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1w7f

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[[Image:1w7f.gif|left|200px]]<br />
 
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<applet load="1w7f" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1w7f, resolution 1.80&Aring;" />
 
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'''CRYSTAL STRUCTURE OF THE CLASS A BETA-LACTAMASE BS3 INHIBITED WITH ISOCITRATE'''<br />
 
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==About this Structure==
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==Crystal structure of the class A beta-lactamase BS3 inhibited with isocitrate==
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1W7F is a [[http://en.wikipedia.org/wiki/Single_protein Single protein]] structure of sequence from [[http://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]] with ICT as [[http://en.wikipedia.org/wiki/ligand ligand]]. Active as [[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase]], with EC number [[http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6]]. Structure known Active Site: AC1. Full crystallographic information is available from [[http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W7F OCA]].
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<StructureSection load='1w7f' size='340' side='right'caption='[[1w7f]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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[[Category: Bacillus licheniformis]]
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== Structural highlights ==
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[[Category: Beta-lactamase]]
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<table><tr><td colspan='2'>[[1w7f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_licheniformis Bacillus licheniformis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W7F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W7F FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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[[Category: Charlier, P.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ICT:ISOCITRIC+ACID'>ICT</scene></td></tr>
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[[Category: Herman, R.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w7f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w7f OCA], [https://pdbe.org/1w7f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w7f RCSB], [https://www.ebi.ac.uk/pdbsum/1w7f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w7f ProSAT]</span></td></tr>
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[[Category: Petrella, S.]]
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</table>
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[[Category: Sauvage, E.]]
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== Function ==
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[[Category: ICT]]
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[https://www.uniprot.org/uniprot/BLAC_BACLI BLAC_BACLI]
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[[Category: bacillus licheniformis hydrolase]]
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== Evolutionary Conservation ==
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[[Category: beta-lactamase]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: isocitrate]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w7/1w7f_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w7f ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Oct 30 16:27:24 2007''
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
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__TOC__
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</StructureSection>
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[[Category: Bacillus licheniformis]]
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[[Category: Large Structures]]
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[[Category: Charlier P]]
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[[Category: Herman R]]
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[[Category: Petrella S]]
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[[Category: Sauvage E]]

Current revision

Crystal structure of the class A beta-lactamase BS3 inhibited with isocitrate

PDB ID 1w7f

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