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2c1y

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==STRUCTURE OF PDI-RELATED CHAPERONE, WIND MUTANT-Y55K==
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<StructureSection load='2c1y' size='340' side='right' caption='[[2c1y]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
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==Structure of PDI-related Chaperone, Wind mutant-Y55K==
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<StructureSection load='2c1y' size='340' side='right'caption='[[2c1y]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2c1y]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C1Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C1Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2c1y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C1Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C1Y FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ovn|1ovn]], [[2c0e|2c0e]], [[2c0f|2c0f]], [[2c0g|2c0g]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c1y OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2c1y RCSB], [http://www.ebi.ac.uk/pdbsum/2c1y PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c1y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c1y OCA], [https://pdbe.org/2c1y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c1y RCSB], [https://www.ebi.ac.uk/pdbsum/2c1y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c1y ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/WBL_DROME WBL_DROME] Probable chaperone protein involved in dorsoventral axis patterning in early embryos. Probably acts by folding and targeting pipe (pip) into the Golgi.<ref>PMID:9568717</ref> <ref>PMID:11076773</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c1/2c1y_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c1/2c1y_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c1y ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2c1y" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
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[[Category: Barnewitz, K.]]
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[[Category: Large Structures]]
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[[Category: Ferrari, D M.]]
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[[Category: Barnewitz K]]
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[[Category: Guo, C.]]
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[[Category: Ferrari DM]]
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[[Category: Ma, Q.]]
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[[Category: Guo C]]
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[[Category: Sevvana, M.]]
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[[Category: Ma Q]]
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[[Category: Sheldrick, G M.]]
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[[Category: Sevvana M]]
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[[Category: Soling, H D.]]
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[[Category: Sheldrick GM]]
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[[Category: Chaperone]]
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[[Category: Soling H-D]]
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[[Category: Developmental protein]]
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[[Category: Dorsal-ventral patterning]]
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[[Category: Endoplasmic reticulum]]
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[[Category: Pdi]]
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[[Category: Pdi-dbeta]]
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[[Category: Pipe]]
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[[Category: Protein disulfide isomerase]]
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[[Category: Wind]]
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[[Category: Wind mutant]]
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[[Category: Windbeutel]]
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Current revision

Structure of PDI-related Chaperone, Wind mutant-Y55K

PDB ID 2c1y

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