRNAP PB1+P2+P3 + RNA – Cryo EM<br /> | ||
| + | **[[7ni0]], [[7nik]], [[7nil]], [[7nir]], [[7nis]], [[7nj3]], [[7nj4]], [[7nj5]], [[7nj7]], [[7nk1]], [[7nk2]], [[7nk4]], [[7nk6]], [[7nk8]], [[7nka]], [[7nkc]], [[7nki]], [[7nkr]] - IvRNAP PB1+P2+P3 + RNA + nanobody – Cryo EM<br /> | ||
| + | **[[7qtl]], [[7r0e]], [[7r1f]], [[8bdr]], [[8be0]], [[8bek]], [[8bf5]] - IvRNAP PB1+P2+P3 + RNA + mRNA – Cryo EM<br /> | ||
| + | **[[7z42]] - IvRNAP PB1+P2+P3 + RNA + RPB1 peptide – Cryo EM<br /> | ||
*Influenza virus RNAP PA+PB1+PB2 (subunits P1+p2+p3) | *Influenza virus RNAP PA+PB1+PB2 (subunits P1+p2+p3) | ||
Current revision
Updated on 16-November-2023 - For a general description of the protein see RNA polymerase
