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7c3o
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of TT109 from CANDIDA ALBICANS== | |
| + | <StructureSection load='7c3o' size='340' side='right'caption='[[7c3o]], [[Resolution|resolution]] 1.89Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7c3o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans_SC5314 Candida albicans SC5314]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7C3O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7C3O FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.89Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACO:ACETYL+COENZYME+*A'>ACO</scene>, <scene name='pdbligand=ALY:N(6)-ACETYLLYSINE'>ALY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7c3o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7c3o OCA], [https://pdbe.org/7c3o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7c3o RCSB], [https://www.ebi.ac.uk/pdbsum/7c3o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7c3o ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/RT109_CANAL RT109_CANAL] Histone chaperone-dependent acetylase that modifies 'Lys-56' of histone H3 (H3K56ac), to promote genomic stability, DNA repair and transcriptional regulation during mitotic S-phase (PubMed:20601951, PubMed:20080646). Plays an important role in the regulation of white-opaque genotoxin induced-switching (PubMed:21749487).<ref>PMID:20080646</ref> <ref>PMID:20601951</ref> <ref>PMID:21749487</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Histone acetyltransferase 3D structures|Histone acetyltransferase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Candida albicans SC5314]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chen YP]] | ||
| + | [[Category: Lei JH]] | ||
| + | [[Category: Lu DR]] | ||
| + | [[Category: Su D]] | ||
Current revision
Crystal structure of TT109 from CANDIDA ALBICANS
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