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5och

From Proteopedia

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(New page: '''Unreleased structure''' The entry 5och is ON HOLD until Paper Publication Authors: Description: Category: Unreleased Structures)
Current revision (09:39, 6 December 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 5och is ON HOLD until Paper Publication
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==The crystal structure of human ABCB8 in an outward-facing state==
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<StructureSection load='5och' size='340' side='right'caption='[[5och]], [[Resolution|resolution]] 3.40&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[5och]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OCH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OCH FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene>, <scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5och FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5och OCA], [https://pdbe.org/5och PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5och RCSB], [https://www.ebi.ac.uk/pdbsum/5och PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5och ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MITOS_HUMAN MITOS_HUMAN] ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane (PubMed:31435016). Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (PubMed:31435016). Plays a role in mitochondrial iron transport (PubMed:30623799). Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (By similarity).[UniProtKB:Q9CXJ4]<ref>PMID:30623799</ref> <ref>PMID:31435016</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith CH]]
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[[Category: Barr A]]
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[[Category: Borkowska O]]
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[[Category: Bountra C]]
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[[Category: Burgess-Brown NA]]
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[[Category: Carpenter EP]]
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[[Category: Chalk R]]
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[[Category: Chu A]]
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[[Category: Edwards AM]]
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[[Category: Faust B]]
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[[Category: Mukhopadhyay S]]
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[[Category: Pike ACW]]
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[[Category: Quiqley AM]]
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[[Category: Shintre CA]]
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[[Category: Shrestha L]]

Current revision

The crystal structure of human ABCB8 in an outward-facing state

PDB ID 5och

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