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7e3d
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human acetylcholinesterase== | |
| + | <StructureSection load='7e3d' size='340' side='right'caption='[[7e3d]], [[Resolution|resolution]] 2.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7e3d]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7E3D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7E3D FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PE8:3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL'>PE8</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7e3d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7e3d OCA], [https://pdbe.org/7e3d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7e3d RCSB], [https://www.ebi.ac.uk/pdbsum/7e3d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7e3d ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ACES_HUMAN ACES_HUMAN] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis.<ref>PMID:2714437</ref> <ref>PMID:1748670</ref> <ref>PMID:1517212</ref> <ref>PMID:11985878</ref> | ||
| - | + | ==See Also== | |
| - | + | *[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Hanada | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Mishima-Tsumagari | + | [[Category: Dileep KV]] |
| - | [[Category: | + | [[Category: Hanada K]] |
| - | [[Category: | + | [[Category: Ihara K]] |
| - | [[Category: | + | [[Category: Kukimoto-Niino M]] |
| + | [[Category: Mishima-Tsumagari C]] | ||
| + | [[Category: Shirouzu M]] | ||
| + | [[Category: Yonemochi M]] | ||
| + | [[Category: Zhang KYJ]] | ||
Current revision
Crystal structure of human acetylcholinesterase
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