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1wi0
From Proteopedia
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==Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)== | ==Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)== | ||
| - | <StructureSection load='1wi0' size='340' side='right' caption='[[1wi0 | + | <StructureSection load='1wi0' size='340' side='right'caption='[[1wi0]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1wi0]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1wi0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WI0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WI0 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wi0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wi0 OCA], [https://pdbe.org/1wi0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wi0 RCSB], [https://www.ebi.ac.uk/pdbsum/1wi0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wi0 ProSAT], [https://www.topsan.org/Proteins/RSGI/1wi0 TOPSAN]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/MP2K5_MOUSE MP2K5_MOUSE] Acts as a scaffold for the formation of a ternary MAP3K2/MAP3K3-MAP3K5-MAPK7 signaling complex. Activation of this pathway appears to play a critical role in protecting cells from stress-induced apoptosis, neuronal survival and cardiac development and angiogenesis.<ref>PMID:10473620</ref> <ref>PMID:16507987</ref> |
==See Also== | ==See Also== | ||
| - | *[[Mitogen-activated protein kinase kinase|Mitogen-activated protein kinase kinase]] | + | *[[Mitogen-activated protein kinase kinase 3D structures|Mitogen-activated protein kinase kinase 3D structures]] |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Hayashi | + | [[Category: Mus musculus]] |
| - | [[Category: Inoue | + | [[Category: Hayashi F]] |
| - | [[Category: Kigawa | + | [[Category: Inoue M]] |
| - | [[Category: Koshiba | + | [[Category: Kigawa T]] |
| - | + | [[Category: Koshiba S]] | |
| - | [[Category: Tochio | + | [[Category: Tochio N]] |
| - | [[Category: Yokoyama | + | [[Category: Yokoyama S]] |
| - | [[Category: Yoneyama | + | [[Category: Yoneyama M]] |
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Current revision
Solution structure of the PB1 domain of mouse mitogen activated protein kinase kinase 5 (MAP2K5)
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Categories: Large Structures | Mus musculus | Hayashi F | Inoue M | Kigawa T | Koshiba S | Tochio N | Yokoyama S | Yoneyama M
