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5zdr

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Current revision (08:52, 22 November 2023) (edit) (undo)
 
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<StructureSection load='5zdr' size='340' side='right'caption='[[5zdr]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
<StructureSection load='5zdr' size='340' side='right'caption='[[5zdr]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5zdr]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Trybb Trybb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZDR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ZDR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5zdr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei_brucei Trypanosoma brucei brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ZDR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ZDR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CHW:3-CHLORO-4,6-DIHYDROXY-5-[(2E,6E,8S)-8-HYDROXY-3,7-DIMETHYLNONA-2,6-DIEN-1-YL]-2-METHYLBENZALDEHYDE'>CHW</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=OH:HYDROXIDE+ION'>OH</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.59&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3vva|3vva]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CHW:3-CHLORO-4,6-DIHYDROXY-5-[(2E,6E,8S)-8-HYDROXY-3,7-DIMETHYLNONA-2,6-DIEN-1-YL]-2-METHYLBENZALDEHYDE'>CHW</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=OH:HYDROXIDE+ION'>OH</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AOX ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5702 TRYBB])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5zdr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zdr OCA], [https://pdbe.org/5zdr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5zdr RCSB], [https://www.ebi.ac.uk/pdbsum/5zdr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5zdr ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5zdr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5zdr OCA], [http://pdbe.org/5zdr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5zdr RCSB], [http://www.ebi.ac.uk/pdbsum/5zdr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5zdr ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AOX_TRYBB AOX_TRYBB]] Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.
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[https://www.uniprot.org/uniprot/AOX_TRYBB AOX_TRYBB] Catalyzes cyanide-resistant oxygen consumption. May increase respiration when the cytochrome respiratory pathway is restricted, or in response to low temperatures.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Trybb]]
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[[Category: Trypanosoma brucei brucei]]
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[[Category: Balogun, E O]]
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[[Category: Balogun EO]]
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[[Category: Harada, S]]
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[[Category: Harada S]]
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[[Category: Honma, T]]
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[[Category: Honma T]]
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[[Category: Inaoka, D K]]
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[[Category: Inaoka DK]]
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[[Category: Inoue, M]]
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[[Category: Inoue M]]
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[[Category: Kido, Y]]
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[[Category: Kido Y]]
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[[Category: Kita, K]]
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[[Category: Kita K]]
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[[Category: Moore, A L]]
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[[Category: Moore AL]]
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[[Category: Nara, T]]
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[[Category: Nara T]]
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[[Category: Saimoto, H]]
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[[Category: Saimoto H]]
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[[Category: Shiba, T]]
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[[Category: Shiba T]]
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[[Category: Takahashi, G]]
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[[Category: Takahashi G]]
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[[Category: Tanaka, A]]
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[[Category: Tanaka A]]
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[[Category: Tsuge, C]]
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[[Category: Tsuge C]]
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[[Category: Ueda, S]]
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[[Category: Ueda S]]
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[[Category: Young, L]]
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[[Category: Young L]]
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[[Category: Membrane bound diiron protein]]
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[[Category: Membrane protein]]
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[[Category: Oxidoreductase]]
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Current revision

Crystal structure of cyanide-insensitive alternative oxidase from Trypanosoma brucei with ascofuranone derivative

PDB ID 5zdr

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OCA

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