This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
6le3
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 6le3 is ON HOLD Authors: Yuan, H. Description: Crystal structure of gluconate 5-dehydrogenase from Lentibacter algarum [[Category: Unreleased Struc...) |
|||
| (3 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of gluconate 5-dehydrogenase from Lentibacter algarum== | |
| + | <StructureSection load='6le3' size='340' side='right'caption='[[6le3]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[6le3]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Lentibacter_algarum Lentibacter algarum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LE3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6LE3 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6le3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6le3 OCA], [https://pdbe.org/6le3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6le3 RCSB], [https://www.ebi.ac.uk/pdbsum/6le3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6le3 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A1H3NGY9_9RHOB A0A1H3NGY9_9RHOB] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Gluconate 5-dehydrogenase (Ga5DH; EC 1.1.1.69) from Lentibacter algarum (LaGa5DH) was recombinantly expressed in Escherichia coli and purified to homogeneity. The protein was crystallized and the crystal structure was solved at 2.1 A resolution. The crystal belonged to the monoclinic system, with space group P1 and unit-cell parameters a = 55.42, b = 55.48, c = 79.16 A, alpha = 100.51, beta = 105.66, gamma = 97.99 degrees . The structure revealed LaGaDH to be a tetramer, with each subunit consisting of six alpha-helices and three antiparallel beta-hairpins. LaGa5DH has high structural similarity to other Ga5DH proteins, demonstrating that this enzyme is highly conserved. | ||
| - | + | Crystal structure of gluconate 5-dehydrogenase from Lentibacter algarum.,Tian D, Fu X, Cao W, Yuan H Acta Crystallogr F Struct Biol Commun. 2020 May 1;76(Pt 5):228-234. doi:, 10.1107/S2053230X20005336. Epub 2020 Apr 29. PMID:32356525<ref>PMID:32356525</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | [[Category: | + | </div> |
| - | [[Category: Yuan | + | <div class="pdbe-citations 6le3" style="background-color:#fffaf0;"></div> |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Lentibacter algarum]] | ||
| + | [[Category: Yuan H]] | ||
Current revision
Crystal structure of gluconate 5-dehydrogenase from Lentibacter algarum
| |||||||||||
