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1w39

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(New page: 200px<br /><applet load="1w39" size="450" color="white" frame="true" align="right" spinBox="true" caption="1w39, resolution 3.75&Aring;" /> '''CRYSTAL STRUCTURE OF...)
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[[Image:1w39.gif|left|200px]]<br /><applet load="1w39" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1w39, resolution 3.75&Aring;" />
 
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'''CRYSTAL STRUCTURE OF AN ARTIFICIAL TOP COMPONENT OF TURNIP YELLOW MOSAIC VIRUS'''<br />
 
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==Overview==
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==Crystal structure of an artificial top component of turnip yellow mosaic virus==
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Empty capsids (artificial top component) of turnip yellow mosaic virus, were co-crystallized with an encapsidation initiator RNA hairpin. No clear, density was observed for the RNA, but there were clear differences in the, conformation of a loop of the coat protein at the opening of the, pentameric capsomer (formed by five A-subunits) protruding from the, capsid, compared to the corresponding loop in the intact virus. Further, differences were found at the N terminus of the A-subunit. These, differences have implications for the mechanism of decapsidation of the, virus, required for infection.
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<StructureSection load='1w39' size='340' side='right'caption='[[1w39]], [[Resolution|resolution]] 3.75&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1w39]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W39 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W39 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.75&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w39 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w39 OCA], [https://pdbe.org/1w39 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w39 RCSB], [https://www.ebi.ac.uk/pdbsum/1w39 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w39 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/COAT_TYMV COAT_TYMV]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w3/1w39_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w39 ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Empty capsids (artificial top component) of turnip yellow mosaic virus were co-crystallized with an encapsidation initiator RNA hairpin. No clear density was observed for the RNA, but there were clear differences in the conformation of a loop of the coat protein at the opening of the pentameric capsomer (formed by five A-subunits) protruding from the capsid, compared to the corresponding loop in the intact virus. Further differences were found at the N terminus of the A-subunit. These differences have implications for the mechanism of decapsidation of the virus, required for infection.
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==About this Structure==
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Crystal structure of an empty capsid of turnip yellow mosaic virus.,van Roon AM, Bink HH, Plaisier JR, Pleij CW, Abrahams JP, Pannu NS J Mol Biol. 2004 Aug 27;341(5):1205-14. PMID:15321716<ref>PMID:15321716</ref>
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1W39 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Turnip_yellow_mosaic_virus Turnip yellow mosaic virus]. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W39 OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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Crystal structure of an empty capsid of turnip yellow mosaic virus., van Roon AM, Bink HH, Plaisier JR, Pleij CW, Abrahams JP, Pannu NS, J Mol Biol. 2004 Aug 27;341(5):1205-14. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15321716 15321716]
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</div>
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[[Category: Single protein]]
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<div class="pdbe-citations 1w39" style="background-color:#fffaf0;"></div>
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[[Category: Turnip yellow mosaic virus]]
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[[Category: Abrahams, J.P.]]
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[[Category: Bink, H.H.J.]]
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[[Category: Pannu, N.S.]]
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[[Category: Plaisier, J.R.]]
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[[Category: Pleij, C.W.A.]]
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[[Category: Roon, A.M.M.Van.]]
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[[Category: artificial top component]]
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[[Category: capsid protein]]
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[[Category: crystallography]]
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[[Category: icosahedral virus]]
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[[Category: tymv]]
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[[Category: virus]]
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[[Category: virus/viral protein]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 05:12:58 2007''
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==See Also==
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Turnip yellow mosaic virus]]
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[[Category: Abrahams JP]]
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[[Category: Bink HHJ]]
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[[Category: Pannu NS]]
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[[Category: Plaisier JR]]
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[[Category: Pleij CWA]]
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[[Category: Van Roon AMM]]

Current revision

Crystal structure of an artificial top component of turnip yellow mosaic virus

PDB ID 1w39

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