1gvd

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{{Seed}}
 
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[[Image:1gvd.png|left|200px]]
 
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==CRYSTAL STRUCTURE OF C-MYB R2 V103L MUTANT==
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The line below this paragraph, containing "STRUCTURE_1gvd", creates the "Structure Box" on the page.
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<StructureSection load='1gvd' size='340' side='right'caption='[[1gvd]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1gvd]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GVD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GVD FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1gvd| PDB=1gvd | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gvd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gvd OCA], [https://pdbe.org/1gvd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gvd RCSB], [https://www.ebi.ac.uk/pdbsum/1gvd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gvd ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MYB_MOUSE MYB_MOUSE] Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/gv/1gvd_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1gvd ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF C-MYB R2 V103L MUTANT===
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==See Also==
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*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1GVD is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GVD OCA].
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[[Category: Large Structures]]
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[[Category: Single protein]]
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[[Category: Mus musculus]]
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[[Category: Ogata, K.]]
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[[Category: Ogata K]]
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[[Category: Tahirov, T H.]]
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[[Category: Tahirov TH]]
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[[Category: C-myb]]
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[[Category: Dna binding]]
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[[Category: Ion binding]]
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[[Category: Myb]]
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[[Category: Nuclear protein]]
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[[Category: Proto-oncogene]]
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[[Category: Transcription]]
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[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 06:08:46 2008''
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Current revision

CRYSTAL STRUCTURE OF C-MYB R2 V103L MUTANT

PDB ID 1gvd

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