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4gfv
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==PTPN18 in complex with HER2-pY1196 phosphor-peptides== | |
| + | <StructureSection load='4gfv' size='340' side='right'caption='[[4gfv]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[4gfv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GFV FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.095Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gfv OCA], [https://pdbe.org/4gfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gfv RCSB], [https://www.ebi.ac.uk/pdbsum/4gfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gfv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/PTN18_HUMAN PTN18_HUMAN] Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues. | ||
| - | + | ==See Also== | |
| - | + | *[[Tyrosine phosphatase 3D structures|Tyrosine phosphatase 3D structures]] | |
| - | + | __TOC__ | |
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Du YJ]] | ||
| + | [[Category: Sun JP]] | ||
| + | [[Category: Wang HM]] | ||
| + | [[Category: Yang DX]] | ||
| + | [[Category: Yang F]] | ||
| + | [[Category: Yu X]] | ||
| + | [[Category: Zhang Y]] | ||
Current revision
PTPN18 in complex with HER2-pY1196 phosphor-peptides
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Categories: Homo sapiens | Large Structures | Du YJ | Sun JP | Wang HM | Yang DX | Yang F | Yu X | Zhang Y
