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7wvb
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7wvb is ON HOLD Authors: Chen, Y., Zhang, J., Li, C., Cao, Y. Description: Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state [[Categor...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state== | |
| + | <StructureSection load='7wvb' size='340' side='right'caption='[[7wvb]], [[Resolution|resolution]] 2.09Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[7wvb]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7WVB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7WVB FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.09Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7wvb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7wvb OCA], [https://pdbe.org/7wvb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7wvb RCSB], [https://www.ebi.ac.uk/pdbsum/7wvb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7wvb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/F16P1_HUMAN F16P1_HUMAN] Defects in FBP1 are the cause of fructose-1,6-bisphosphatase deficiency (FBPD) [MIM:[https://omim.org/entry/229700 229700]. FBPD is inherited as an autosomal recessive disorder mainly in the liver and causes life-threatening episodes of hypoglycemia and metabolic acidosis (lactacidemia) in newborn infants or young children.<ref>PMID:9382095</ref> <ref>PMID:12126934</ref> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/F16P1_HUMAN F16P1_HUMAN] | ||
| - | + | ==See Also== | |
| - | + | *[[Fructose-1%2C6-bisphosphatase 3D structures|Fructose-1%2C6-bisphosphatase 3D structures]] | |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Chen | + | </StructureSection> |
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: Zhang | + | [[Category: Large Structures]] |
| + | [[Category: Cao Y]] | ||
| + | [[Category: Chen Y]] | ||
| + | [[Category: Li C]] | ||
| + | [[Category: Zhang J]] | ||
Current revision
Human Fructose-1,6-bisphosphatase 1 mutant R50A in APO R-state
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Categories: Homo sapiens | Large Structures | Cao Y | Chen Y | Li C | Zhang J
