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2c6x
From Proteopedia
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| - | [[Image:2c6x.gif|left|200px]]<br /> | ||
| - | <applet load="2c6x" size="450" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2c6x, resolution 3.40Å" /> | ||
| - | '''STRUCTURE OF BACILLUS SUBTILIS CITRATE SYNTHASE'''<br /> | ||
| - | == | + | ==Structure of Bacillus subtilis citrate synthase== |
| - | + | <StructureSection load='2c6x' size='340' side='right'caption='[[2c6x]], [[Resolution|resolution]] 3.40Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | [ | + | <table><tr><td colspan='2'>[[2c6x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C6X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C6X FirstGlance]. <br> |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.4Å</td></tr> | |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=COZ:COENZYME+A'>COZ</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c6x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c6x OCA], [https://pdbe.org/2c6x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c6x RCSB], [https://www.ebi.ac.uk/pdbsum/2c6x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c6x ProSAT]</span></td></tr> | |
| - | [ | + | </table> |
| - | [[ | + | == Function == |
| - | + | [https://www.uniprot.org/uniprot/CISY_BACSU CISY_BACSU] Might regulate the synthesis and function of enzymes involved in later enzymatic steps of Krebs cycle. Loss in activity results in sporulation defect. | |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | + | Check<jmol> | |
| - | [ | + | <jmolCheckbox> |
| - | [[ | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c6/2c6x_consurf.spt"</scriptWhenChecked> |
| - | [ | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> |
| - | + | <text>to colour the structure by Evolutionary Conservation</text> | |
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c6x ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| - | + | ==See Also== | |
| + | *[[Citrate Synthase 3D structures|Citrate Synthase 3D structures]] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Bacillus subtilis]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Crennell SJ]] | ||
| + | [[Category: Danson MJ]] | ||
| + | [[Category: Hough DW]] | ||
| + | [[Category: Vogl C]] | ||
Current revision
Structure of Bacillus subtilis citrate synthase
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