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2ce4

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==MANGANESE SUPEROXIDE DISMUTASE (MN-SOD) FROM DEINOCOCCUS RADIODURANS==
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<StructureSection load='2ce4' size='340' side='right' caption='[[2ce4]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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==Manganese Superoxide Dismutase (Mn-SOD) from Deinococcus radiodurans==
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<StructureSection load='2ce4' size='340' side='right'caption='[[2ce4]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2ce4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CE4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2CE4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2ce4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Deinococcus_radiodurans_R1 Deinococcus radiodurans R1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2CE4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2CE4 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1y67|1y67]], [[2cdy|2cdy]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Superoxide_dismutase Superoxide dismutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.15.1.1 1.15.1.1] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2ce4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ce4 OCA], [https://pdbe.org/2ce4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2ce4 RCSB], [https://www.ebi.ac.uk/pdbsum/2ce4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2ce4 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ce4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ce4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2ce4 RCSB], [http://www.ebi.ac.uk/pdbsum/2ce4 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/SODM_DEIRA SODM_DEIRA] Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/2ce4_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ce/2ce4_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2ce4 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2ce4" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Superoxide Dismutase|Superoxide Dismutase]]
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*[[Superoxide dismutase 3D structures|Superoxide dismutase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Deinococcus radiodurans]]
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[[Category: Deinococcus radiodurans R1]]
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[[Category: Superoxide dismutase]]
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[[Category: Large Structures]]
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[[Category: Dennis, R.]]
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[[Category: Dennis R]]
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[[Category: Gordon, E.]]
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[[Category: Gordon E]]
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[[Category: Leonard, G.]]
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[[Category: Leonard G]]
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[[Category: Mccarthy, J.]]
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[[Category: McCarthy J]]
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[[Category: Mcsweeney, S.]]
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[[Category: McSweeney S]]
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[[Category: Micossi, E.]]
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[[Category: Micossi E]]
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[[Category: Moe, E.]]
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[[Category: Moe E]]
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[[Category: Deinococcus radioduran]]
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[[Category: Manganese superoxide dismutase]]
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[[Category: Oxidoreductase]]
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[[Category: Radiation resistance]]
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Current revision

Manganese Superoxide Dismutase (Mn-SOD) from Deinococcus radiodurans

PDB ID 2ce4

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