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1h0r
From Proteopedia
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| - | [[Image:1h0r.png|left|200px]] | ||
| - | + | ==Type II Dehydroquinase from Mycobacterium tuberculosis complexed with 2,3-anhydro-quinic acid== | |
| + | <StructureSection load='1h0r' size='340' side='right'caption='[[1h0r]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[1h0r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. The April 2010 RCSB PDB [https://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/index.html Molecule of the Month] feature on ''Concanavalin A and Circular Permutation'' by David Goodsell is [https://dx.doi.org/10.2210/rcsb_pdb/mom_2010_4 10.2210/rcsb_pdb/mom_2010_4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H0R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1H0R FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FA1:2,3+-ANHYDRO-QUINIC+ACID'>FA1</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1h0r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h0r OCA], [https://pdbe.org/1h0r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1h0r RCSB], [https://www.ebi.ac.uk/pdbsum/1h0r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1h0r ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/AROQ_MYCTU AROQ_MYCTU] Catalyzes a trans-dehydration via an enolate intermediate (By similarity).[HAMAP-Rule:MF_00169] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/h0/1h0r_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1h0r ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | == | + | ==See Also== |
| - | + | *[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]] | |
| - | + | __TOC__ | |
| - | + | </StructureSection> | |
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| - | [[ | + | |
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[[Category: Concanavalin A and Circular Permutation]] | [[Category: Concanavalin A and Circular Permutation]] | ||
| - | [[Category: Mycobacterium tuberculosis]] | + | [[Category: Large Structures]] |
| + | [[Category: Mycobacterium tuberculosis H37Rv]] | ||
[[Category: RCSB PDB Molecule of the Month]] | [[Category: RCSB PDB Molecule of the Month]] | ||
| - | [[Category: Abell | + | [[Category: Abell C]] |
| - | [[Category: Coggins | + | [[Category: Coggins JR]] |
| - | [[Category: Frederickson | + | [[Category: Frederickson M]] |
| - | [[Category: Lapthorn | + | [[Category: Lapthorn AJ]] |
| - | [[Category: Robinson | + | [[Category: Robinson DA]] |
| - | [[Category: Roszak | + | [[Category: Roszak AW]] |
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Current revision
Type II Dehydroquinase from Mycobacterium tuberculosis complexed with 2,3-anhydro-quinic acid
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