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4ghm
From Proteopedia
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| - | [[Image:4ghm.jpg|left|200px]] | ||
| - | + | ==Crystal Structure of the H233A mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0== | |
| - | + | <StructureSection load='4ghm' size='340' side='right'caption='[[4ghm]], [[Resolution|resolution]] 1.62Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[4ghm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3rzq 3rzq]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GHM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GHM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.618Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=PRF:7-DEAZA-7-AMINOMETHYL-GUANINE'>PRF</scene></td></tr> |
| - | [[4ghm]] is a 2 chain structure with sequence from [ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ghm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ghm OCA], [https://pdbe.org/4ghm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ghm RCSB], [https://www.ebi.ac.uk/pdbsum/4ghm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ghm ProSAT]</span></td></tr> |
| - | [ | + | </table> |
| - | [[ | + | == Function == |
| - | [[ | + | [https://www.uniprot.org/uniprot/QUEF_VIBCH QUEF_VIBCH] Catalyzes the NADPH-dependent reduction of 7-cyano-7-deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity). |
| - | [[ | + | __TOC__ |
| - | [ | + | </StructureSection> |
| - | [ | + | [[Category: Large Structures]] |
| - | [ | + | [[Category: Vibrio cholerae O1 biovar El Tor str. N16961]] |
| - | [ | + | [[Category: Anderson WF]] |
| - | [[Category: | + | [[Category: Gu M]] |
| - | [[Category: | + | [[Category: Joachimiak A]] |
| - | [[Category: | + | [[Category: Kim Y]] |
| - | [[Category: | + | [[Category: Zhou M]] |
| - | [[Category: | + | |
| - | [[Category: | + | |
| - | [[Category: | + | |
Current revision
Crystal Structure of the H233A mutant of 7-cyano-7-deazaguanine reductase, QueF from Vibrio cholerae complexed with preQ0
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