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1glo

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==Crystal Structure of Cys25Ser mutant of human cathepsin S==
==Crystal Structure of Cys25Ser mutant of human cathepsin S==
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<StructureSection load='1glo' size='340' side='right' caption='[[1glo]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='1glo' size='340' side='right'caption='[[1glo]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1glo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GLO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GLO FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1glo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GLO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GLO FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1bxf|1bxf]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cathepsin_S Cathepsin S], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.27 3.4.22.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1glo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1glo OCA], [https://pdbe.org/1glo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1glo RCSB], [https://www.ebi.ac.uk/pdbsum/1glo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1glo ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1glo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1glo OCA], [http://pdbe.org/1glo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1glo RCSB], [http://www.ebi.ac.uk/pdbsum/1glo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1glo ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN]] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
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[https://www.uniprot.org/uniprot/CATS_HUMAN CATS_HUMAN] Thiol protease. Key protease responsible for the removal of the invariant chain from MHC class II molecules. The bond-specificity of this proteinase is in part similar to the specificities of cathepsin L and cathepsin N.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1glo" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1glo" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Cathepsin 3D structures|Cathepsin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cathepsin S]]
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[[Category: Homo sapiens]]
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[[Category: Human]]
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[[Category: Large Structures]]
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[[Category: Brzozowski, A M]]
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[[Category: Brzozowski AM]]
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[[Category: Hubbard, R E]]
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[[Category: Hubbard RE]]
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[[Category: Lamers, M B.A C]]
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[[Category: Lamers MBAC]]
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[[Category: Sturt, S L]]
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[[Category: Sturt SL]]
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[[Category: Turkenburg, J P]]
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[[Category: Turkenburg JP]]
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[[Category: Williams, D H]]
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[[Category: Williams DH]]
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[[Category: Wright, L M]]
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[[Category: Wright LM]]
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[[Category: Cathepsin s]]
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[[Category: Hydrolase]]
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[[Category: Inhibitor]]
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[[Category: Proteinase]]
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[[Category: Thiol protea]]
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Current revision

Crystal Structure of Cys25Ser mutant of human cathepsin S

PDB ID 1glo

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