This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
7zvf
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7zvf is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures) |
|||
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human cathepsin L in complex with covalently bound CLIK148== | |
| - | + | <StructureSection load='7zvf' size='340' side='right'caption='[[7zvf]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7zvf]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7ZVF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7ZVF FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=KXL:(2S)-N-[(2S)-1-(dimethylamino)-1-oxidanylidene-3-phenyl-propan-2-yl]-2-oxidanyl-N-(2-pyridin-2-ylethyl)butanediamide'>KXL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7zvf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7zvf OCA], [https://pdbe.org/7zvf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7zvf RCSB], [https://www.ebi.ac.uk/pdbsum/7zvf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7zvf ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chapman HN]] | ||
| + | [[Category: Ewert W]] | ||
| + | [[Category: Falke S]] | ||
| + | [[Category: Guenther S]] | ||
| + | [[Category: Hinrichs W]] | ||
| + | [[Category: Karnicar K]] | ||
| + | [[Category: Lieske J]] | ||
| + | [[Category: Lindic N]] | ||
| + | [[Category: Loboda J]] | ||
| + | [[Category: Meents A]] | ||
| + | [[Category: Reinke PYA]] | ||
| + | [[Category: Sekirnik A]] | ||
| + | [[Category: Tsuge H]] | ||
| + | [[Category: Turk D]] | ||
| + | [[Category: Usenik A]] | ||
Current revision
Crystal structure of human cathepsin L in complex with covalently bound CLIK148
| |||||||||||
Categories: Homo sapiens | Large Structures | Chapman HN | Ewert W | Falke S | Guenther S | Hinrichs W | Karnicar K | Lieske J | Lindic N | Loboda J | Meents A | Reinke PYA | Sekirnik A | Tsuge H | Turk D | Usenik A
