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1w9k

From Proteopedia

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[[Image:1w9k.gif|left|200px]]<br />
 
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<applet load="1w9k" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1w9k, resolution 2.05&Aring;" />
 
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'''DICTYOSTELIUM DISCOIDEUM MYOSIN II MOTOR DOMAIN S456E WITH BOUND MGADP-BEFX'''<br />
 
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==About this Structure==
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==Dictyostelium discoideum Myosin II motor domain S456E with bound MgADP-BeFx==
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1W9K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum] with MG, ADP, BEF and EDO as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Myosin_ATPase Myosin ATPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.1 3.6.4.1] Structure known Active Site: AC1. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1W9K OCA].
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<StructureSection load='1w9k' size='340' side='right'caption='[[1w9k]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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[[Category: Dictyostelium discoideum]]
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== Structural highlights ==
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[[Category: Myosin ATPase]]
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<table><tr><td colspan='2'>[[1w9k]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1W9K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1W9K FirstGlance]. <br>
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[[Category: Single protein]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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[[Category: Coureux, P.D.]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=BEF:BERYLLIUM+TRIFLUORIDE+ION'>BEF</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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[[Category: Houdusse, A.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1w9k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1w9k OCA], [https://pdbe.org/1w9k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1w9k RCSB], [https://www.ebi.ac.uk/pdbsum/1w9k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1w9k ProSAT]</span></td></tr>
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[[Category: Morris, C.A.]]
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</table>
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[[Category: Sweeney, H.L.]]
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== Function ==
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[[Category: Wells, A.L.]]
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[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
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[[Category: ADP]]
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== Evolutionary Conservation ==
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[[Category: BEF]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: EDO]]
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Check<jmol>
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[[Category: MG]]
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<jmolCheckbox>
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[[Category: molecular motor]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w9/1w9k_consurf.spt"</scriptWhenChecked>
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[[Category: muscle contraction]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: mutant]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: myosin]]
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</jmolCheckbox>
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[[Category: powerstroke]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1w9k ConSurf].
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<div style="clear:both"></div>
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Mon Nov 5 17:29:49 2007''
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==See Also==
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*[[Myosin 3D Structures|Myosin 3D Structures]]
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__TOC__
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</StructureSection>
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[[Category: Dictyostelium discoideum]]
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[[Category: Large Structures]]
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[[Category: Coureux P-D]]
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[[Category: Houdusse A]]
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[[Category: Morris CA]]
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[[Category: Sweeney HL]]
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[[Category: Wells AL]]

Current revision

Dictyostelium discoideum Myosin II motor domain S456E with bound MgADP-BeFx

PDB ID 1w9k

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