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6aca

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Current revision (09:25, 22 November 2023) (edit) (undo)
 
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<StructureSection load='6aca' size='340' side='right'caption='[[6aca]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
<StructureSection load='6aca' size='340' side='right'caption='[[6aca]], [[Resolution|resolution]] 3.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[6aca]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ACA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ACA FirstGlance]. <br>
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<table><tr><td colspan='2'>[[6aca]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6ACA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6ACA FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6aca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aca OCA], [http://pdbe.org/6aca PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6aca RCSB], [http://www.ebi.ac.uk/pdbsum/6aca PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6aca ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6aca FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6aca OCA], [https://pdbe.org/6aca PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6aca RCSB], [https://www.ebi.ac.uk/pdbsum/6aca PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6aca ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MFD_MYCTU MFD_MYCTU]] Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.[HAMAP-Rule:MF_00969]
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[https://www.uniprot.org/uniprot/MFD_MYCTU MFD_MYCTU] Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.[HAMAP-Rule:MF_00969]
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==See Also==
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*[[Transcription-repair coupling factor 3D structures|Transcription-repair coupling factor 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Fox, G C]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Nagaraja, V]]
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[[Category: Fox GC]]
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[[Category: Natesh, R]]
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[[Category: Nagaraja V]]
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[[Category: Putta, S]]
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[[Category: Natesh R]]
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[[Category: Rao, D N]]
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[[Category: Putta S]]
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[[Category: Walsh, M A]]
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[[Category: Rao DN]]
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[[Category: Hydrolase]]
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[[Category: Walsh MA]]
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[[Category: Mfd]]
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[[Category: Transcription coupled nucleotide excision repair]]
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[[Category: Transcription regulation]]
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[[Category: Transcription repair coupling factor]]
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Current revision

Crystal structure of Mycobacterium tuberculosis Mfd at 3.6 A resolution

PDB ID 6aca

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