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5x73
From Proteopedia
(Difference between revisions)
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==The crystal Structure PDE delta in complex with R-p9== | ==The crystal Structure PDE delta in complex with R-p9== | ||
| - | <StructureSection load='5x73' size='340' side='right' caption='[[5x73]], [[Resolution|resolution]] 2.50Å' scene=''> | + | <StructureSection load='5x73' size='340' side='right'caption='[[5x73]], [[Resolution|resolution]] 2.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5x73]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5x73]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5X73 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5X73 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P59:(2R)-2-(2-fluorophenyl)-3-phenyl-1,2-dihydroquinazolin-4-one'>P59</scene></td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5x73 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5x73 OCA], [https://pdbe.org/5x73 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5x73 RCSB], [https://www.ebi.ac.uk/pdbsum/5x73 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5x73 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/PDE6D_HUMAN PDE6D_HUMAN] Acts as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude and does so by decreasing the nucleotide dissociation rate. Stabilizes Arl3-GTP by decreasing the nucleotide dissociation (By similarity). |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 24: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Chen | + | [[Category: Large Structures]] |
| - | [[Category: Jiang | + | [[Category: Chen L]] |
| - | [[Category: Sheng | + | [[Category: Jiang Y]] |
| - | [[Category: Wang | + | [[Category: Sheng C]] |
| - | [[Category: Wang | + | [[Category: Wang F]] |
| - | [[Category: Zhuang | + | [[Category: Wang R]] |
| - | + | [[Category: Zhuang C]] | |
Current revision
The crystal Structure PDE delta in complex with R-p9
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Categories: Homo sapiens | Large Structures | Chen L | Jiang Y | Sheng C | Wang F | Wang R | Zhuang C
