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5yhf

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Current revision (08:29, 22 November 2023) (edit) (undo)
 
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==Crystal structure of SecDF in Super-membrane-facing form==
==Crystal structure of SecDF in Super-membrane-facing form==
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<StructureSection load='5yhf' size='340' side='right' caption='[[5yhf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='5yhf' size='340' side='right'caption='[[5yhf]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5yhf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thet8 Thet8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YHF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5YHF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5yhf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5YHF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5YHF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">secDF, TTHA0697 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=300852 THET8])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5yhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yhf OCA], [http://pdbe.org/5yhf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5yhf RCSB], [http://www.ebi.ac.uk/pdbsum/5yhf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5yhf ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5yhf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5yhf OCA], [https://pdbe.org/5yhf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5yhf RCSB], [https://www.ebi.ac.uk/pdbsum/5yhf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5yhf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SECDF_THET8 SECDF_THET8]] Conducts protons, which can be regulated by a proton gradient or by binding of an unfolded protein. Proton conduction requires the large periplasmic domain of the SecD.[HAMAP-Rule:MF_01463_B] Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.[HAMAP-Rule:MF_01463_B]
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[https://www.uniprot.org/uniprot/SECDF_THET8 SECDF_THET8] Conducts protons, which can be regulated by a proton gradient or by binding of an unfolded protein. Proton conduction requires the large periplasmic domain of the SecD.[HAMAP-Rule:MF_01463_B] Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.[HAMAP-Rule:MF_01463_B]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thet8]]
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[[Category: Large Structures]]
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[[Category: Furukawa, A]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Tanaka, Y]]
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[[Category: Furukawa A]]
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[[Category: Tsukazaki, T]]
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[[Category: Tanaka Y]]
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[[Category: Yoshikaie, K]]
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[[Category: Tsukazaki T]]
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[[Category: Beta barrel]]
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[[Category: Yoshikaie K]]
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[[Category: Membrane protein]]
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[[Category: Motor protein]]
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[[Category: Transport protein]]
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Current revision

Crystal structure of SecDF in Super-membrane-facing form

PDB ID 5yhf

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