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2c9m

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Current revision (14:10, 13 December 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2c9m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C9M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C9M FirstGlance]. <br>
<table><tr><td colspan='2'>[[2c9m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Oryctolagus_cuniculus Oryctolagus cuniculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C9M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C9M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1fqu|1fqu]], [[1iwo|1iwo]], [[1kju|1kju]], [[1su4|1su4]], [[1t5s|1t5s]], [[1t5t|1t5t]], [[1vfp|1vfp]], [[1wpe|1wpe]], [[1wpg|1wpg]], [[1xp5|1xp5]], [[2agv|2agv]], [[2by4|2by4]], [[2c88|2c88]], [[2c8k|2c8k]], [[2c8l|2c8l]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Calcium-transporting_ATPase Calcium-transporting ATPase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.8 3.6.3.8] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c9m OCA], [https://pdbe.org/2c9m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c9m RCSB], [https://www.ebi.ac.uk/pdbsum/2c9m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c9m ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c9m OCA], [https://pdbe.org/2c9m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c9m RCSB], [https://www.ebi.ac.uk/pdbsum/2c9m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c9m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT]] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
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[https://www.uniprot.org/uniprot/AT2A1_RABIT AT2A1_RABIT] This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Calcium-transporting ATPase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Oryctolagus cuniculus]]
[[Category: Oryctolagus cuniculus]]
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[[Category: Jensen, A M.Lund]]
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[[Category: Lund Jensen A-M]]
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[[Category: Moller, J V]]
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[[Category: Moller JV]]
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[[Category: Nissen, P]]
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[[Category: Nissen P]]
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[[Category: Olesen, C]]
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[[Category: Olesen C]]
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[[Category: Sorensen, T L.M]]
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[[Category: Sorensen TL-M]]
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[[Category: Atp-binding]]
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[[Category: Ca2+-atpase]]
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[[Category: Calcium transport]]
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[[Category: Cation pump]]
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[[Category: Hydrolase]]
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[[Category: Ion transport]]
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[[Category: Membrane protein]]
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[[Category: Metal-binding]]
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[[Category: Modulatory atp]]
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[[Category: Nucleotide-binding]]
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[[Category: P-type atpase]]
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[[Category: Phosphorylation]]
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Current revision

Structure of (SR) Calcium-ATPase in the Ca2E1 state solved in a P1 crystal form.

PDB ID 2c9m

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