1gyw

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==Gamma-adaptin appendage domain from clathrin adaptor AP1 A753D mutant==
==Gamma-adaptin appendage domain from clathrin adaptor AP1 A753D mutant==
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<StructureSection load='1gyw' size='340' side='right' caption='[[1gyw]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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<StructureSection load='1gyw' size='340' side='right'caption='[[1gyw]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1gyw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GYW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1GYW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1gyw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1GYW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1GYW FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1gyu|1gyu]], [[1gyv|1gyv]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1gyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gyw OCA], [http://pdbe.org/1gyw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1gyw RCSB], [http://www.ebi.ac.uk/pdbsum/1gyw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1gyw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1gyw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1gyw OCA], [https://pdbe.org/1gyw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1gyw RCSB], [https://www.ebi.ac.uk/pdbsum/1gyw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1gyw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/AP1G1_MOUSE AP1G1_MOUSE]] Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
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[https://www.uniprot.org/uniprot/AP1G1_MOUSE AP1G1_MOUSE] Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Evans, P R]]
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[[Category: Mus musculus]]
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[[Category: Kent, H M]]
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[[Category: Evans PR]]
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[[Category: McMahon, H M]]
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[[Category: Kent HM]]
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[[Category: Miele, A E]]
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[[Category: McMahon HM]]
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[[Category: Owen, D J]]
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[[Category: Miele AE]]
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[[Category: Adaptor]]
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[[Category: Owen DJ]]
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[[Category: Coated pit]]
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[[Category: Endocytosis]]
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Current revision

Gamma-adaptin appendage domain from clathrin adaptor AP1 A753D mutant

PDB ID 1gyw

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