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1sso
From Proteopedia
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| - | [[Image:1sso.png|left|200px]] | ||
| - | + | ==SOLUTION STRUCTURE AND DNA-BINDING PROPERTIES OF A THERMOSTABLE PROTEIN FROM THE ARCHAEON SULFOLOBUS SOLFATARICUS== | |
| + | <StructureSection load='1sso' size='340' side='right'caption='[[1sso]]' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1sso]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SSO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SSO FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sso FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sso OCA], [https://pdbe.org/1sso PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sso RCSB], [https://www.ebi.ac.uk/pdbsum/1sso PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sso ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DN7A_SACS2 DN7A_SACS2] | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | The archaeon Sulfolobus solfataricus expresses large amounts of a small basic protein, Sso7d, which was previously identified as a DNA-binding protein possibly involved in compaction of DNA. We have determined the solution structure of Sso7d. The protein consists of a triple-stranded anti-parallel beta-sheet onto which an orthogonal double-stranded beta-sheet is packed. This topology is very similar to that found in eukaryotic Src homology-3 (SH3) domains. Sso7d binds strongly (Kd < 10 microM) to double-stranded DNA and protects it from thermal denaturation. In addition, we note that epsilon-mono-methylation of lysine side chains of Sso7d is governed by cell growth temperatures, suggesting that methylation is related to the heat-shock response. | ||
| - | + | Solution structure and DNA-binding properties of a thermostable protein from the archaeon Sulfolobus solfataricus.,Baumann H, Knapp S, Lundback T, Ladenstein R, Hard T Nat Struct Biol. 1994 Nov;1(11):808-19. PMID:7634092<ref>PMID:7634092</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | == | + | <div class="pdbe-citations 1sso" style="background-color:#fffaf0;"></div> |
| - | + | == References == | |
| - | [[Category: | + | <references/> |
| - | [[Category: Baumann | + | __TOC__ |
| - | [[Category: Hard | + | </StructureSection> |
| - | [[Category: Knapp | + | [[Category: Large Structures]] |
| - | [[Category: Ladenstein | + | [[Category: Saccharolobus solfataricus]] |
| - | [[Category: Lundback | + | [[Category: Baumann H]] |
| - | + | [[Category: Hard T]] | |
| + | [[Category: Knapp S]] | ||
| + | [[Category: Ladenstein R]] | ||
| + | [[Category: Lundback T]] | ||
Current revision
SOLUTION STRUCTURE AND DNA-BINDING PROPERTIES OF A THERMOSTABLE PROTEIN FROM THE ARCHAEON SULFOLOBUS SOLFATARICUS
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