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2c9h
From Proteopedia
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| - | [[Image:2c9h.gif|left|200px]]<br /><applet load="2c9h" size="350" color="white" frame="true" align="right" spinBox="true" | ||
| - | caption="2c9h, resolution 1.80Å" /> | ||
| - | '''STRUCTURE OF MITOCHONDRIAL BETA-KETOACYL SYNTHASE'''<br /> | ||
| - | == | + | ==Structure of mitochondrial beta-ketoacyl synthase== |
| - | + | <StructureSection load='2c9h' size='340' side='right'caption='[[2c9h]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2c9h]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C9H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C9H FirstGlance]. <br> | |
| - | [ | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c9h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c9h OCA], [https://pdbe.org/2c9h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c9h RCSB], [https://www.ebi.ac.uk/pdbsum/2c9h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c9h ProSAT]</span></td></tr> | |
| - | [ | + | </table> |
| - | + | == Function == | |
| - | [ | + | [https://www.uniprot.org/uniprot/OXSM_HUMAN OXSM_HUMAN] May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function.<ref>PMID:15668256</ref> |
| - | [ | + | == Evolutionary Conservation == |
| - | [ | + | [[Image:Consurf_key_small.gif|200px|right]] |
| - | [[ | + | Check<jmol> |
| - | + | <jmolCheckbox> | |
| - | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c9/2c9h_consurf.spt"</scriptWhenChecked> | |
| - | + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |
| - | [ | + | <text>to colour the structure by Evolutionary Conservation</text> |
| - | [[ | + | </jmolCheckbox> |
| - | [ | + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c9h ConSurf]. |
| - | + | <div style="clear:both"></div> | |
| - | + | ==See Also== | |
| + | *[[Acyl carrier protein synthase 3D structures|Acyl carrier protein synthase 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Arrowsmith C]] | ||
| + | [[Category: Bunkoczi G]] | ||
| + | [[Category: Edwards A]] | ||
| + | [[Category: Gileadi O]] | ||
| + | [[Category: Oppermann U]] | ||
| + | [[Category: Smee C]] | ||
| + | [[Category: Sundstrom M]] | ||
| + | [[Category: Weigelt J]] | ||
| + | [[Category: Wu X]] | ||
| + | [[Category: Von Delft F]] | ||
Current revision
Structure of mitochondrial beta-ketoacyl synthase
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Bunkoczi G | Edwards A | Gileadi O | Oppermann U | Smee C | Sundstrom M | Weigelt J | Wu X | Von Delft F
