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2j4u
From Proteopedia
(Difference between revisions)
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| - | [[Image:2j4u.png|left|200px]] | ||
| - | + | ==E.coli OmpC - camel Lactoferrin complex== | |
| - | + | <StructureSection load='2j4u' size='340' side='right'caption='[[2j4u]], [[Resolution|resolution]] 2.99Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2j4u]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Camelus_dromedarius Camelus dromedarius] and [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J4U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2J4U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.99Å</td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2j4u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j4u OCA], [https://pdbe.org/2j4u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2j4u RCSB], [https://www.ebi.ac.uk/pdbsum/2j4u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2j4u ProSAT]</span></td></tr> | |
| - | + | </table> | |
| - | + | == Function == | |
| - | === | + | [https://www.uniprot.org/uniprot/TRFL_CAMDR TRFL_CAMDR] Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate (By similarity). The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity (By similarity). |
| - | + | == Evolutionary Conservation == | |
| - | + | [[Image:Consurf_key_small.gif|200px|right]] | |
| - | == | + | Check<jmol> |
| - | [[2j4u]] is a 8 chain structure | + | <jmolCheckbox> |
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j4/2j4u_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2j4u ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Lactoferrin|Lactoferrin]] | *[[Lactoferrin|Lactoferrin]] | ||
| - | *[[Porin|Porin]] | + | *[[Porin 3D structures|Porin 3D structures]] |
| + | __TOC__ | ||
| + | </StructureSection> | ||
[[Category: Camelus dromedarius]] | [[Category: Camelus dromedarius]] | ||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Acharya RK]] |
| - | [[Category: | + | [[Category: Baalaji S]] |
| - | [[Category: | + | [[Category: Krishnaswamy S]] |
| - | [[Category: | + | [[Category: Singh TP]] |
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Current revision
E.coli OmpC - camel Lactoferrin complex
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