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2c7g

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==FPRA FROM MYCOBACTERIUM TUBERCULOSIS: HIS57GLN MUTANT==
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<StructureSection load='2c7g' size='340' side='right' caption='[[2c7g]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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==FprA from Mycobacterium tuberculosis: His57Gln mutant==
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<StructureSection load='2c7g' size='340' side='right'caption='[[2c7g]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2c7g]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2C7G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2c7g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C7G FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ODP:4-OXO-NICOTINAMIDE-ADENINE+DINUCLEOTIDE+PHOSPHATE'>ODP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1lqt|1lqt]], [[1lqu|1lqu]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ODP:4-OXO-NICOTINAMIDE-ADENINE+DINUCLEOTIDE+PHOSPHATE'>ODP</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ferredoxin--NADP(+)_reductase Ferredoxin--NADP(+) reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.18.1.2 1.18.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7g OCA], [https://pdbe.org/2c7g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c7g RCSB], [https://www.ebi.ac.uk/pdbsum/2c7g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c7g ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c7g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7g OCA], [http://pdbe.org/2c7g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2c7g RCSB], [http://www.ebi.ac.uk/pdbsum/2c7g PDBsum]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/FPRA_MYCTU FPRA_MYCTU]] May serve as electron transfer protein and supply electrons to P450 systems.
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[https://www.uniprot.org/uniprot/FPRA_MYCTU FPRA_MYCTU] May serve as electron transfer protein and supply electrons to P450 systems.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/2c7g_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/2c7g_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c7g ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aliverti, A]]
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[[Category: Large Structures]]
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[[Category: Coda, A]]
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[[Category: Mycobacterium tuberculosis]]
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[[Category: Mattevi, A]]
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[[Category: Aliverti A]]
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[[Category: Pandini, V]]
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[[Category: Coda A]]
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[[Category: Pennati, A]]
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[[Category: De Rosa M]]
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[[Category: Razeto, A]]
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[[Category: Mattevi A]]
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[[Category: Rosa, M De]]
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[[Category: Pandini V]]
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[[Category: Vanoni, M A]]
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[[Category: Pennati A]]
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[[Category: Zanetti, G]]
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[[Category: Razeto A]]
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[[Category: Fad]]
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[[Category: Vanoni MA]]
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[[Category: Flavoprotein]]
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[[Category: Zanetti G]]
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[[Category: Nadp]]
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[[Category: Nap+ derivative]]
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[[Category: Oxidoreductase]]
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[[Category: Tuberculosis]]
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Current revision

FprA from Mycobacterium tuberculosis: His57Gln mutant

PDB ID 2c7g

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