This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2bs1

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:54, 13 December 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
 +
==MS2 (N87AE89K mutant) - Qbeta RNA hairpin complex==
==MS2 (N87AE89K mutant) - Qbeta RNA hairpin complex==
-
<StructureSection load='2bs1' size='340' side='right' caption='[[2bs1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
+
<StructureSection load='2bs1' size='340' side='right'caption='[[2bs1]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2bs1]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Enterobacterio_phage_ms2 Enterobacterio phage ms2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS1 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2BS1 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2bs1]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_phage_MS2 Escherichia phage MS2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2BS1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2BS1 FirstGlance]. <br>
-
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1aq3|1aq3]], [[1aq4|1aq4]], [[1bms|1bms]], [[1dzs|1dzs]], [[1gkv|1gkv]], [[1gkw|1gkw]], [[1kuo|1kuo]], [[1msc|1msc]], [[1mst|1mst]], [[1mva|1mva]], [[1mvb|1mvb]], [[1u1y|1u1y]], [[1zdh|1zdh]], [[1zdi|1zdi]], [[1zdj|1zdj]], [[1zdk|1zdk]], [[2bny|2bny]], [[2bq5|2bq5]], [[2bs0|2bs0]], [[2bu1|2bu1]], [[2c4q|2c4q]], [[2c4y|2c4y]], [[2c4z|2c4z]], [[2c50|2c50]], [[2c51|2c51]], [[2ms2|2ms2]], [[5msf|5msf]], [[6msf|6msf]], [[7msf|7msf]]</td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
-
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2bs1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs1 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2bs1 RCSB], [http://www.ebi.ac.uk/pdbsum/2bs1 PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2bs1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2bs1 OCA], [https://pdbe.org/2bs1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2bs1 RCSB], [https://www.ebi.ac.uk/pdbsum/2bs1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2bs1 ProSAT]</span></td></tr>
-
<table>
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CAPSD_BPMS2 CAPSD_BPMS2] Self-assembles to form the T=3 icosahedral virus shell that protects the viral nucleic acid. Acts as a translational repressor by binding with high specificity to a single stem-loop structure in the genomic RNA that contains the initiation codon of the gene for the viral replicase. Involved in virus assembly through the interaction between a capsid protein dimer and the multiple packaging signals present in the RNA genome.<ref>PMID:16531233</ref> <ref>PMID:18662904</ref> <ref>PMID:26608810</ref> <ref>PMID:8254664</ref> <ref>PMID:9245600</ref> <ref>PMID:9469847</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
-
<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bs/2bs1_consurf.spt"</scriptWhenChecked>
+
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bs/2bs1_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
-
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
+
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2bs1 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
Line 24: Line 27:
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
 +
<div class="pdbe-citations 2bs1" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Enterobacterio phage ms2]]
+
[[Category: Escherichia phage MS2]]
-
[[Category: Adams, C J.]]
+
[[Category: Large Structures]]
-
[[Category: Baron, A J.]]
+
[[Category: Adams CJ]]
-
[[Category: Grahn, E.]]
+
[[Category: Baron AJ]]
-
[[Category: Helgstrand, C.]]
+
[[Category: Grahn E]]
-
[[Category: Horn, W T.]]
+
[[Category: Helgstrand C]]
-
[[Category: Lago, H.]]
+
[[Category: Horn WT]]
-
[[Category: Liljas, L.]]
+
[[Category: Lago H]]
-
[[Category: Peabody, D S.]]
+
[[Category: Liljas L]]
-
[[Category: Phillips, S E.V.]]
+
[[Category: Peabody DS]]
-
[[Category: Stockley, P G.]]
+
[[Category: Phillips SEV]]
-
[[Category: Stonehouse, N J.]]
+
[[Category: Stockley PG]]
-
[[Category: Tars, K.]]
+
[[Category: Stonehouse NJ]]
-
[[Category: Capsid]]
+
[[Category: Tars K]]
-
[[Category: Hairpin]]
+
-
[[Category: Icosahedral virus]]
+
-
[[Category: Levivirus]]
+
-
[[Category: Virus-rna complex]]
+
-
[[Category: Virus/rna]]
+
-
[[Category: Virus/viral protein/rna]]
+

Current revision

MS2 (N87AE89K mutant) - Qbeta RNA hairpin complex

PDB ID 2bs1

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2bs1"
Personal tools