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4gfu
From Proteopedia
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==PTPN18 in complex with HER2-pY1248 phosphor-peptides== | ==PTPN18 in complex with HER2-pY1248 phosphor-peptides== | ||
| - | <StructureSection load='4gfu' size='340' side='right' caption='[[4gfu]], [[Resolution|resolution]] 2.00Å' scene=''> | + | <StructureSection load='4gfu' size='340' side='right'caption='[[4gfu]], [[Resolution|resolution]] 2.00Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4gfu]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4gfu]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GFU FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gfu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gfu OCA], [https://pdbe.org/4gfu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gfu RCSB], [https://www.ebi.ac.uk/pdbsum/4gfu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gfu ProSAT]</span></td></tr> |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PTN18_HUMAN PTN18_HUMAN] Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues. | ||
==See Also== | ==See Also== | ||
| - | *[[Tyrosine phosphatase|Tyrosine phosphatase]] | + | *[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] |
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Du | + | [[Category: Du YJ]] |
| - | [[Category: Sun | + | [[Category: Sun JP]] |
| - | [[Category: Wang | + | [[Category: Wang HM]] |
| - | [[Category: Yang | + | [[Category: Yang DX]] |
| - | [[Category: Yang | + | [[Category: Yang F]] |
| - | [[Category: Yu | + | [[Category: Yu X]] |
| - | [[Category: Zhang | + | [[Category: Zhang Y]] |
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Current revision
PTPN18 in complex with HER2-pY1248 phosphor-peptides
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Categories: Homo sapiens | Large Structures | Du YJ | Sun JP | Wang HM | Yang DX | Yang F | Yu X | Zhang Y
