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1od8

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==Xylanase Xyn10A from Streptomyces lividans in complex with xylobio-isofagomine lactam==
==Xylanase Xyn10A from Streptomyces lividans in complex with xylobio-isofagomine lactam==
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<StructureSection load='1od8' size='340' side='right' caption='[[1od8]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
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<StructureSection load='1od8' size='340' side='right'caption='[[1od8]], [[Resolution|resolution]] 1.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1od8]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"actinomyces_lividans"_krasil'nikov_et_al._1965 "actinomyces lividans" krasil'nikov et al. 1965]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OD8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1OD8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1od8]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_lividans Streptomyces lividans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OD8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OD8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XDL:XYLOSE-DERIVED+ISOFAGOMINE+LACTAM'>XDL</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.05&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1e0v|1e0v]], [[1e0w|1e0w]], [[1e0x|1e0x]], [[1knl|1knl]], [[1knm|1knm]], [[1mc9|1mc9]], [[1xas|1xas]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IMD:IMIDAZOLE'>IMD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=XDL:XYLOSE-DERIVED+ISOFAGOMINE+LACTAM'>XDL</scene>, <scene name='pdbligand=XYP:BETA-D-XYLOPYRANOSE'>XYP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Endo-1,4-beta-xylanase Endo-1,4-beta-xylanase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.8 3.2.1.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1od8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1od8 OCA], [https://pdbe.org/1od8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1od8 RCSB], [https://www.ebi.ac.uk/pdbsum/1od8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1od8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1od8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1od8 OCA], [http://pdbe.org/1od8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1od8 RCSB], [http://www.ebi.ac.uk/pdbsum/1od8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1od8 ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/XYNA_STRLI XYNA_STRLI]] Contributes to hydrolyze hemicellulose, the major component of plant cell-walls. XLNA and XLNB seem to act sequentially on the substrate to yield xylobiose and xylose as carbon sources.
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[https://www.uniprot.org/uniprot/XYNA_STRLI XYNA_STRLI] Contributes to hydrolyze hemicellulose, the major component of plant cell-walls. XLNA and XLNB seem to act sequentially on the substrate to yield xylobiose and xylose as carbon sources.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/od/1od8_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/od/1od8_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Actinomyces lividans krasil'nikov et al. 1965]]
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[[Category: Large Structures]]
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[[Category: Endo-1,4-beta-xylanase]]
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[[Category: Streptomyces lividans]]
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[[Category: Davies, G J]]
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[[Category: Davies GJ]]
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[[Category: Gloster, T M]]
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[[Category: Gloster TM]]
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[[Category: Roberts, S]]
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[[Category: Roberts S]]
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[[Category: Glycoside hydrolase family 10]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase-lectin complex]]
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[[Category: Hydrolase/lectin]]
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[[Category: Isofagomine lactam]]
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[[Category: Lectin]]
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[[Category: Transition state mimic]]
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[[Category: Xylan degradation]]
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[[Category: Xylanase]]
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Current revision

Xylanase Xyn10A from Streptomyces lividans in complex with xylobio-isofagomine lactam

PDB ID 1od8

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