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7bqw
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of Methionine gamma-lyase from Fusobacterium nucleatum== | |
| + | <StructureSection load='7bqw' size='340' side='right'caption='[[7bqw]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7bqw]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Fusobacterium_nucleatum_subsp._nucleatum_ATCC_25586 Fusobacterium nucleatum subsp. nucleatum ATCC 25586]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7BQW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7BQW FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7bqw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7bqw OCA], [https://pdbe.org/7bqw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7bqw RCSB], [https://www.ebi.ac.uk/pdbsum/7bqw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7bqw ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MEGL_FUSNN MEGL_FUSNN] Catalyzes the alpha,gamma-elimination of L-methionine to produce methanethiol, 2-oxobutanoate and ammonia, and that of L-homocysteine (By similarity). Can also use L-cysteine as substrate, catalyzing its alpha,beta-elimination; this activity seems to only minimally contribute to the production of hydrogen sulfide (H2S) by F.nucleatum in the oral cavity, which is toxic for a large variety of cells in periodontal regions (PubMed:21798982).[UniProtKB:Q8L0X4]<ref>PMID:21798982</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Methionine gamma-lyase 3D structures|Methionine gamma-lyase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Fusobacterium nucleatum subsp. nucleatum ATCC 25586]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| + | [[Category: Chen Y]] | ||
| + | [[Category: Lan J]] | ||
| + | [[Category: Liu W]] | ||
| + | [[Category: Xu Y]] | ||
Current revision
Crystal structure of Methionine gamma-lyase from Fusobacterium nucleatum
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