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1uvk

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==The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex==
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<StructureSection load='1uvk' size='340' side='right' caption='[[1uvk]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
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==The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex==
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<StructureSection load='1uvk' size='340' side='right'caption='[[1uvk]], [[Resolution|resolution]] 2.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1uvk]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Bpph6 Bpph6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UVK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1UVK FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1uvk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_virus_phi6 Pseudomonas virus phi6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1UVK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1UVK FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.45&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GTP:GUANOSINE-5-TRIPHOSPHATE'>GTP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=POP:PYROPHOSPHATE+2-'>POP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1uvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uvk OCA], [https://pdbe.org/1uvk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1uvk RCSB], [https://www.ebi.ac.uk/pdbsum/1uvk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1uvk ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uvk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uvk OCA], [http://pdbe.org/1uvk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1uvk RCSB], [http://www.ebi.ac.uk/pdbsum/1uvk PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RDRP_BPPH6 RDRP_BPPH6]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bpph6]]
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[[Category: Large Structures]]
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Pseudomonas virus phi6]]
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[[Category: Bamford, D]]
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[[Category: Bamford D]]
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[[Category: Butcher, S]]
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[[Category: Butcher S]]
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[[Category: Grimes, J M]]
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[[Category: Grimes JM]]
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[[Category: Makeyev, E V]]
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[[Category: Makeyev EV]]
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[[Category: Salgado, P S]]
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[[Category: Salgado PS]]
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[[Category: Stuart, D I]]
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[[Category: Stuart DI]]
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[[Category: Oligonucleotide]]
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[[Category: Polymerase]]
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[[Category: Polymerase-complex]]
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[[Category: Transferase]]
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The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex

PDB ID 1uvk

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