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7v5s
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of human bleomycin hydrolase C73A mutant== | |
| - | + | <StructureSection load='7v5s' size='340' side='right'caption='[[7v5s]], [[Resolution|resolution]] 3.02Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7v5s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7V5S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7V5S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.02Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7v5s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7v5s OCA], [https://pdbe.org/7v5s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7v5s RCSB], [https://www.ebi.ac.uk/pdbsum/7v5s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7v5s ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: Huang | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/BLMH_HUMAN BLMH_HUMAN] The normal physiological role of BLM hydrolase is unknown, but it catalyzes the inactivation of the antitumor drug BLM (a glycopeptide) by hydrolyzing the carboxamide bond of its B-aminoalaninamide moiety thus protecting normal and malignant cells from BLM toxicity (By similarity). |
| - | [[Category: Toh | + | __TOC__ |
| - | [[Category: Wang | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chang CY]] | ||
| + | [[Category: Huang SJ]] | ||
| + | [[Category: Lin EC]] | ||
| + | [[Category: Toh SI]] | ||
| + | [[Category: Wang YL]] | ||
| + | [[Category: Zheng YZ]] | ||
Current revision
Crystal structure of human bleomycin hydrolase C73A mutant
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Categories: Homo sapiens | Large Structures | Chang CY | Huang SJ | Lin EC | Toh SI | Wang YL | Zheng YZ
