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7dkl

From Proteopedia

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Current revision (16:35, 29 November 2023) (edit) (undo)
 
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<StructureSection load='7dkl' size='340' side='right'caption='[[7dkl]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='7dkl' size='340' side='right'caption='[[7dkl]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[7dkl]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DKL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DKL FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7dkl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DKL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DKL FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dkl OCA], [https://pdbe.org/7dkl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dkl RCSB], [https://www.ebi.ac.uk/pdbsum/7dkl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dkl ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7dkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7dkl OCA], [https://pdbe.org/7dkl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7dkl RCSB], [https://www.ebi.ac.uk/pdbsum/7dkl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7dkl ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DPTOR_HUMAN DPTOR_HUMAN]] Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.<ref>PMID:19446321</ref>
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[https://www.uniprot.org/uniprot/DPTOR_HUMAN DPTOR_HUMAN] Negative regulator of the mTORC1 and mTORC2 signaling pathways. Inhibits the kinase activity of both complexes.<ref>PMID:19446321</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Liu, Y F]]
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[[Category: Liu YF]]
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[[Category: Shen, X X]]
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[[Category: Shen XX]]
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[[Category: Weng, Z F]]
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[[Category: Weng ZF]]
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[[Category: Anionic lipid binding protein]]
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[[Category: Dep domain]]
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[[Category: Lipid binding protein]]
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[[Category: Mtor inhibitor]]
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[[Category: Pa binding protein]]
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Current revision

Crystal structure of the tandem DEP domains of DEPTOR

PDB ID 7dkl

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OCA

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