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5xtw

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==Crystal structure of the CysR-CTLD2 fragment of human MR at acidic pH==
==Crystal structure of the CysR-CTLD2 fragment of human MR at acidic pH==
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<StructureSection load='5xtw' size='340' side='right' caption='[[5xtw]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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<StructureSection load='5xtw' size='340' side='right'caption='[[5xtw]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5xtw]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XTW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5XTW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5xtw]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5XTW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5XTW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5xtw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xtw OCA], [http://pdbe.org/5xtw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5xtw RCSB], [http://www.ebi.ac.uk/pdbsum/5xtw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5xtw ProSAT]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=MES:2-(N-MORPHOLINO)-ETHANESULFONIC+ACID'>MES</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5xtw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5xtw OCA], [https://pdbe.org/5xtw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5xtw RCSB], [https://www.ebi.ac.uk/pdbsum/5xtw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5xtw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MRC1_HUMAN MRC1_HUMAN]] Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.
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[https://www.uniprot.org/uniprot/MRC1_HUMAN MRC1_HUMAN] Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains. Acts as phagocytic receptor for bacteria, fungi and other pathogens.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: He, Y]]
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[[Category: Homo sapiens]]
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[[Category: Hu, Z]]
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[[Category: Large Structures]]
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[[Category: Collagen binding]]
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[[Category: He Y]]
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[[Category: Endocytic receptor]]
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[[Category: Hu Z]]
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[[Category: Immune receptor]]
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[[Category: Lectin-activity]]
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[[Category: Sugar binding protein]]
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Current revision

Crystal structure of the CysR-CTLD2 fragment of human MR at acidic pH

PDB ID 5xtw

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