This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1qls

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:48, 13 December 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
 +
==S100C (S100A11),OR CALGIZZARIN, IN COMPLEX WITH ANNEXIN I N-TERMINUS==
==S100C (S100A11),OR CALGIZZARIN, IN COMPLEX WITH ANNEXIN I N-TERMINUS==
-
<StructureSection load='1qls' size='340' side='right' caption='[[1qls]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
+
<StructureSection load='1qls' size='340' side='right'caption='[[1qls]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1qls]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pig Pig]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QLS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1QLS FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1qls]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1QLS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1QLS FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1a4p|1a4p]], [[1bt6|1bt6]], [[1bo9|1bo9]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1qls FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qls OCA], [https://pdbe.org/1qls PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1qls RCSB], [https://www.ebi.ac.uk/pdbsum/1qls PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1qls ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1qls FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1qls OCA], [http://pdbe.org/1qls PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1qls RCSB], [http://www.ebi.ac.uk/pdbsum/1qls PDBsum]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/S10AB_PIG S10AB_PIG]] Facilitates the differentiation and the cornification of keratinocytes (By similarity). [[http://www.uniprot.org/uniprot/ANXA1_HUMAN ANXA1_HUMAN]] Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis. This protein regulates phospholipase A2 activity. It seems to bind from two to four calcium ions with high affinity.
+
[https://www.uniprot.org/uniprot/S10AB_PIG S10AB_PIG] Facilitates the differentiation and the cornification of keratinocytes (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ql/1qls_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ql/1qls_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1qls ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 31: Line 31:
==See Also==
==See Also==
-
*[[Annexin|Annexin]]
+
*[[Annexin 3D structures|Annexin 3D structures]]
-
*[[S100 protein|S100 protein]]
+
*[[S100 proteins 3D structures|S100 proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Pig]]
+
[[Category: Homo sapiens]]
-
[[Category: Gerke, V]]
+
[[Category: Large Structures]]
-
[[Category: Lewit-Bentley, A]]
+
[[Category: Sus scrofa]]
-
[[Category: Osterloh, D]]
+
[[Category: Gerke V]]
-
[[Category: Renouard, M]]
+
[[Category: Lewit-Bentley A]]
-
[[Category: Rety, S]]
+
[[Category: Osterloh D]]
-
[[Category: Russo-Marie, F]]
+
[[Category: Renouard M]]
-
[[Category: Sopkova, J]]
+
[[Category: Rety S]]
-
[[Category: Calcium/phospholipid binding protein]]
+
[[Category: Russo-Marie F]]
-
[[Category: Ef-hand protein]]
+
[[Category: Sopkova J]]
-
[[Category: Ligand of annexin ii]]
+
-
[[Category: Metal-binding protein-inhibitor complex]]
+
-
[[Category: Metal-binding protein/inhibitor]]
+
-
[[Category: S100 family]]
+

Current revision

S100C (S100A11),OR CALGIZZARIN, IN COMPLEX WITH ANNEXIN I N-TERMINUS

PDB ID 1qls

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools