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7ezt

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'''Unreleased structure'''
 
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The entry 7ezt is ON HOLD until Dec 30 2023
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==The structure and functional mechanism of nucleotide regulated acetylhexosaminidase Am2136 from Akkermansia muciniphila==
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<StructureSection load='7ezt' size='340' side='right'caption='[[7ezt]], [[Resolution|resolution]] 2.81&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7ezt]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Akkermansia_muciniphila_ATCC_BAA-835 Akkermansia muciniphila ATCC BAA-835]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7EZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7EZT FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.81&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ezt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ezt OCA], [https://pdbe.org/7ezt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ezt RCSB], [https://www.ebi.ac.uk/pdbsum/7ezt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ezt ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/H2136_AKKM8 H2136_AKKM8] Potentially capable of cleaving the specific glycoside linkages in the process of mucin degradation in human intestinal tract (Probable). Hydrolyzes synthetic substrate pNP-beta-GlcNAc with high activity and pNP-beta-GalNAc to a lot lesser extent. Does not hydrolyze pNP-alpha-GalNAc.<ref>PMID:31345574</ref>
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Authors:
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==See Also==
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*[[Beta-N-acetylhexosaminidase 3D structures|Beta-N-acetylhexosaminidase 3D structures]]
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Description:
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== References ==
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[[Category: Unreleased Structures]]
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Akkermansia muciniphila ATCC BAA-835]]
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[[Category: Large Structures]]
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[[Category: Bao R]]
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[[Category: Huang Q]]
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[[Category: Li CC]]
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[[Category: Liu TG]]
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[[Category: Luo GH]]
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[[Category: Mou XY]]
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[[Category: Song YJ]]
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[[Category: Tang XY]]
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[[Category: Zhao NL]]
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[[Category: Zhu YB]]

Current revision

The structure and functional mechanism of nucleotide regulated acetylhexosaminidase Am2136 from Akkermansia muciniphila

PDB ID 7ezt

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