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5yg2

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==Plasmodium vivax SHMT bound with PLP-glycine and GS705==
==Plasmodium vivax SHMT bound with PLP-glycine and GS705==
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<StructureSection load='5yg2' size='340' side='right' caption='[[5yg2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='5yg2' size='340' side='right'caption='[[5yg2]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5yg2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YG2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YG2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5yg2]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YG2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YG2 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=N05:3-[1-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-fluoranyl-phenyl]piperidin-4-yl]propanoic+acid'>N05</scene>, <scene name='pdbligand=PLG:N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]'>PLG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycine_hydroxymethyltransferase Glycine hydroxymethyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.2.1 2.1.2.1] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=N05:3-[1-[3-[(4~{S})-6-azanyl-5-cyano-3-methyl-4-propan-2-yl-2~{H}-pyrano[2,3-c]pyrazol-4-yl]-5-fluoranyl-phenyl]piperidin-4-yl]propanoic+acid'>N05</scene>, <scene name='pdbligand=PLG:N-GLYCINE-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE]'>PLG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yg2 OCA], [http://pdbe.org/5yg2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yg2 RCSB], [http://www.ebi.ac.uk/pdbsum/5yg2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yg2 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yg2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yg2 OCA], [https://pdbe.org/5yg2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yg2 RCSB], [https://www.ebi.ac.uk/pdbsum/5yg2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yg2 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A1G4H5I1_PLAVI A0A1G4H5I1_PLAVI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5yg2" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5yg2" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Serine hydroxymethyltransferase 3D structures|Serine hydroxymethyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Glycine hydroxymethyltransferase]]
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[[Category: Large Structures]]
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[[Category: Chitnumsub, P]]
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[[Category: Plasmodium vivax]]
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[[Category: Diederich, F]]
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[[Category: Chitnumsub P]]
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[[Category: Jaruwat, A]]
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[[Category: Diederich F]]
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[[Category: Leartsakulpanich, U]]
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[[Category: Jaruwat A]]
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[[Category: Schwertz, G]]
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[[Category: Leartsakulpanich U]]
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[[Category: Alpha and beta protein]]
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[[Category: Schwertz G]]
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[[Category: Inhibitor]]
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[[Category: Methyltransferase activity]]
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[[Category: Transferase]]
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[[Category: Transferase-inhibitor complex]]
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Current revision

Plasmodium vivax SHMT bound with PLP-glycine and GS705

PDB ID 5yg2

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