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5och
From Proteopedia
(Difference between revisions)
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<StructureSection load='5och' size='340' side='right'caption='[[5och]], [[Resolution|resolution]] 3.40Å' scene=''> | <StructureSection load='5och' size='340' side='right'caption='[[5och]], [[Resolution|resolution]] 3.40Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5och]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OCH OCA]. For a <b>guided tour on the structure components</b> use [ | + | <table><tr><td colspan='2'>[[5och]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OCH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OCH FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene>, <scene name='pdbligand=YCM:S-(2-AMINO-2-OXOETHYL)-L-CYSTEINE'>YCM</scene></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5och FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5och OCA], [https://pdbe.org/5och PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5och RCSB], [https://www.ebi.ac.uk/pdbsum/5och PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5och ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/MITOS_HUMAN MITOS_HUMAN] ATP-binding subunit of the mitochondrial potassium channel located in the mitochondrial inner membrane (PubMed:31435016). Together with CCDC51/MITOK, forms a protein complex localized in the mitochondria that mediates ATP-dependent potassium currents across the inner membrane (that is, mitoK(ATP) channel) (PubMed:31435016). Plays a role in mitochondrial iron transport (PubMed:30623799). Required for maintenance of normal cardiac function, possibly by influencing mitochondrial iron export and regulating the maturation of cytosolic iron sulfur cluster-containing enzymes (By similarity).[UniProtKB:Q9CXJ4]<ref>PMID:30623799</ref> <ref>PMID:31435016</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Barr | + | [[Category: Barr A]] |
| - | [[Category: Borkowska | + | [[Category: Borkowska O]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Burgess-Brown | + | [[Category: Burgess-Brown NA]] |
| - | [[Category: Carpenter | + | [[Category: Carpenter EP]] |
| - | [[Category: Chalk | + | [[Category: Chalk R]] |
| - | [[Category: Chu | + | [[Category: Chu A]] |
| - | [[Category: Edwards | + | [[Category: Edwards AM]] |
| - | [[Category: Faust | + | [[Category: Faust B]] |
| - | [[Category: Mukhopadhyay | + | [[Category: Mukhopadhyay S]] |
| - | [[Category: Pike | + | [[Category: Pike ACW]] |
| - | [[Category: Quiqley | + | [[Category: Quiqley AM]] |
| - | + | [[Category: Shintre CA]] | |
| - | [[Category: Shintre | + | [[Category: Shrestha L]] |
| - | [[Category: Shrestha | + | |
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Current revision
The crystal structure of human ABCB8 in an outward-facing state
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Barr A | Borkowska O | Bountra C | Burgess-Brown NA | Carpenter EP | Chalk R | Chu A | Edwards AM | Faust B | Mukhopadhyay S | Pike ACW | Quiqley AM | Shintre CA | Shrestha L
