Severin
From Proteopedia
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| - | [[ | + | <StructureSection load='1svy' size='350' side='right' scene='41/410299/Cv/6' caption='Severin domain 2 complex with Ca+2 (green) and Na+ (purple) ions [[1svy]]' pspeed='8'> |
| - | {{STRUCTURE_3fg6| PDB=3fg6 | SCENE=Severin/Cv/4 |CAPTION=Severin, [[3fg6]] }} | ||
| - | [[Severin]] is a calcium-activated protein which binds actin | + | [[Severin]] is a calcium-activated protein which binds actin. It nucleates actin assembly, severes F-actin and caps actin filaments. Severin is a member of the calcium-regulated gelsolin superfamily of actin severing and capping proteins<ref>PMID:15060630</ref>. It is named Adseverin and Scinderin as well. |
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| + | *<scene name='41/410299/Cv/9'>Ca coordination site</scene>. Water molecules are shown as red spheres. | ||
| + | *<scene name='41/410299/Cv/10'>Na coordination site</scene>. | ||
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| + | </StructureSection> | ||
== 3D Structures of Severin == | == 3D Structures of Severin == | ||
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| + | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
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[[3fg6]] – Adseverin C-terminal – human<br /> | [[3fg6]] – Adseverin C-terminal – human<br /> | ||
| - | [[1svy]] – | + | [[1svy]] – DdSeverin domain 2 – ''Dictyostelium discoideum'' <br /> |
| - | [[1svq]] - | + | [[1svq]], [[1svr]] - DdSeverin domain 2 - NMR<br /> |
| + | == References == | ||
| + | <references/> | ||
| + | [[Category:Topic Page]] | ||
Current revision
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3D Structures of Severin
Updated on 19-November-2023
3fg6 – Adseverin C-terminal – human
1svy – DdSeverin domain 2 – Dictyostelium discoideum
1svq, 1svr - DdSeverin domain 2 - NMR
References
- ↑ Summerscales J, Dawson JF. Probing Dictyostelium severin structure and function by cross linking to actin. Biochem Cell Biol. 2004 Apr;82(2):343-50. PMID:15060630 doi:http://dx.doi.org/10.1139/o04-002
