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6a4m

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Current revision (09:18, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6a4m' size='340' side='right'caption='[[6a4m]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='6a4m' size='340' side='right'caption='[[6a4m]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6a4m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacsu Bacsu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6A4M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6a4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis_subsp._subtilis_str._168 Bacillus subtilis subsp. subtilis str. 168]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6A4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6A4M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pucL, yunL, BSU32450 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224308 BACSU])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6a4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a4m OCA], [http://pdbe.org/6a4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6a4m RCSB], [http://www.ebi.ac.uk/pdbsum/6a4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6a4m ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6a4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6a4m OCA], [https://pdbe.org/6a4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6a4m RCSB], [https://www.ebi.ac.uk/pdbsum/6a4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6a4m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PUCL_BACSU PUCL_BACSU]] Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.<ref>PMID:11344136</ref> <ref>PMID:17567580</ref> <ref>PMID:20168977</ref>
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[https://www.uniprot.org/uniprot/PUCL_BACSU PUCL_BACSU] Catalyzes two steps in the degradation of uric acid, i.e. the oxidation of uric acid to 5-hydroxyisourate (HIU) and the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin.<ref>PMID:11344136</ref> <ref>PMID:17567580</ref> <ref>PMID:20168977</ref>
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==See Also==
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*[[Urate oxidase 3D structures|Urate oxidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacsu]]
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[[Category: Bacillus subtilis subsp. subtilis str. 168]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Jiang, Y Y]]
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[[Category: Jiang YY]]
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[[Category: Bacillus subtili]]
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[[Category: Hydrolase]]
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[[Category: Uricase]]
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Current revision

Structure of urate oxidase from Bacillus subtilis 168

PDB ID 6a4m

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