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1xzy

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==Solution structure of the P30-trans form of Alpha Hemoglobin Stabilizing Protein (AHSP)==
==Solution structure of the P30-trans form of Alpha Hemoglobin Stabilizing Protein (AHSP)==
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<StructureSection load='1xzy' size='340' side='right'caption='[[1xzy]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
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<StructureSection load='1xzy' size='340' side='right'caption='[[1xzy]]' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1xzy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZY OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1XZY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1xzy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XZY FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1w09|1w09]], [[1w0a|1w0a]], [[1w0b|1w0b]]</div></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AHSP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzy OCA], [https://pdbe.org/1xzy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xzy RCSB], [https://www.ebi.ac.uk/pdbsum/1xzy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzy ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1xzy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xzy OCA], [http://pdbe.org/1xzy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xzy RCSB], [http://www.ebi.ac.uk/pdbsum/1xzy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xzy ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AHSP_HUMAN AHSP_HUMAN]] Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.<ref>PMID:12066189</ref>
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[https://www.uniprot.org/uniprot/AHSP_HUMAN AHSP_HUMAN] Acts as a chaperone to prevent the harmful aggregation of alpha-hemoglobin during normal erythroid cell development. Specifically protects free alpha-hemoglobin from precipitation. It is predicted to modulate pathological states of alpha-hemoglobin excess such as beta-thalassemia.<ref>PMID:12066189</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Feng, L]]
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[[Category: Feng L]]
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[[Category: Gell, D A]]
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[[Category: Gell DA]]
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[[Category: Kong, Y]]
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[[Category: Kong Y]]
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[[Category: Lee, C]]
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[[Category: Lee C]]
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[[Category: Mackay, J P]]
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[[Category: Mackay JP]]
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[[Category: Shi, Y]]
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[[Category: Shi Y]]
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[[Category: Weiss, M J]]
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[[Category: Weiss MJ]]
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[[Category: Zhou, S]]
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[[Category: Zhou S]]
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[[Category: Chaperone]]
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[[Category: Helical bundle]]
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[[Category: Three-helix bundle]]
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Current revision

Solution structure of the P30-trans form of Alpha Hemoglobin Stabilizing Protein (AHSP)

PDB ID 1xzy

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