Sodium-hydrogen exchange regulatory factor

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<StructureSection load='4q3h' size='340' side='right' caption='Human NHERF-1 second PDZ domain with CXCR2 peptide chimera (PDB cod [[4q3h]])' scene=''>
<StructureSection load='4q3h' size='340' side='right' caption='Human NHERF-1 second PDZ domain with CXCR2 peptide chimera (PDB cod [[4q3h]])' scene=''>
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== Function ==
== Function ==
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NHERF interacts with ion transporters and receptors via its PDZ domains and with the merlin, ezrin, radixin and moesin proteins via its c-terminal. The CXCR2 peptide binds the second PDZ domain hydrophobic cleft<ref>PMID:26010555</ref>.
NHERF interacts with ion transporters and receptors via its PDZ domains and with the merlin, ezrin, radixin and moesin proteins via its c-terminal. The CXCR2 peptide binds the second PDZ domain hydrophobic cleft<ref>PMID:26010555</ref>.
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</StructureSection>
 
== 3D Structures of sodium-hydrogen exchange regulatory factor ==
== 3D Structures of sodium-hydrogen exchange regulatory factor ==
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[[Sodium-hydrogen exchange regulatory factor 3D structures]]
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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== References ==
== References ==
<references/>
<references/>
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</StructureSection>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 08:29, 21 November 2023

Human NHERF-1 second PDZ domain with CXCR2 peptide chimera (PDB cod 4q3h)

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Michal Harel, Joel L. Sussman

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