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7y3m
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | The entry | + | ==Structure of SALL4 ZFC1 bound with 16 bp AT-rich dsDNA== |
| - | + | <StructureSection load='7y3m' size='340' side='right'caption='[[7y3m]], [[Resolution|resolution]] 2.72Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7y3m]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Y3M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Y3M FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.723Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7y3m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7y3m OCA], [https://pdbe.org/7y3m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7y3m RCSB], [https://www.ebi.ac.uk/pdbsum/7y3m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7y3m ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/SALL4_HUMAN SALL4_HUMAN] Acro-renal-ocular syndrome;IVIC syndrome;Okihiro syndrome due to 20q13 microdeletion;Okihiro syndrome due to a point mutation. The disease is caused by mutations affecting the gene represented in this entry. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SALL4_HUMAN SALL4_HUMAN] Transcription factor with a key role in the maintenance and self-renewal of embryonic and hematopoietic stem cells.<ref>PMID:23012367</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Ru W]] | ||
| + | [[Category: Xu C]] | ||
Current revision
Structure of SALL4 ZFC1 bound with 16 bp AT-rich dsDNA
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